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Abstract：
OBJECTIVE: To make recommendations based on a critical review of the evidence for the timing of the introduction of solid foods and its possible role in the development of food allergy.
METHODS: MEDLINE searches using the following search algorithm: [weaning AND infant AND allergy]/[food allergy AND sensitization]/[dietary prevention AND food allergy OR allergens]/[Jan 1980-Feb 2006].
METHODS: Using the authors\' clinical experience and research expertise, 52 studies were retrieved that satisfied the following conditions: English language, journal impact factor above 1 or scientific society, expert, or institutional publication, and appraisable using the World Health Organization categories of evidence.
RESULTS: Available information suggests that early introduction can increase the risk of food allergy, that avoidance of solids can prevent the development of specific food allergies, that some foods are more allergenic than others, and that some food allergies are more persistent than others.
CONCLUSIONS: Pediatricians and allergists should cautiously individualize the introduction of solids into the infants\' diet. With assessed risk of allergy, the optimal age for the introduction of selected supplemental foods should be 6 months, dairy products 12 months, hen\'s egg 24 months, and peanut, tree nuts, fish, and seafood at least 36 months. For all infants, complementary feeding can be introduced from the sixth month, and egg, peanut, tree nuts, fish, and seafood introduction require caution. Foods should be introduced one at a time in small amounts. Mixed foods containing various food allergens should not be given unless tolerance to every ingredient has been assessed.
METHODS: MEDLINE searches using the following search algorithm: [weaning AND infant AND allergy]/[food allergy AND sensitization]/[dietary prevention AND food allergy OR allergens]/[Jan 1980-Feb 2006].
METHODS: Using the authors\' clinical experience and research expertise, 52 studies were retrieved that satisfied the following conditions: English language, journal impact factor above 1 or scientific society, expert, or institutional publication, and appraisable using the World Health Organization categories of evidence.
RESULTS: Available information suggests that early introduction can increase the risk of food allergy, that avoidance of solids can prevent the development of specific food allergies, that some foods are more allergenic than others, and that some food allergies are more persistent than others.
CONCLUSIONS: Pediatricians and allergists should cautiously individualize the introduction of solids into the infants\' diet. With assessed risk of allergy, the optimal age for the introduction of selected supplemental foods should be 6 months, dairy products 12 months, hen\'s egg 24 months, and peanut, tree nuts, fish, and seafood at least 36 months. For all infants, complementary feeding can be introduced from the sixth month, and egg, peanut, tree nuts, fish, and seafood introduction require caution. Foods should be introduced one at a time in small amounts. Mixed foods containing various food allergens should not be given unless tolerance to every ingredient has been assessed.
摘要：
目的：根据对引入固体食物的时间及其在食物过敏发展中的可能作用的证据的严格审查，提出建议。
方法：使用以下搜索算法进行MEDLINE搜索：[断奶和婴儿和过敏]/[食物过敏和致敏]/[饮食预防和食物过敏或过敏原]/[1980年1月-2006年2月]。
方法：利用作者的临床经验和研究专长，检索到52项符合以下条件的研究：英语，期刊影响因子高于1或科学学会，专家,或机构出版物，并且可以使用世界卫生组织类别的证据进行评估。
结果：现有信息表明，早期引入会增加食物过敏的风险，避免固体可以防止特定食物过敏的发展，有些食物比其他食物更容易过敏，有些食物过敏比其他食物过敏更持久。
结论：儿科医生和变态反应学家应谨慎地将固体成分引入婴儿饮食中。评估过敏风险，引入所选补充食品的最佳年龄应为6个月，乳制品12个月，鸡蛋24个月，还有花生,树坚果,鱼,和海鲜至少36个月。对于所有的婴儿，补充喂养可以从第六个月开始，鸡蛋,花生,树坚果,鱼,和海鲜介绍需要谨慎。食物应该一次少量引入一个。除非已经评估了对每种成分的耐受性，否则不应给予含有各种食物过敏原的混合食物。
方法：使用以下搜索算法进行MEDLINE搜索：[断奶和婴儿和过敏]/[食物过敏和致敏]/[饮食预防和食物过敏或过敏原]/[1980年1月-2006年2月]。
方法：利用作者的临床经验和研究专长，检索到52项符合以下条件的研究：英语，期刊影响因子高于1或科学学会，专家,或机构出版物，并且可以使用世界卫生组织类别的证据进行评估。
结果：现有信息表明，早期引入会增加食物过敏的风险，避免固体可以防止特定食物过敏的发展，有些食物比其他食物更容易过敏，有些食物过敏比其他食物过敏更持久。
结论：儿科医生和变态反应学家应谨慎地将固体成分引入婴儿饮食中。评估过敏风险，引入所选补充食品的最佳年龄应为6个月，乳制品12个月，鸡蛋24个月，还有花生,树坚果,鱼,和海鲜至少36个月。对于所有的婴儿，补充喂养可以从第六个月开始，鸡蛋,花生,树坚果,鱼,和海鲜介绍需要谨慎。食物应该一次少量引入一个。除非已经评估了对每种成分的耐受性，否则不应给予含有各种食物过敏原的混合食物。
