关键词: Aging Animal model Brain disorder CNS Dementia Demyelination Drug trial Human studies Liver damage Melatonin Neuronal death ROS Secretase Sialylation Side effects
Mesh : Alzheimer Disease / drug therapy physiopathology Amyloid Precursor Protein Secretases / antagonists & inhibitors genetics metabolism Animals Aspartic Acid Endopeptidases / antagonists & inhibitors genetics metabolism Brain / drug effects physiopathology Clinical Trials as Topic Disease Models, Animal Heterocyclic Compounds, 2-Ring / adverse effects pharmacology therapeutic use Humans Liver / drug effects physiopathology Mice, Knockout Models, Biological Nootropic Agents / adverse effects pharmacology therapeutic use Picolinic Acids / adverse effects pharmacology therapeutic use Protease Inhibitors / adverse effects pharmacology therapeutic use
来 源:
DOI:10.1016/j.jalz.2013.11.004
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