Mesh : Albendazole / administration & dosage Animals Anthelmintics / administration & dosage Ascaris suum / isolation & purification Biopsy Enzyme-Linked Immunosorbent Assay Histocytochemistry Humans Japan Larva Migrans, Visceral / complications diagnosis Lung / pathology Male Middle Aged Parasitology / methods Pulmonary Eosinophilia / diagnosis parasitology Radiography, Thoracic Tomography, X-Ray Computed Treatment Outcome

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Abstract:
We report the case of a 62-year-old man who developed eosinophilic pneumonia due to visceral larva migrans (VLM) that was possibly caused by Ascaris suum. The patient, a resident of the middle Kyushu area who was found of eating raw porcine liver, complained of dry cough without dyspnea. The chest radiography showed a migration of infiltrative shadow. Transbronchial lung biopsy of the right middle lobe revealed massive infiltration of eosinophils. The multi-dot enzyme-linked immunosorbent assay (ELISA) and microtiter plate ELISA showed positive results for A. suum; therefore, the patient was diagnosed with VLM caused by A. suum. The patient was administered albendazole (600 mg/day) for 28 days; he recovered successfully with no adverse effects except mild liver dysfunction. Several cases of VLM caused by A. suum have been reported in Japan, with a majority of the cases being reported in Kyushu. Careful history taking of the patient\'s area of residence and dietary habit is essential for the diagnosis of this parasitic disease with underestimated prevalence.
摘要:
我们报告了一名62岁男子的病例,该男子因内脏幼虫迁徙(VLM)而发展为嗜酸性粒细胞肺炎,这可能是由A虫引起的。病人,九州中部地区的一名居民被发现吃生猪肝,主诉干咳无呼吸困难。胸部X线检查显示浸润阴影的迁移。右中叶经支气管肺活检显示大量嗜酸性粒细胞浸润。多点酶联免疫吸附试验(ELISA)和微量滴定板ELISA检测结果均为阳性,因此,该患者被诊断为由A.suum引起的VLM。患者服用阿苯达唑(600mg/天)28天;他成功康复,除轻度肝功能障碍外,无不良反应。日本已经报道了几例由A.suum引起的VLM病例,大多数病例是在九州报告的。仔细记录患者的居住地和饮食习惯的病史对于诊断这种患病率被低估的寄生虫病至关重要。
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