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Abstract：
Unrelated donor SCT activity is increasing, and in 5-10% of cases a subsequent donation of stem cells or donor lymphocytes may be requested. Second donations of stem cells are not associated with an increased chance of donor complications, but the yield of CD34+ cells may be lower in some donors. It is acceptable practice for any registry to request subsequent donations and it is recommended that donors should be counselled about this possibility before their first donation. Guidance is provided on the requirements for further medical assessment, the procedures used to agree requests, frequency and timing of donation and timing and duration of donor follow up.
摘要：
无关的供体SCT活动正在增加，在5-10％的病例中，可能会要求随后捐献干细胞或供体淋巴细胞。干细胞的第二次捐赠与供体并发症的机会增加无关，但CD34+细胞的产量在一些供体中可能较低。任何登记册都可以要求随后的捐赠，这是可以接受的做法，建议捐助者在首次捐赠之前应就这种可能性进行咨询。提供了进一步医疗评估要求的指导，用于同意请求的程序，捐赠的频率和时间以及捐赠者随访的时间和持续时间。
