surgical mesh

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  • 文章类型: Journal Article
    背景:腹股沟疝是机器人或腹腔镜前列腺癌根治术(RP)后常见的并发症之一。RP后腹股沟疝的经腹腹膜前补片成形术(TAPP)由于术后腹膜前腔严重粘连而难以进行。我们在TAPP中引入了一种高腹膜切口方法(HPIA),用于腹股沟疝患者,由于RP后严重粘连而难以进行腹膜解剖。我们评估了TAPP与HPIA对机器人辅助RP(RARP)术后腹股沟疝患者的安全性和有效性。
    方法:通过回顾性分析评估患者特征和手术结果。
    结果:从2014年1月至2017年12月,连续21例患者在RARP术后接受TAPP治疗腹股沟疝。根据Nyhus分类,24个病变为3b型,3个为3a型。对8例患者的10例疝气病变进行了环形切口TAPP,对13例患者的17例病变使用了HPIA的TAPP。HPIA单侧疝的平均手术时间(137.8±20.7分钟)明显短于圆形切口TAPP的(182.2±42.0分钟)(p=.038)。所有患者的HPIA都完成了,5例患者将圆形切口TAPP转换为腹膜内嵌网(IPOM)腹膜内嵌网(55.6%,p=.008),由于粘连致密,解剖困难。随访48个月后,两组均未出现复发。
    结论:对于RARP术后腹股沟疝患者,TAPP联合HPIA是可行的,是一种安全可靠的选择。
    BACKGROUND: Inguinal hernia develops as one of the common complications after robotic or laparoscopic radical prostatectomy (RP). Transabdominal preperitoneal patch plasty (TAPP) for an inguinal hernia after RP is difficult to perform due to postoperative severe adhesions in the preperitoneal cavity. We have introduced a high peritoneal incision approach (HPIA) in TAPP for inguinal hernia patients in whom peritoneal dissection is difficult due to severe adhesions after RP. We evaluate the safety and efficacy of TAPP with a HPIA for patients with an inguinal hernia after robot-assisted RP (RARP).
    METHODS: Patients characteristics and surgical outcome were evaluated by a retrospective analysis.
    RESULTS: From January 2014 to December 2017, 21 consecutive patients underwent TAPP for an inguinal hernia after RARP. Twenty-four lesions were the type 3b and three were type 3a according to the Nyhus classification. A circular incision TAPP was performed for 10 hernia lesions in eight patients and TAPP with HPIA was utilized for 17 lesions in 13 patients. The mean operation time for the unilateral hernia in the HPIA (137.8 ± 20.7 min) was significantly shorter than that (182.2 ± 42.0 min) in the circular incision TAPP (p = .038). The HPIA was complete in all patients, while the circular incision TAPP was converted to intraperitoneal onlay mesh (IPOM)intraperitoneal onlay mesh in five patients (55.6%, p = .008) due to dense adhesions with difficult dissection. No recurrent was observed after follow-up period of 48 months in both groups.
    CONCLUSIONS: The TAPP with HPIA is feasible and a safe and reliable treatment of choice in patients with an inguinal hernia after RARP.
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  • 文章类型: Journal Article
    许多腹部-骨盆手术使用不沿着白线的切口,如横向,腹腔镜,造口术逆转,或造口术形成切口。腹侧切口疝(VIH)在这些部位的患病率以及预防性网片预防VIH的疗效尚不清楚。
    PubMed,Embase,Scopus,和Cochrane数据库从开始到2022年9月进行了系统审查。我们纳入了已发表的随机对照试验(RCT),比较了预防性网状物加固与无网状物。主要结果是术后随访等于或大于24个月时VIH的发生率。次要结果包括手术部位感染(SSI)和手术部位发生(SSO)。
    在3186篇筛选的文章中,只有3个RCT至少有80%的2年随访,共有901名患者,纳入非中线VIH分析。另外15个RCT纳入次要结局分析。预防性网片的造口旁疝发生率为21%,而对照组为44%-64%。预防性网片造口术后切口疝的发生率为10%,对照组为16%。没有明确的证据表明两组之间的SSI或SSO发生率存在差异。
    关于预防性网状物在预防非中线VIH中的作用的证据有限。需要更多低偏倚风险的研究来阐明非中线切口预防性网状物的长期风险和益处的平衡。
    UNASSIGNED: Many abdominal-pelvic surgeries utilize incisions not along the linea alba, such as transverse, laparoscopic, ostomy reversal, or ostomy formation incisions. The prevalence of ventral incisional hernias (VIH) at these sites and the efficacy of prophylactic mesh in preventing VIH remains unclear.
    UNASSIGNED: PubMed, Embase, Scopus, and Cochrane databases were systematically reviewed from inception to September 2022. We included published randomized controlled trials (RCTs) that compared prophylactic mesh reinforcement versus no mesh. The primary outcome was the incidence of VIH at postoperative follow-up equal to or greater than 24 months. Secondary outcomes included surgical site infection (SSI) and surgical site occurrence (SSO).
    UNASSIGNED: Of 3186 screened articles, only 3 RCTs with at least an 80% 2-year follow-up, encompassing a total of 901 patients, were included for analysis of non-midline VIH. Fifteen additional RCTs were included for analysis of secondary outcomes. The rate of parastomal hernias with prophylactic mesh was 21%, while it ranged from 44%-64% in the control group. The rate of incisional hernia after ostomy reversal with prophylactic mesh was 10%, and 16% in the control group. No clear evidence of a difference was found in rates of SSI or SSO between groups.
    UNASSIGNED: There is limited evidence on the role of prophylactic mesh in preventing non-midline VIH. More studies at low risk for bias are needed to elucidate the balance of the long-term risks and benefits of prophylactic mesh for non-midline incisions.
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  • 文章类型: Comparative Study
    背景:当肠的一部分通过腹肌突出时,就会发生腹股沟疝。在成年人中,男性比女性更容易患这种常见病。腹股沟疝可以通过“观察等待”进行监测,但如果症状持续或恶化,通常需要手术,可以是开放式或腹腔镜。成人腹股沟疝的腹腔镜(锁孔)修复通常使用经腹腹膜前(TAPP)或完全腹膜外(TEP)方法进行。两种方法都包括使用放置在腹壁腹膜衬里前面的网片,但是对于TAPP技术,需要进入腹腔放置网孔,对于TEP技术,整个过程是在腹壁的腹膜衬里外侧进行的。一种方法是否优于另一种方法尚未确定,关于它们的相对好处和危害存在争议。TEP的一个优点是它避免了腹腔;缺点是它需要临床医生更陡峭的学习曲线。TAPP被认为更简单,可以检查对侧,但与TEP相比,TAPP可能有更高的内脏损伤风险.这是对2005年首次发布的Cochrane评论的更新。
    目的:比较腹腔镜TAPP技术与腹腔镜TEP技术在成人腹股沟疝修补术中的利弊。
    方法:2022年10月25日,作者在Cochrane图书馆搜索了Cochrane中央对照试验注册中心(CENTRAL);OvidMEDLINE(R)Epub在打印前,过程中和其他非索引引文,OvidMEDLINE(R)日报,和OvidMEDLINE(R);和OvidEmbase,已发表的随机对照试验。为了确定正在进行的研究,我们检索了ClinicalTrials.gov和WHO国际临床试验注册平台(ICTRP).
    方法:所有前瞻性随机,准随机化,将腹腔镜TAPP技术与腹腔镜TEP技术在成人腹股沟疝修补术中进行比较的成群随机试验也符合纳入标准.如果我们可以提取腹股沟疝的数据,我们包括涉及不同类型腹股沟疝的混合研究。研究还可能包括一组通过开放手术接受疝气修复的参与者,但这些组不包括在我们的审查中。
    方法:两位综述作者独立评估了试验资格,从纳入的研究中提取数据,并评估纳入研究的偏倚风险。审查的主要结果是严重不良事件,慢性疼痛(手术后至少持续六个月),和疝气复发。我们还评估了围手术期的各种次要结局,术后早期,和术后晚期时间点。我们使用随机效应模型进行了统计分析,并将结果表示为二分结果的比值比(OR)和连续结果的平均差(MD),与他们各自的95%置信区间(CI)。我们使用等级来评估关键结果的证据的确定性,中度,低或非常低。
    结果:我们在本综述更新中纳入了23项研究,将1156人随机分配给TAPP,将1110人随机分配给TEP,都需要腹股沟疝的修复.研究样本量从40到316不等。绝大多数研究参与者是男性。我们认为大多数研究存在“高”或“不清楚”的偏倚风险。对于我们评估的所有结果,我们对证据确定性的判断都很低或很低。TAPP和TEP腹腔镜技术在严重不良事件方面可能几乎没有差异(0.4%对0.7%;OR0.58,95%CI0.15至2.32,P=0.45,I2=0%;19项研究,1735名参与者;证据确定性低);和疝气复发(1.2%对1.1%;OR1.14,95%CI0.49至2.62,P=0.97,I2=0%;17项研究,1712名参与者;证据确定性低)。关于TAPP与TEP技术对慢性疼痛的影响的证据非常不确定(OR0.62,95%CI0.20至1.97,P=0.68,I2=0%;6项研究,860名参与者;证据确定性非常低)。就次要结果而言,TAPP与TEP技术治疗围手术期内脏和血管损伤的证据非常不确定(15项研究,1523名参与者;证据的确定性非常低),以及术后早期(≤30天)的血肿或血清肿(OR0.86,95%CI0.54至1.37,P=0.3861,I2=0%;15项研究,1423名参与者;证据的确定性非常低)。与TAPP相比,TEP技术转换为另一种疝修补术(TAPP技术或开放手术)的风险更高(2.5%对0.7%;OR0.28,95%CI0.09至0.84,P=0.02,I2=0%;13项研究,1178名参与者;证据确定性低)。只有两项研究(474名参与者)报告了术后晚期(>30天)的生活质量;总体而言,从术前到术后评估,生活质量有所改善,但证据表明技术之间几乎没有差异(证据的确定性低)。
    结论:本综述更新发现,TAPP和TEP技术在严重不良事件方面可能几乎没有差异,疝气复发,或慢性疼痛(低到非常低的确定性证据)。关于使用哪种方法的决定将最有可能反映外科医生和患者的偏好,直到获得高确定性证据。与需要从TAPP转换为开放手术的风险相比,需要从TEP转换为TAPP或开放手术的风险可能更高(低确定性证据)。如果外科医生选择TEP作为他们的标准腹腔镜方法,他们可以考虑有一个策略来处理潜在的转换需求。这可能包括对TAPP方法的熟练程度或已告知患者转换为开放手术的风险。对于外科医生或外科部门来说,腹腔镜技术的选择应涉及患者及其家属或护理人员的共同决策.未来的研究可能集中在患者报告的结果上,比如生活质量。
    BACKGROUND: An inguinal hernia occurs when part of the intestine protrudes through the abdominal muscles. In adults, this common condition is much more likely in men than in women. Inguinal hernia can be monitored by \'watchful waiting\', but if symptoms persist or worsen, surgery is usually required, which can be open or laparoscopic. Laparoscopic (keyhole) repair of inguinal hernias in adults is generally performed using either the transabdominal preperitoneal (TAPP) or the totally extraperitoneal (TEP) method. Both methods include the use of mesh placed in front of the peritoneal lining of the abdominal wall, but for the TAPP technique, the abdominal cavity needs to be entered to place the mesh, and for the TEP technique, the whole procedure is done on the outside of the peritoneal lining of the abdominall wall. Whether one method is superior to the other has not been established, and there is debate about their relative benefits and harms. An advantage of TEP is its avoidance of the abdominal cavity; the downside is that it requires a steeper learning curve for clinicians. TAPP is considered simpler and makes it possible to inspect the contralateral side, but TAPP may have a higher risk of visceral injury compared to TEP. This is an update of a Cochrane review first published in 2005.
    OBJECTIVE: To compare the benefits and harms of laparoscopic TAPP technique versus laparoscopic TEP technique for inguinal hernia repair in adults.
    METHODS: On 25 October 2022, the authors searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library; Ovid MEDLINE(R) Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily, and Ovid MEDLINE(R); and Ovid Embase, for published randomised controlled trials. To identify studies in progress, we searched ClinicalTrials.gov and the WHO International Clinical Trial Registry Platform (ICTRP).
    METHODS: All prospective randomised, quasi-randomised, and cluster-randomised trials that compared the laparoscopic TAPP technique with the laparoscopic TEP technique for inguinal hernia repair in adults were eligible for inclusion. We included studies that involved a mix of different types of groin hernia if we could extract data for the inguinal hernias. Studies may have also included a group of participants receiving hernia repair by open surgery, but these groups were not included in our review.
    METHODS: Both review authors independently evaluated trial eligibility, extracted data from included studies, and assessed the risk of bias in the included studies. The review\'s primary outcomes were serious adverse events, chronic pain (persisting for at least six months after surgery), and hernia recurrence. We also assessed a variety of secondary outcomes at perioperative, early postoperative, and late postoperative time points. We performed statistical analyses using the random-effects model, and expressed the results as odds ratios (ORs) for dichotomous outcomes and mean differences (MDs) for continuous outcomes, with their respective 95% confidence intervals (CIs). We used GRADE to assess the certainty of evidence for key outcomes as high, moderate, low or very low.
    RESULTS: We included 23 studies in this review update, which randomised 1156 people to TAPP and 1110 people to TEP, all requiring repair of inguinal hernias. Study sample sizes varied from 40 to 316 participants. The vast majority of study participants were male. We judged most studies to be at \'high\' or \'unclear\' risk of bias. Our judgements of the certainty of the evidence were low or very low for all outcomes we assessed. There may be little to no difference between TAPP and TEP laparoscopic techniques for serious adverse events (0.4% versus 0.7%; OR 0.58, 95% CI 0.15 to 2.32, P = 0.45, I2 = 0%; 19 studies, 1735 participants; low certainty of evidence); and hernia recurrence (1.2% versus 1.1%; OR 1.14, 95% CI 0.49 to 2.62, P = 0.97, I2 = 0%; 17 studies, 1712 participants; low certainty of evidence). The evidence is very uncertain about the effects of TAPP versus TEP techniques on chronic pain (OR 0.62, 95% CI 0.20 to 1.97, P = 0.68, I2 = 0%; 6 studies, 860 participants; very low certainty of evidence). In terms of secondary outcomes, the evidence is very uncertain for TAPP versus TEP techniques for perioperative visceral and vascular injury (15 studies, 1523 participants; very low certainty of evidence), and for haematoma or seroma during the early (≤ 30 days) postoperative phase (OR 0.86, 95% CI 0.54 to 1.37, P = 0.3861, I2 = 0%; 15 studies, 1423 participants; very low certainty of evidence). TEP technique may carry a higher risk of conversion to another hernia repair method (either TAPP technique or open surgery) when compared to TAPP (2.5% versus 0.7%; OR 0.28, 95% CI 0.09 to 0.84, P = 0.02, I2 = 0%; 13 studies, 1178 participants; low certainty of evidence). Only two studies (474 participants) reported quality of life in the late (> 30 days) postoperative phase; overall, there was an improvement in quality of life from the pre- to post-operative assessment, but the evidence suggests little to no difference between the techniques (low certainty of evidence).
    CONCLUSIONS: This review update found that there may be little to no difference between the TAPP and TEP techniques for serious adverse events, hernia recurrence, or chronic pain (low- to very-low-certainty evidence). Decisions about which method to use will most likely reflect surgeon and patient preference until high-certainty evidence becomes available. There may be a higher risk of needing to convert from TEP to TAPP or open surgery when compared to the risk of needing to convert from TAPP to open surgery (low-certainty evidence). If surgeons opt for TEP as their standard laparoscopic method, they could consider having a strategy for how to handle the potential need for conversion. This might include proficiency in the TAPP approach or having informed the patient about the risk of conversion to open surgery. For surgeons or surgical departments, the choice of a laparoscopic technique should involve shared decision-making with patients and their families or carers. Future research could focus on patient-reported outcomes, such as quality of life.
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  • 文章类型: Journal Article
    目的:我们旨在评估切口疝修补术后术后前30天的手术伤口并发症对患者长期生活质量的影响。此外,还将评估手术技术和术前合并症对患者生活质量的影响.
    方法:前瞻性队列研究,该研究使用onlay和后肌技术评估了2019年至2020年间接受切口疝修补术的115例患者。这些患者最初在术后前30天评估手术伤口结果(手术部位感染(SSI)或手术部位发生(SSO))。然后,三年后评估,通过一份特定的生活质量问卷,疝相关生活质量调查(HerQLes)。
    结果:一些患者在研究期间失去随访,由于死亡,接触困难,拒绝回答问卷,对80例患者进行了评估。其中,11例患者(13.8%)在术后前30天有SSI,37例(46.3%)有某种类型的SSO。未发现SSI和SSO对生活质量指数的影响。在分析其他变量时,我们观察到体重指数(BMI)对患者的生活质量有显著影响.同样,疝大小和网孔大小被确定为与较差生活质量结局相关的变量.在使用的手术技术方面没有观察到差异。
    结论:在本研究中,使用HerQLes评分未发现手术伤口结局(SSO和SSI)与较差的生活质量结果之间的关系.我们观察到BMI以及网眼和疝气的大小与生活质量指数呈成反比关系。然而,应开展更多的研究评估术前生活质量指数,并将其与术后指标进行比较,以评估这些相关性。
    OBJECTIVE: We aim to evaluate the impact of surgical wound complications in the first 30 postoperative days after incisional hernia repair on the long-term quality of life of patients. In addition, the impact of the surgical technique and preoperative comorbidities on the quality of life of patients will also be evaluated.
    METHODS: Prospective cohort study, which evaluates 115 patients who underwent incisional hernioplasty between 2019 and 2020, using the onlay and retromuscular techniques. These patients were initially assessed with regard to surgical wound outcomes in the first 30 postoperative days (surgical site infection (SSI) or surgical site occurrence (SSO)), and then, assessed after three years, through a specific quality of life questionnaire, the Hernia Related Quality of Life Survey (HerQLes).
    RESULTS: After some patients were lost to follow-up during the study period, due to death, difficulty in contact, refusal to respond to the questionnaire, eighty patients were evaluated. Of these, 11 patients (13.8%) had SSI in the first 30 postoperative days and 37 (46.3%) had some type of SSO. The impact of both SSI and SSO on quality of life indices was not identified. When analyzing others variables, we observed that the Body Mass Index (BMI) had a significant impact on the patients\' quality of life. Likewise, hernia size and mesh size were identified as variables related to a worse quality of life outcome. No difference was observed regarding the surgical techniques used.
    CONCLUSIONS: In the present study, no relationship was identified between surgical wound outcomes (SSO and SSI) and worse quality of life results using the HerQLes score. We observed that both BMI and the size of meshes and hernias showed an inversely proportional relationship with quality of life indices. However, more studies evaluating preoperative quality of life indices and comparing them with postoperative indices should be carried out to evaluate these correlations.
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  • 文章类型: Case Reports
    我们介绍了一例复发性腹股沟膀胱疝的病例,该病例先前三次手术均未成功,并使用完全腹膜外修复(TEP)进行了修复。一名79岁的男子出现右腹股沟肿胀,在同一侧用前路手术治疗了三次。计算机断层扫描证实腹股沟膀胱疝复发。在术前确定膀胱疝后进行TEP,与以前的手术使用的是通过前路插入和修补技术。腹膜外方法允许膀胱减少而不受伤,并使用3DMax®LightMesh安全修复疝气。术后恢复顺利,1年后无复发。TEP有助于膀胱疝的诊断和修复,强调术前诊断的重要性和内镜下膀胱疝修补术的疗效,即使在复发病例中。
    We present a case of a recurrent inguinal bladder hernia that was previously unsuccessfully operated on three times and was repaired using totally extraperitoneal repair (TEP). A 79-year-old man presented with a right inguinal swelling that had been treated three times on the same side with anterior approaches. Computed tomography confirmed a recurrent inguinal bladder hernia. TEP was performed after identifying the bladder hernia preoperatively, with previous surgeries that used a plug-and-patch technique through an anterior approach. The extraperitoneal approach allowed the bladder to be reduced without injury and the hernia to be safely repaired using a 3D Max® Light Mesh. The postoperative recovery was uneventful, with no recurrence after 1 year. TEP facilitates the diagnosis and repair of bladder hernias, emphasizing the importance of preoperative diagnosis and the efficacy of endoscopic procedures in bladder hernia repair, even in recurrent cases.
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  • 文章类型: Journal Article
    背景:腹侧疝修补术是一种常见的选择性外科手术,缺乏明确的手术方法。这项研究旨在评估腹部疝的初次缝合修复或聚丙烯夹心网修复的效果。主要结局指标为疝复发率,并评估长期并发症和患者报告的结局。
    方法:这项回顾性队列研究评估了原发性腹侧疝(上腹部,上脐带,或脐带)修补或小(≤20mm)中线切口疝修补术后10年。短期随访发生在最初手术后6周,而长期随访包括在手术后3年或超过3年时接受临床审查或电话访问的患者.
    结果:大多数(75/100,75.0%)患者进行了腹膜外夹心网片修复。短期随访显示所有患者疼痛轻微,活动正常(97/97,100%)。95.9%(93/97)的患者获得了长期随访(中位数12年[IQR11-13]),只有少数患者报告了轻微的隆起(5/93,5.4%)和间歇性轻度不适(8/93,8.6%)。9例患者(9/97,9.3%)出现疝气复发,诊断中位数为26个月[四分位距,IQR,7-58]术后。
    结论:这些研究结果表明,开放式夹心网片技术是修复原发性腹侧疝和小中线切口疝的一种安全有效的方法,并且与患者报告的长期预后良好相关。
    BACKGROUND: Ventral hernia repair is a common elective surgical procedure lacking strong evidence for specific operative approaches. This study aimed to evaluate the outcomes of primary suture repair or polypropylene sandwich mesh repair for ventral hernias. The main outcome measures were the rate of hernia recurrence, and evaluation of long-term complications and patient-reported outcomes.
    METHODS: This retrospective cohort study evaluated patient perceived recurrence and pain in patients who had undergone a primary ventral hernia (epigastric, supraumbilical, or umbilical) repair or small (≤20 mm) midline incisional hernia repair 10 years after the procedure. Short-term follow-up occurred up to 6 weeks after the initial operation, while long-term follow-up included patients who were reviewed clinically or interviewed via telephone at or beyond 3 years after the procedure.
    RESULTS: Most (75/100, 75.0%) patients had an extra-peritoneal sandwich mesh repair. Short-term follow-up showed minimal pain and normal activities for all patients (97/97, 100%). Long-term follow-up (median 12 years [IQR 11-13]) was achieved in 95.9% (93/97) of patients with only a small number reporting a slight bulge (5/93, 5.4%) and intermittent mild discomfort (8/93, 8.6%). Nine patients (9/97, 9.3%) experienced hernia recurrence, diagnosed at a median of 26 months [interquartile range, IQR, 7-58] post-operatively.
    CONCLUSIONS: These findings suggest that an open sandwich mesh technique is a safe and effective method for repairing primary ventral hernias and small midline incisional hernias and is associated with favourable long-term patient-reported outcomes.
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  • 文章类型: Case Reports
    大型腹侧疝需要复杂的手术技术,如组件分离。我们正在介绍一例15×8厘米的切口疝。疝气覆盖有上覆的薄层皮肤和疝气囊。该层的皮肤紧密粘附在下面的疝囊上。由于薄的疝囊和皮肤的粘附性,保留了约3厘米的疝囊。我们使用这个疝囊作为前鞘“延伸”无张力闭合。进行腹横肌释放的后部组件分离,以在没有张力的情况下关闭后部层,并在直肌后平面上放置23×16cm的网格。通过使用疝囊修复,我们避免了前组件分离,实现了前层无张力闭合.
    Large ventral hernias require complex surgical techniques, such as component separation. We are presenting a case of an incisional hernia measuring 15×8 cm. The hernia was covered with an overlying thin layer of skin and hernia sac. The skin of this layer was densely adherent to the underlying hernial sac. Because of the thin hernial sac and adherent nature of the skin, approximately 3 cm of the hernial sac was preserved. We used this hernial sac as the anterior sheath \'extension\' for a tension-free closure. Posterior component separation with transverse abdominis muscle release was done to close the posterior layer without tension and to place a 23×16 cm mesh in the retrorectus plane. By using the hernial sac in repair, we avoided anterior component separation and achieved tension-free closure of the anterior layer.
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  • 文章类型: Journal Article
    目的:我们研究了菠萝蛋白酶(200mg)和BoswelliaserrataCasperome®(200mg)的营养组合对网片疝修补术术后结果的潜在益处。
    方法:一百八十位患者(27位女性,153名男性)被招募使用Progrim®进行开放式无张力疝修补术。患者被随机分配为空腹接受一片Siben®(研究组)或安慰剂(对照组)。术后11天,每12小时一次。所有患者都填写了针对术后疼痛的医学问卷,基于视觉模拟量表(VAS)量表和简短表格36(SF-36)问卷,在时间T0(手术日)和T28(手术后第28天)。
    结果:一年的结果显示研究组的主要术后转归有显著改善。与对照组相比,Siben®组的疼痛感知显著降低,术后第7天(p<0.05)和第21天(p<0.05)。包括在Siben®组中的患者也比对照更早地恢复日常活动并恢复工作。此外,SF-36的结果表明,研究组的生活质量(QoL)评分优于安慰剂组.
    结论:我们的分析有效地表明,在开放式腹股沟疝网片修补术中使用Siben®可以改善短期和长期手术结果,有助于更好的QoL。
    OBJECTIVE: We investigated the potential benefits of administering a nutraceutical combination of Bromelain (200 mg) and Boswellia serrata Casperome® (200 mg) on post-operative outcomes of hernioplasty with mesh.
    METHODS: One hundred eighty patients (27 females, 153 males) were enrolled to undergo open tension-free hernioplasty with the use of Progrip®. Patients were randomized to receive either one tablet of Siben® (study group) or placebo (control group) on an empty stomach, every twelve hours for eleven postoperative days. All patients filled out a medical questionnaire focused on postoperative pain, based on the Visual Analogue Scale (VAS) scale and the Short Form-36 (SF-36) questionnaire, at time T0 (day of surgery) and T28 (28th day after surgery).
    RESULTS: One-year results showed a significant improvement in the primary postoperative outcome in the study group. Perception of pain was significantly reduced in the Siben® group compared with controls, both on the seventh (p < 0.05) and the twenty-first (p < 0.05) postoperative day. Patients included in the Siben® group also resumed daily activities and returned to work earlier than the controls. Moreover, results of the SF-36 indicated better Quality of Life (QoL) scores in the study group compared to the placebo group.
    CONCLUSIONS: Our analysis effectively demonstrates that the use of Siben® in open inguinal hernia mesh repair may improve short- and long-term surgical outcomes, contributing to a better QoL.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Case Reports
    一名60多岁的妇女因痛苦而被送往急诊科,左肩深疼痛,被发现患有右侧Morgagni疝,一种罕见类型的先天性膈疝(CDH)。她没有胸痛,心悸,呼吸急促,咳嗽,腹痛,便秘,腹泻,恶心,呕吐或其他与成人CDHs相关的症状。进行了腹腔镜机器人辅助修复与网状物放置,病人的康复并不复杂,无肩痛复发。我们的患者的表现是不寻常的,因为没有典型的成人CDHs症状,对侧的存在,左侧肩痛伴右侧Morgagni疝.
    A woman in her 60s presented to the emergency department with excruciating, deep left shoulder pain and was found to have a right-sided Morgagni hernia, a rare type of congenital diaphragmatic hernia (CDH). She did not have chest pain, palpitations, shortness of breath, cough, abdominal pain, constipation, diarrhoea, nausea, vomiting or other symptoms classically associated with CDHs in adults. Laparoscopic robotic-assisted repair with mesh placement was performed, and the patient\'s recovery was uncomplicated, with no recurrence of shoulder pain. Our patient\'s presentation was unusual due to the absence of symptoms typically seen with CDHs in adults, and the presence of contralateral, left-sided shoulder pain with a right-sided Morgagni hernia.
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