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Abstract：
OBJECTIVE: The aim was to formulate practice guidelines for the diagnosis and treatment of hyperprolactinemia.
METHODS: The Task Force consisted of Endocrine Society-appointed experts, a methodologist, and a medical writer.
METHODS: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence.
METHODS: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of The Endocrine Society, The European Society of Endocrinology, and The Pituitary Society reviewed and commented on preliminary drafts of these guidelines.
CONCLUSIONS: Practice guidelines are presented for diagnosis and treatment of patients with elevated prolactin levels. These include evidence-based approaches to assessing the cause of hyperprolactinemia, treating drug-induced hyperprolactinemia, and managing prolactinomas in nonpregnant and pregnant subjects. Indications and side effects of therapeutic agents for treating prolactinomas are also presented.
METHODS: The Task Force consisted of Endocrine Society-appointed experts, a methodologist, and a medical writer.
METHODS: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence.
METHODS: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of The Endocrine Society, The European Society of Endocrinology, and The Pituitary Society reviewed and commented on preliminary drafts of these guidelines.
CONCLUSIONS: Practice guidelines are presented for diagnosis and treatment of patients with elevated prolactin levels. These include evidence-based approaches to assessing the cause of hyperprolactinemia, treating drug-induced hyperprolactinemia, and managing prolactinomas in nonpregnant and pregnant subjects. Indications and side effects of therapeutic agents for treating prolactinomas are also presented.
摘要：
目的：制定高泌乳素血症诊断和治疗的实践指南。
方法：工作组由内分泌学会指定的专家组成，一个方法学家,一个医学作家。
方法：本基于证据的指南是使用建议分级制定的，评估,发展,和评估(等级)系统来描述建议的强度和证据的质量。
方法：一次小组会议，几个电话会议，电子邮件通信促成了共识。内分泌学会的委员会和成员，欧洲内分泌学会，垂体学会审查并评论了这些指南的初步草案。
结论：针对催乳素水平升高患者的诊断和治疗提出了实践指南。这些包括基于证据的方法来评估高催乳素血症的原因，治疗药物引起的高泌乳素血症，和管理非妊娠和妊娠受试者的泌乳素瘤。还提供了用于治疗催乳素瘤的治疗剂的适应症和副作用。
方法：工作组由内分泌学会指定的专家组成，一个方法学家,一个医学作家。
方法：本基于证据的指南是使用建议分级制定的，评估,发展,和评估(等级)系统来描述建议的强度和证据的质量。
方法：一次小组会议，几个电话会议，电子邮件通信促成了共识。内分泌学会的委员会和成员，欧洲内分泌学会，垂体学会审查并评论了这些指南的初步草案。
结论：针对催乳素水平升高患者的诊断和治疗提出了实践指南。这些包括基于证据的方法来评估高催乳素血症的原因，治疗药物引起的高泌乳素血症，和管理非妊娠和妊娠受试者的泌乳素瘤。还提供了用于治疗催乳素瘤的治疗剂的适应症和副作用。
