neck

颈部
  • 文章类型: Journal Article
    Subcutaneous emphysema is a relatively harmless finding which is pathognomonic for a mid-facial fracture in most cases. Increasing pressure will cause air to expand beyond the tissues. It is often caused by blowing one\'s nose, but can also result from intubation in cases of more severe trauma. Crepitus can be heard or felt subcutaneously upon palpitation. Two cases of patients presenting at an oral and maxillofacial unit with extensive emphysema in the head and neck region illustrate both a common and an unusual cause.
    Subcutaan emfyseem is een relatief onschuldige bevinding, die in de meeste gevallen pathognomisch is bij een breuk in het middengezicht. Door een toename van druk zal lucht buiten de weefsels treden. Veelal komt dit door snuiten van de neus, maar bij ernstiger traumatisch letsel kan het ook ontstaan bij intubatie. Bij palpatie kan onderhuids een crepiterend geluid gehoord of gevoeld worden. Twee casussen van patiënten die zich presenteerden op een MKA-afdeling met een uitgebreid emfyseem in het hoofd-halsgebied illustreren een veelvoorkomende én een bijzondere oorzaak.
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  • 文章类型: Journal Article
    目标:颈深间隙感染(DNSI),由牙源性感染扩散到口腔和颈部底部引起的,可能会危及生命,但可以预防。我们探讨了牙源性DNSI患者的疾病总成本(COI)。
    方法:横截面,基于寄存器,DNSI治疗健康经济学的多中心研究。包括年龄>18岁的患者,他们在医院接受牙源性DNSI治疗。根据国际疾病分类(ICD)代码和手术程序代码,从区域医疗保健数据库VEGA中确定受试者。医院护理的每位患者成本(CPP)值,提取处方药和病假。
    结果:总计,148名患者被包括在内。平均住院时间为6天。估计每位患者的总COI为15,400欧元,总计2,280,000欧元。直接成本占COI的93%,间接成本为7%。
    结论:牙源性DNSI患者的总COI比耳鼻咽喉科(ORL)护理患者的平均COI高六倍。预防DNSI将为专业医疗保健单位节省大量成本,并将对患者产生重大影响。
    OBJECTIVE: Deep neck space infections (DNSI), caused by the spread of an odontogenic infection to the floor of the mouth and neck, are potentially life-threatening but preventable. We explored the total cost of illness (COI) for patients with DNSI of odontogenic origin.
    METHODS: Cross-sectional, register-based, multi-centre study of the health economics of DNSI treatment. Included were patients aged > 18 years who were treated in hospital for DNSI of odontogenic origin. Subjects were identified from the regional healthcare database VEGA based on the International Classification of Diseases (ICD) codes and surgical procedure codes. The cost per patient (CPP) values for the hospital care, prescription medications and sick leave were extracted.
    RESULTS: In total, 148 patients were included. The average length of the hospital stay was 6 days. Total COI was estimated as 15,400 EUR per patient and 2,280,000 EUR in total. Direct costs accounted for 93% of the COI, and indirect costs were 7%.
    CONCLUSIONS: The total COI for patients with DNSI of odontogenic origin was six-fold higher than the average COI for patients in otorhinolaryngology (ORL) care. Preventing DNSI will entail substantial cost savings for the specialised healthcare units and will have a significant impact on the patients.
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  • 文章类型: Journal Article
    背景:泛菌为革兰氏阴性,需氧/兼性厌氧,杆状杆菌通常从植物中分离出来,土壤,食物和粪便。(1)它是人类机会性感染的罕见原因,主要通过两条主要途径获得,伤口感染或医院获得性感染。
    方法:这里,我们遇到了一个里程碑,第一个同类,宫颈软组织脓肿的头颈部表现,其中Pantoea团块是畸形。患者出现左侧颈部肿胀的抱怨,放射学上暗示是冷脓肿,然而,临床复苏鼓励我们进行切口和引流,其培养物揭示了这种臭名昭著的植物性细菌。
    结论:文献中记载的常见泛菌感染病例显示了眼内炎的临床表现,急性单侧泪囊炎,骨膜炎,心内膜炎,骨髓炎和大腿肌肉囊肿等肿瘤,其中许多最终导致败血症,而少数还使用靶向抗生素解决。(2)值得注意的是,迄今为止,文献中还没有文献报道耳鼻喉或头颈部表现.回顾性证实了刷芒果树的外伤史,这被发现是拼图中缺失的一块。
    BACKGROUND: Pantoea agglomerans is a gram negative, aerobic/facultative anaerobic, rod shaped bacilli commonly isolated from plants, soil, food and faeces.(1) It is a rare cause of opportunistic infections in humans acquired mainly via two major routes being, wound infection or hospital acquired.
    METHODS: Here, we encountered a landmark, first of its kind, head and neck manifestation of a cervical soft tissue abscess with Pantoea agglomerans being the miscreant. The patient presented with complaints of a left sided neck swelling, which was radiologically suggestive of a cold abscess, however clinical suscpicion encouraged us to perform an incision and drainage, culture of which revealed this notorious phytogenic bacterium.
    CONCLUSIONS: Commonly encountered Pantoea infected cases documented in literature have shown a clinical picture of endophthalmitis, acute unilateral dacryocystitis, periostitis, endocarditis, osteomyelitis and a tumour like muscle cyst of the thigh with many of them eventually leading to septicemia while a few also resolved with targeted antibiotics.(2) Remarkably, no ENT or head and neck presentations have been reported in literature till date. History of trauma by brushing against a mango tree was confirmed retrospectively, which was found to be the missing piece of the puzzle.
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  • 文章类型: Journal Article
    目的:回顾运动干预对运动相关脑震荡(SRC)发生率的影响,以及线性和旋转头部加速度,和等距颈部力量,并使用运动报告模板共识(CERT)评估运动干预措施的报告完整性。
    方法:系统评价和荟萃分析,根据《锻炼中的棱镜》,康复,运动医学和孢子科学指南。
    方法:六个数据库(MEDLINE,Embase,CINAHL,Scopus,WebofScienceCC和SPORTDiscus)进行了搜索,直到2023年6月26日。
    方法:随机对照试验(RCT),集群随机对照试验或准实验研究,评估运动干预对SRC发病率的影响,线性和旋转头部加速度,和/或任何年龄的男性和/或女性运动员的等距颈部力量,和/或在健康的普通人群中。
    结果:共纳入26篇。阻力训练(RT)对等距颈部力量的影响很大(标准化平均差(SMD)0.85;95%CI0.57至1.13;高质量证据)。神经肌肉热身计划对SRC发生率的影响不显著(风险比0.69;95%CI0.39至1.23;低质量证据),或对于头部线性加速度(SMD-0.43;95%CI-1.26至0.40;极低质量证据)或头部旋转加速度(SMD0.08;95%CI-0.61至0.77;低质量证据)。没有研究评估RT对SRC发生率的影响。CERT评分范围从4到16(共19分),中位数为11.5(IQR9-13)。
    结论:RT增加了等距颈部强度,但对SRC发病率的影响尚不清楚。需要更充分和严格的试验来评估运动干预对SRC发生率的影响。以及线性和旋转头部加速度。未来的研究应遵循CERT指南,因为纳入的干预措施通常没有足够详细地报告,无法准确复制.
    CRD42023435033。
    OBJECTIVE: To review the efficacy of exercise interventions on sport-related concussion (SRC) incidence, as well as on linear and rotational head accelerations, and isometric neck strength and to assess reporting completeness of exercise interventions using the Consensus on Exercise Reporting Template (CERT).
    METHODS: Systematic review and meta-analysis, according to the Prisma in Exercise, Rehabilitation, Sport medicine and SporTs science guidelines.
    METHODS: Six databases (MEDLINE, Embase, CINAHL, Scopus, Web of Science CC and SPORTDiscus) were searched up to 26 June 2023.
    METHODS: Randomised controlled trials (RCTs), cluster RCTs or quasi-experimental studies, evaluating exercise interventions on SRC incidence, linear and rotational head accelerations, and/or isometric neck strength in male and/or female athletes of any age, and/or in a healthy general population.
    RESULTS: A total of 26 articles were included. A large effect size was observed for resistance training (RT) on isometric neck strength (standardised mean difference (SMD) 0.85; 95% CI 0.57 to 1.13; high-quality evidence). Non-significant effect sizes were observed for neuromuscular warm-up programmes on SRC incidence (risk ratio 0.69; 95% CI 0.39 to 1.23; low-quality evidence), or for RT on linear head acceleration (SMD -0.43; 95% CI -1.26 to 0.40; very low-quality evidence) or rotational head acceleration (SMD 0.08; 95% CI -0.61 to 0.77; low-quality evidence). No studies assessed the impact of RT on SRC incidence. CERT scores ranged from 4 to 16 (out of 19) with median score of 11.5 (IQR 9-13).
    CONCLUSIONS: RT increases isometric neck strength, but the effect on SRC incidence is unknown. More adequately powered and rigorous trials are needed to evaluate the effect of exercise interventions on SRC incidence, and on linear and rotational head accelerations. Future studies should follow CERT guidelines, as the included interventions were generally not reported in sufficient detail for accurate replication.
    UNASSIGNED: CRD42023435033.
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  • 文章类型: Journal Article
    紧急颈前通路是指通过颈前结构将氧气输送到气道管腔中的所有技术,包括通过环甲膜和气管壁的通路。关于首选技术尚未达成普遍协议。手术切口是目前院前和院内护理中最常见的方法。本综述旨在回顾和总结现有的临床,基础科学,以及eFONA的社会指南。
    Emergency front-of-neck access refers to all techniques that deliver oxygen into the airway lumen through the anterior neck structures and encompasses access both through the cricothyroid membrane and the tracheal wall. There has yet to be a universal agreement regarding the preferred technique. A surgical incision is currently the most common approach in prehospital and in-hospital care. This review intends to review and summarize the existing clinical, basic science, and societal guidelines for eFONA.
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  • 文章类型: Journal Article
    背景:非特异性颈痛(NSNP)是一种公认的全球性负担。这在巴基斯坦也是一个普遍的问题。由于人体工程学差,颈部疼痛的负担也日益增加,以及大流行后电脑和手机的使用增加。个人的不良姿势通常与前头部姿势(FHP)有关。关于颈部稳定(NSE)和动态运动(NDE)对非特异性颈部疼痛的影响的证据有限,尤其是在FHP患者中。本研究旨在比较NSE与NDE在NSNP与FHP患者中减轻疼痛的效果。残疾,向前的头部姿势和改善颈部的运动范围。
    方法:这是一项单盲随机临床试验,纳入60名年龄在18-40岁的患者,中等强度NSNP持续>3周和<6个月,同时FHP伴有中度残疾的颈部残疾指数(NDI)随机分配到治疗组。第1组进行NSE,第2组进行NDE。经皮电刺激,冷包,两组都进行了伸展运动。与会者共举行了9次会议(每周3次会议)。NDI问卷,视觉模拟量表(VAS)测角,和铅垂线测量工具用作基线,并在第3周末进行评估.数据在SPSS21版上进行分析。进行描述性分析。组间比较采用独立t检验,组内比较采用配对t检验。小于0.05的p值被认为是统计学上显著的。
    结果:治疗后,NSE和NDE的组内分析显示,VAS疼痛显着(p<0.001)改善,颈部的所有ROM,包括屈曲,扩展,左右外侧屈曲和左旋转,铅垂线和NDI得分具有非常大的效果大小。然而,组间分析显示治疗后平均VAS无显著差异(p>0.05),颈部ROM,NDI和铅垂线测量。
    结论:在NSE和NDE之间,没有人比另一个人更有益。两者在减轻疼痛方面同样有效,增加ROM,减少功能障碍,改善NSNP患者的前头部姿势。
    背景:ClinicalTrials.gov标识符:NCT05298631,28/03/2022,前瞻性注册的注册试验。
    BACKGROUND: Nonspecific neck pain (NSNP) is a well-established global burden affecting. It is also a common problem in Pakistan. The burden of neck pain is also increasing day by day due to poor work ergonomics, and increased use of computers and mobiles after the pandemic. An individual\'s poor posture is often associated with forward head posture (FHP). Limited evidence is available about the effects of neck stabilization (NSE) and dynamic exercises (NDE) for nonspecific neck pain particularly in patients with FHP. This aimed to compare the effects of NSE versus NDE among patients having NSNP with FHP in reducing pain, disability, forward head posture and improving neck range of motion.
    METHODS: It is a single-blinded randomized clinical trial with 60 patients aged 18-40 years, with moderate intensity NSNP for > 3 weeks and < 6 months along with FHP with a moderate disability on neck disability index (NDI) randomly assigned to the treatment groups. Group 1 was doing NSE and group 2 was doing NDE. Transcutaneous Electical Nerve Stimulation, cold packs, and stretching exercises were given to both groups. A total of 9 sessions (3 sessions/ week) were given to participants. NDI questionnaire, Visual analogue scale (VAS), goniometry, and plumb line measurement tool were used as baseline and assessment at the end of 3rd week. The data was analyzed on SPSS version 21. Descriptive analysis was performed. Independent t-test was used for between group comparison and paired t-test used for within group comparison. A p-value less than 0.05 was considered statistically significant.
    RESULTS: After treatment within-group analysis of both NSE and NDE showed significant (p < 0.001) improvement in pain on VAS, all ROMs of the neck including flexion, extension, left and right lateral flexion and left rotation, plumb line and NDI score with very large effect size. However, between-group analysis showed non-significant differences (p > 0.05) for post-treatment mean VAS, neck ROM, NDI and plumb line measurement.
    CONCLUSIONS: Between NSE and NDE, no one is more beneficial than another. Both are equally effective in alleviating pain, increasing ROM, decreasing functional disability, and improving forward head posture in patients with NSNP.
    BACKGROUND: Registered trial at ClinicalTrials.gov Identifier: NCT05298631, 28/03/2022, prospectively registered.
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  • 文章类型: English Abstract
    Objective: To explore the risk factors of neck work-related musculoskeletal disorders (WMSDs) among automobile manufacturing enterprise workers, and construct the risk prediction model. Methods: In May 2022, a cluster convenience sampling method was used to selet all front-line workers from an automobile manufacturing factory in Xiangyang City as the research objects. And a questionnaire survey was conducted using the modified Musculoskeletal Disorders Questionnaire to analyze the occurrence and exposure to risk factors of neck WMSDs. Logistic regression was used to analyze the influencing factors of workers\' neck WMSDs symptoms, and Nomogram column charts was used to construct the risk prediction model. The accuracy of the model was evaluated by the receiver operating characteristic (ROC) curve, the Bootstrap resampling method was used to verify the model, Hosmer-Lemeshow goodness of fit test was used to evaluate the model, and the Calibration curve was drawn. Results: A total of 1783 workers were surveyed, and the incidence of neck WMSDs symptoms was 24.8% (442/1783). Univariate logistic regression showed that age, female, smoking, working in uncomfortable postures, repetitive head movement, feeling constantly stressed at work, and completing conflicting tasks in work could increase the risk of neck WMSDs symptoms in automobile manufacturing enterprise workers (OR=1.37, 95%CI: 1.16-1.62; OR=2.85, 95%CI: 1.56-5.20; OR=1.50, 95%CI: 1.18-1.91; OR=1.18, 95%CI: 1.02-1.37; OR=1.34, 95%CI: 1.04-1.72; OR=1.62, 95%CI: 1.21-2.17; OR=1.48, 95%CI: 1.13-1.92; P<0.05). While adequate rest time could reduce the risk of neck WMSDs symptoms (OR=0.56, 95%CI: 0.52-0.86, P<0.05). The risk prediction model of neck WMSDs of workers in automobile manutacturing factory had good prediction efficiency, and the area under the ROC curve was 0.72 (95%CI: 0.70-0.75, P<0.001) . Conclusion: The occurrence of neck WMSDs symptoms of workers in automobile manufacturing factory is relatively high. The risk prediction model constructed in this study can play a certain auxiliary role in predicting neck WMSDs symptoms of workers in automobile manufacturing enterprise workers.
    目的: 探讨汽车制造业工人颈部工作相关肌肉骨骼疾患(WMSDs)的影响因素,并构建风险预测模型。 方法: 于2022年5月,采用方便抽样法,选取襄阳市1家汽车制造厂所有一线工人作为研究对象,采用改良《肌肉骨骼疾患调查问卷》调查其颈部WMSDs症状发生情况及危险因素暴露情况,采用logistic回归分析工人颈部WMSDs症状发生的影响因素,用Nomogram列线图构建风险预测模型。通过受试者工作特征(ROC)曲线评价模型准确性,运用Bootstrap重抽样的方法进行模型验证,Hosmer-Lemeshow拟合优度检验评价模型,绘制校准曲线(Calibration curve)。 结果: 共调查1 783名工人,颈部WMSDs症状发生率为24.8%(442/1 783)。多因素logistic回归分析显示,年龄、女性、吸烟、以不舒服姿势工作、头部重复动作、总是感到工作压力大、完成有矛盾的工作会增加汽车制造业工人颈部WMSDs症状的发生风险(OR=1.37,95%CI:1.16~1.62;OR=2.85,95%CI:1.56~5.20;OR=1.50,95%CI:1.18~1.91;OR=1.18,95%CI:1.02~1.37;OR=1.34,95%CI:1.04~1.72;OR=1.62,95%CI:1.21~2.17;OR=1.48,95%CI:1.13~1.92;P<0.05),而休息时间充足会降低颈部WMSDs症状的发生风险(OR=0.56,95%CI:0.52~0.86,P<0.05)。该汽车制造厂工人颈部WMSDs风险预测模型具有较好的预测效能,ROC曲线下面积(AUC)为0.72(95%CI:0.70~0.75,P<0.001)。 结论: 该汽车制造厂工人颈部WMSDs症状发生率较高,本研究构建的风险预测模型可以对汽车制造业工人颈部WMSDs症状发生起到一定的辅助预测作用。.
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  • 文章类型: Journal Article
    背景:水平颈部皱纹的出现越来越成为美容专业人员和客户的焦点。必须考虑各种治疗方法来有效解决这个问题,由于其不同的根本原因。该研究探讨了将Endolift激光与纳米粒子注射结合使用作为可行的治疗选择的潜力。
    方法:研究涉及20例颈部水平皱纹患者。10例患者接受了Endolift激光和纳米粒子注射联合治疗,10例患者仅接受纳米粒子注射治疗。在治疗后6个月对参与者进行监测。生物识别测量用于评估结果,包括音量的变化,深度,和皱纹区域,皮肤弹性,以及治疗区域表皮和真皮的直径和密度。由两名独立的皮肤科医生评估皮肤改善情况,他们以盲目的方式比较了前后的照片。还记录了患者的满意度水平。
    结果:Visioface分析显示两组的颈部皱纹深度和面积均显著减少。然而,与单独使用纳米脂肪治疗的组相比,接受Endolift激光和纳米脂肪联合治疗的组表现出显著更大的改善.皮肤超声检查结果表明,两组真皮和表皮的厚度和密度均增加。特别是,与仅纳米囊组相比,Endolift激光纳米囊组的真皮和表皮密度和厚度显着提高。用Cutometer分析显示,与仅纳米脂肪治疗组相比,Endolift纳米脂肪治疗组的皮肤弹性显着增强。此外,在Endolift-nanofat治疗组中,绝大多数(90%)患者表现出改善.患者评估强调了两组之间的显着差异,Endolift-nanofat治疗组中95%的患者表现出增强作用。
    结论:两种方法都显着增强了颈部的水平皱纹;尽管如此,内剥离激光和纳米脂肪的组合似乎更有效地治疗水平颈部皱纹。
    BACKGROUND: The emergence of horizontal neck wrinkles is increasingly becoming a focal point for both cosmetic professionals and clients. Various treatment approaches must be considered to address this issue effectively, owing to its diverse underlying causes. The study explores the potential of utilizing the Endolift laser in conjunction with nanofat injection as a viable treatment option.
    METHODS: Twenty patients with horizontal neck wrinkles involved in the study. Ten patients underwent treatment with a combination of Endolift laser and nanofat injection and 10 patients treated with nanofat injection alone. The participants were monitored for 6 months post-treatment. Biometric measurements were utilized to assess outcomes, including changes in volume, depth, and area of the wrinkles, skin elasticity, as well as the diameter and density of the epidermis and dermis in the treated area. Skin improvement was evaluated by two independent dermatologists, who compared before and after photos in a blinded manner. Patient satisfaction levels were also documented.
    RESULTS: The Visioface analysis showed a notable decrease in neck wrinkle depth and area in both groups. However, the group receiving the combination treatment of Endolift laser and nanofat exhibited a significantly greater improvement compared to the group treated with nanofat alone. Skin ultrasonography results demonstrated an increase in thickness and density of the dermis and epidermis in both groups. Particularly, the group treated with Endolift laser-nanofat displayed significant enhancements in dermis and epidermis density and thickness when contrasted with the nanofat-only group. Analysis with Cutometer revealed a marked enhancement in skin elasticity in the Endolift-nanofat treated group in comparison to the nanofat-only treated group. Furthermore, in the Endolift-nanofat treated group, a substantial majority (90%) of patients exhibited improvement. Patient evaluations highlighted significant distinctions between the two groups, with 95% of patients in the Endolift-nanofat treated group demonstrating enhancement.
    CONCLUSIONS: Both methods notably enhance horizontal neck wrinkles; nevertheless, the combination of endolift laser and nanofat seems to be more efficient for treating horizontal neck wrinkles.
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  • DOI:
    文章类型: Journal Article
    UNASSIGNED: To describe cytologic findings from mandibular and superficial cervical lymph nodes in dogs with thyroid carcinoma and to determine prognostic factors associated with lymph node metastasis.
    UNASSIGNED: A total of 71 client-owned dogs with confirmed thyroid carcinoma that had cytologic results from at least 1 mandibular or superficial cervical lymph node between 2010 and 2020.
    UNASSIGNED: Medical records from 2 referral veterinary hospitals were retrospectively reviewed. Cytology of lymph nodes was reviewed for presence of metastasis by diplomates of the American College of Veterinary Pathologists. Thyroid tumor diameter and volume, tumor fixation, bilateral location, vascular invasion, and stage were recorded to determine effects on nodal metastasis.
    UNASSIGNED: A total of 154 lymph nodes (104 mandibular and 50 superficial cervical lymph nodes) from 71 dogs were cytologically evaluated, and 1/154 (0.6%) and 2/154 (1.3%) lymph nodes were noted to be definitively metastatic or probably metastatic, respectively. Given the infrequent rate of nodal metastasis (1.9% or less), statistical analysis of potential prognostic variables was not completed.
    UNASSIGNED: Routine lymph node cytology of mandibular and superficial cervical lymph nodes appeared to be of low yield when assessing for metastasis of canine thyroid carcinomas. The medial retropharyngeal and deep cervical lymph nodes should continue to be evaluated as they appeared to have higher metastatic rates, based on historic reports. Additional studies are needed to determine prognostic factors associated with lymph node metastasis and effects on patient survival.
    Résultats cytologiques dans les ganglions lymphatiques cervicaux mandibulaires et superficiels de chiens atteints d’un carcinome thyroïdien.
    UNASSIGNED: Décrire les résultats cytologiques obtenus des ganglions lymphatiques mandibulaires et cervicaux superficiels chez des chiens atteints d’un carcinome thyroïdien et déterminer les facteurs pronostiques associés aux métastases ganglionnaires.
    UNASSIGNED: Un total de 71 chiens appartenant à des clients atteints d’un carcinome thyroïdien confirmé avec des résultats cytologiques d’au moins un ganglion lymphatique cervical mandibulaire ou superficiel entre 2010 et 2020.
    UNASSIGNED: Les dossiers médicaux de 2 hôpitaux vétérinaires de référence ont été examinés rétrospectivement. La cytologie des ganglions lymphatiques a été examinée pour détecter la présence de métastases par des diplomates de l’American College of Veterinary Pathologists. Le diamètre et le volume de la tumeur thyroïdienne, la fixation de la tumeur, la localisation bilatérale, l’invasion vasculaire et le stade ont été notés pour déterminer les effets sur les métastases ganglionnaires.
    UNASSIGNED: Au total, 154 ganglions lymphatiques (104 ganglions lymphatiques mandibulaires et 50 ganglions lymphatiques cervicaux superficiels) provenant de 71 chiens ont été évalués par cytologie, et 1/154 (0,6 %) et 2/154 (1,3 %) ganglions lymphatiques ont été notés comme définitivement métastatiques ou probablement métastatiques, respectivement. Compte tenu du taux peu fréquent de métastases ganglionnaires (1,9 % ou moins), l’analyse statistique des variables pronostiques potentielles n’a pas été complétée.
    UNASSIGNED: La cytologie de routine des ganglions lymphatiques mandibulaires et cervicaux superficiels semblait être de faible rendement lors de l’évaluation des possibilités de métastases des carcinomes thyroïdiens canins. Les ganglions lymphatiques rétropharyngés médiaux et cervicaux profonds doivent continuer à être évalués car ils semblent présenter des taux métastatiques plus élevés, sur la base des rapports historiques. Des études supplémentaires sont nécessaires pour déterminer les facteurs pronostiques associés aux métastases ganglionnaires et les effets sur la survie des patients.(Traduit par Dr Serge Messier).
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  • 文章类型: Journal Article
    目的:评估Kushida形态计量模型(KMM)和氧去饱和指数(ODI)联合筛选阻塞性睡眠呼吸暂停个体的敏感性和特异性。
    方法:18岁以上成人的诊断试验研究,两性,多导睡眠图,身体质量指数,颈围和口内测量。
    结果:邀请了144名患者;其中,75符合排除标准。55例患者AHI≥5ev/h,14例患者AHI<5ev/h。评估了三个AHI截止点:AHI≥5,≥15,≥30ev/h。当采用截止点AHI≥5ev/h时,KMM显示灵敏度(SE)=60.0%,特异性(SP)=71.4%,曲线下面积的95%置信区间(AUC的95%CI)=0.655;KMM和ODI(KMM+ODI)的组合显示SE=73.0%,SP=71.4%(AUC的95%CI=0.779),ODI显示SE=76.4%和SP=92.9%(AUC的95%CI=0.815)。在截止点AHI≥15ev/h时,KMM呈现SE=64.1%,SP=76.7%(AUC的95%CI=0.735);KMMODI显示SE=82.1%,SP=83.3%(AUC的95%CI=0.895);ODI呈现SE=76.9%,SP=100.0%(AUC的95%CI=0.903)。对于AHI≥30ev/h的截止点,KMM显示SE=56.0%,SP=77.2%(AUC的95%CI=0.722);KMM+ODI显示SE=92.0%,SP=79.5%(AUC的95%CI=0.926);ODI显示SE=92.0%,SP=90.9%(AUC的95%CI=0.941)。
    结论:氧饱和度指数和Kushida形态测量模型的组合提高了该模型的敏感性和特异性,无论阻塞性睡眠呼吸暂停严重程度如何,这表明在风险预测方面具有更大的有效性。
    OBJECTIVE: To evaluate the sensitivity and specificity of the combined Kushida morphometric model (KMM) and the oxygen desaturation index (ODI) for screening individuals with obstructive sleep apnea.
    METHODS: Diagnostic test study with adults >18 years, both sexes, polysomnography, body mass index, neck circumference and intraoral measurements.
    RESULTS: 144 patients were invited; of these, 75 met the exclusion criteria. 55 individuals presented AHI ≥5 ev/h and 14, an AHI <5 ev/h. Three AHI cut-off points were evaluated: AHI ≥5, ≥15, ≥30 ev/h. When adopting the cut-off point of AHI ≥5 ev/h, the KMM showed sensitivity (SE) = 60.0 %, specificity (SP) = 71.4 % and 95 % confidence interval of the area under the curve (95 % CI of AUC) = 0.655; the combination of KMM and ODI (KMM + ODI) revealed SE = 73.0 %, SP = 71.4 % (95 % CI of AUC = 0.779) and the ODI showed SE = 76.4 % and SP = 92.9 % (95 % CI of AUC = 0.815). At the cut-off point of AHI ≥15 ev/h, the KMM presented SE = 64.1 %, SP = 76.7 % (95 % CI of AUC = 0.735); the KMM + ODI showed SE = 82.1 %, SP = 83.3 % (95 % CI of AUC = 0.895); and the ODI presented SE = 76.9 %, SP = 100.0 % (95 % CI of AUC = 0.903). For the cut-off point of AHI ≥30 ev/h, the KMM showed SE = 56.0 %, SP = 77.2 % (95 % CI of AUC = 0.722); the KMM + ODI revealed SE = 92.0 %, SP = 79.5 % (95 % CI of AUC = 0.926); and the ODI showed SE = 92.0 %, SP = 90.9 % (95 % CI of AUC = 0.941).
    CONCLUSIONS: The combination of oxygen desaturation index and Kushida morphometric model improved the sensitivity and specificity of this model regardless of obstructive sleep apnea severity suggesting greater effectiveness in risk prediction.
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