NAD ( P ) H 及其衍生物对哺乳动物昼夜节律转录因子 NPAS2 的 DNA 结合活性的影响。
关键词: Clock genes DNA-binding activity E-box EMS HAT NAAD NAD(P)H cofactor NPAS2 PAS domain Transcription electrophoretic mobility shift histone acetyltransferase neuronal PAS domain protein 2 nicotinic acid adenine dinucleotide
Mesh : ARNTL Transcription Factors / antagonists & inhibitors genetics metabolism Animals Basic Helix-Loop-Helix Transcription Factors / genetics metabolism Circadian Rhythm / genetics physiology DNA-Binding Proteins / genetics metabolism Electrophoretic Mobility Shift Assay Humans Mice NADP / genetics metabolism physiology Nerve Tissue Proteins / genetics metabolism Protein Binding / genetics Protein Multimerization / genetics Sequence Deletion Up-Regulation / genetics
来 源:
DOI:10.1016/j.bbrc.2013.06.086
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