{Reference Type}: Journal Article {Title}: Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. {Author}: Melmed S;Casanueva FF;Hoffman AR;Kleinberg DL;Montori VM;Schlechte JA;Wass JA; ; {Journal}: J Clin Endocrinol Metab {Volume}: 96 {Issue}: 2 {Year}: Feb 2011 {Factor}: 6.134 {DOI}: 10.1210/jc.2010-1692 {Abstract}: OBJECTIVE: The aim was to formulate practice guidelines for the diagnosis and treatment of hyperprolactinemia.
METHODS: The Task Force consisted of Endocrine Society-appointed experts, a methodologist, and a medical writer.
METHODS: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence.
METHODS: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of The Endocrine Society, The European Society of Endocrinology, and The Pituitary Society reviewed and commented on preliminary drafts of these guidelines.
CONCLUSIONS: Practice guidelines are presented for diagnosis and treatment of patients with elevated prolactin levels. These include evidence-based approaches to assessing the cause of hyperprolactinemia, treating drug-induced hyperprolactinemia, and managing prolactinomas in nonpregnant and pregnant subjects. Indications and side effects of therapeutic agents for treating prolactinomas are also presented.