Abstract:
Biopsy of the kidney should never be undertaken without careful consideration of the risks vs benefits. Given the importance of a correct diagnosis in the treatment and prognosis of renal disease, the pathological evaluation should use all available modalities. Native kidney biopsies require examination by light microscopy, immunohistochemistry and electron microscopy. The processing of the renal biopsy is complex and requires the support of a fully equipped anatomic pathology laboratory. Technical expertise is required to process the small fragments of tissue and to produce sections of highest quality. The correct diagnosis requires a well-trained renal pathologist with thorough knowledge of not only renal pathology but also renal medicine in order to correlate intricate tissue-derived information with detailed clinical data. In view of the importance and consequences of the pathologic diagnosis, the Renal Pathology Society appointed an Ad Hoc Committee on Practice Guidelines, to define the essential ingredients necessary to provide quality renal pathology diagnoses. This document incorporates the consensus opinions of the committee and the RPS membership at large.
摘要:
在没有仔细考虑风险与收益的情况下,绝不能进行肾脏活检。鉴于正确诊断在肾脏疾病的治疗和预后中的重要性,病理评估应使用所有可用的方式。天然肾脏活检需要通过光学显微镜检查,免疫组织化学和电子显微镜。肾活检的处理很复杂,需要设备齐全的解剖病理学实验室的支持。需要技术专长来处理组织的小碎片并产生最高质量的切片。正确的诊断需要训练有素的肾脏病理学家,不仅对肾脏病理学而且对肾脏医学都有透彻的了解,以便将复杂的组织衍生信息与详细的临床数据相关联。鉴于病理诊断的重要性和后果,肾脏病理学会任命了一个关于实践准则的特设委员会,定义提供高质量肾脏病理诊断所需的基本成分。该文件纳入了委员会和整个RPS成员的共识意见。