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Abstract：
From a clinicopathological conference on nine elderly patients with Epstein-Barr virus (EBV)-associated T/natural killer (NK)-cell lymphoma, we have addressed the patients\' backgrounds, clinical manifestations, histopathological findings, cytogenesis, complications and prognoses. Among these elderly patients (>65 years old), seven patients had extranodal NK/T-cell lymphoma, nasal type (ENKL) with an NK-cell phenotype, and two patients had EBV(+) T-cell lymphomas or lymphoproliferative disorders (LPD) with cutaneous lesions mimicking pityriasis lichenoides et varioliformis acuta (PLEVA) or hydroa vacciniforme (HV). No patients had a previous episode of EBV-related symptoms such as infectious mononucleosis, chronic active EBV infection, HV or hypersensitivity to mosquito bites. Elderly patients with ENKL may show the centroblastoid variant. EBV(+) CD8(+) CD56(+/-) lymphocytes may be responsible for the development of PLEVA or HV-like cutaneous lesions in the elderly.
摘要：
来自9例老年患者EB病毒（EBV）相关T/自然杀伤（NK）细胞淋巴瘤的临床病理会议，我们已经解决了病人的背景，临床表现，组织病理学发现,细胞发生，并发症和预后。在这些老年患者（>65岁）中，7例患者患有结外NK/T细胞淋巴瘤，具有NK细胞表型的鼻型（ENKL），两名患者患有EBV（）T细胞淋巴瘤或淋巴增殖性疾病（LPD），并伴有皮肤病变，模仿了地衣糠疹和变形杆菌（PLEVA）或水生疫苗（HV）。没有患者先前有EBV相关症状，如传染性单核细胞增多症，慢性活动性EBV感染，HV或对蚊子叮咬过敏。老年ENKL患者可能表现为中心囊样变异。EBV（）CD8（）CD56（/-）淋巴细胞可能是老年人PLEVA或HV样皮肤病变发展的原因。
