关键词: CTD Carboxyl-terminal domain DNA topoisomerase IIα DNA topoisomerase IIβ EI ES NMD NoLS Nucleolar Localization Site PAF53 PAR1 Pol I Pol I-associated factor 53 Pol II Pol III RB RNA polymerase I RNA polymerase II RNA polymerse III Retinoblastoma TAF1B TATA box-binding protein TATA box-binding protein (TBP)-associated factor 1 TBP TF TFIIB TFIIE TFIIEalpha TFIIF TFIIIA TFIIIC TTF-I Tgm Top2α Top2β WH WT Wildtype eEF1-A elongation factor 1-A exon-including exon-skipped hPAF49 human Pol I-associated factor 53 ncRNAs noncoding RNAs nonsense mediated decay protease activate the thrombin receptor tRNA gene-mediated termination factor transcription factor transcription factor A for Pol III transcription factor C for Pol II transcription factor C for Pol III transcription factor E alpha for Pol II transcription factor E for Pol II transcription factor F for Pol II winged helix

Mesh : Animals Epigenesis, Genetic Humans Neoplasms / enzymology genetics RNA Polymerase I / chemistry metabolism RNA Polymerase III / chemistry metabolism

来  源:   DOI:10.1016/j.gene.2013.04.009   PDF(Sci-hub)

Abstract:
The Eighth International Biennial Conference on RNA polymerases I and III (the \'Odd Pols\') was held June 7-11, 2012 at The Airlie Center in Warrenton Virginia, USA. It was sponsored by the Universite Laval and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, and organized by Rich Maraia and Tom Moss. The meeting honored the memory of Pierre Thuriaux (Jan 1, 1950-March 18, 2012) and David Schneider reminisced on the important accomplishments his mentor Masayasu Nomura (1927-2011). The goal of the conference was to bring together the world\'s experts on RNA polymerase I and RNA polymerase III to highlight and share their latest results and varied experimental approaches. The meeting drew attendees from twelve countries and most contributed through oral and poster presentations. The talks were organized into several sessions subdivided into 10 distinct topics. The keynote speaker, Ian Willis, opened the meeting with his presentation entitled \"New Regulators of Signaling to Odd Pols\" and the closing presentation was given by Patrick Cramer with his presentation \"Conservation of the RNA polymerase I, II and III transcription initiation machineries\". Here we present some of the highlights from the meeting using summaries provided by the participants.
摘要:
第八届国际双年度RNA聚合酶I和III会议(“OddPos”)于2012年6月7日至11日在弗吉尼亚州沃伦顿的Airlie中心举行,美国。它由拉瓦尔大学和尤尼斯·肯尼迪·施莱弗国家儿童健康与人类发展研究所赞助,NIH,由RichMaraia和TomMoss组织.会议纪念了PierreThuriaux(1950年1月1日至2012年3月18日),DavidSchneider回忆了他的导师MasayasuNomura(1927-2011)的重要成就。会议的目的是汇集世界上RNA聚合酶I和RNA聚合酶III的专家,以强调和分享他们的最新结果和各种实验方法。会议吸引了来自十二个国家的与会者,大多数人通过口头和海报介绍做出了贡献。会谈分为几场会议,分为10个不同的主题。主旨发言人,伊恩·威利斯,会议以题为“向奇怪的波尔斯发出信号的新监管机构”的演讲开幕,最后由PatrickCramer以他的演讲“保护RNA聚合酶I,II和III转录起始机器。“在这里,我们使用与会者提供的摘要介绍会议的一些亮点。
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