lipoma

脂肪瘤病

脂肪瘤病是一种体内弥漫性脂肪过多沉积的疾病。虽然在WHO软组织和骨肿瘤分类中被认为是一个单一的实体 7,脂肪瘤病包括各种在人口统计学、分布和病因上存在异质性的疾病。重要的是,许多在身体某些区域有异常脂肪堆积的疾病(脂肪瘤病)也可能在其他区域同时减少脂肪(脂肪营养不良),HIV相关的脂肪营养不良就是一个很好的例子。


脂肪瘤病状况


   关联条件

病理学

无论病因如何,脂肪瘤病在组织学上的特征是成熟的脂肪细胞排列成小叶和片状

治疗和预后

在许多情况下,不需要治疗,或者可以治疗根本原因(例如库欣综合征)。当明显或有美容问题时,可以进行手术切除,尽管复发很常见.

有时,如果大量脂肪堆积会导致机械压迫,并导致区域症状,这取决于位置(例如神经根/马尾压迫或喉压迫)。

鉴别诊断

可能的影像学鉴别诊断考虑因素包括:

  • 1. Bryk D, Young RS, Morris N. Retroperitoneal lipomatosis-report of two cases with an unusual distribution. Gastrointest Radiol. 1979;4 (3): 309-12. Pubmed citation
  • 2. Craig WD, Fanburg-Smith JC, Henry LR et-al. Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics. 2009;29 (1): 261-90. Radiographics (full text) - doi:10.1148/rg.291085203 - Pubmed citation
  • 3. Murphey MD, Carroll JF, Flemming DJ et-al. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004;24 (5): 1433-66. Radiographics (full text) - doi:10.1148/rg.245045120 - Pubmed citation
  • 4. Yesilkaya Y, Duymus M, Topcuoglu M. Pelvic lipomatosis: US and CT diagnosis. Biomed Imaging Interv J. 2012;8 (2): e12. Free text at pubmed - Pubmed citation
  • 5. Watt A, McMillan N. Clinical Radiology. 1999;54 (11): . doi:10.1016/S0009-9260(99)91185-6
  • 6. Catania G, Petralia GA, Migliore M, Cardì F. Diffuse colonic lipomatosis with giant hypertrophy of the epiploic appendices and diverticulosis of the colon. Report of a case and review of the literature. Diseases of the colon and rectum. 38 (7): 769-75. Pubmed
  • 7. Folpe A, Rosenberg A, Nielsen G, Lipomatosis. In: WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours. Lyon (France): International Agency for Research on Cancer; 2020. (WHO classification of tumours series, 5th ed.; vol. 3). https://publications.iarc.fr


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