临床,描述了3例绵羊先天性脑积水(病例1、2和3)的脑电图和神经病理学特征。观察到的神经体征反映了端脑和脑干的损伤。在情况1和情况2中执行的脑电图显示出不同的模式:在情况1中是对称和同步的高压缓慢活动,在情况2中是低压缓慢活动。通过验尸,在所有的动物中,心室系统的扩张,尤其是侧脑室,观察到与扩张的心室周围的神经胶质反应有关。仅在病例3中,左桥小脑角的单外侧脑膜增厚似乎是阻塞性脑积水的原因。在其他两个大脑中(案例1和2),没有发现脑积水的潜在解剖原因,即使,在病例2中,由于大脑中度发育不全和存在非化脓性炎症,因此不排除代偿形式.这项工作的结果为绵羊脑积水病例的EEG表征做出了贡献;但是,对更多绵羊进行的进一步多学科研究可以更好地表征绵羊脑积水病例的EEG模式。
The clinical, electroencephalographic and neuro-pathological features of three cases (cases 1, 2 and 3) of congenital hydrocephalus in sheep were described. The observed neurological signs reflected damage in the telencephalon and brain stem. The electroencephalogram performed in case 1 and case 2 showed different patterns: symmetric and synchronous high-voltage slow-activity in case 1, and low-voltage slow-activity in case 2. By the post-mortem examination, in all the animals, dilatation of the ventricular system, especially of the lateral ventricles, associated with a glial reaction surrounding the dilated ventricles was observed. Only in case 3, a monolateral meningeal thickening at the left cerebellopontine angle seemed to be responsible for the obstructive hydrocephalus. In the other two brains (case 1 and 2), no potential anatomical cause for the hydrocephalus were detected, even if, in case 2, a compensatory form was not excluded due to the moderate hypoplasia of the cerebrum and the presence of the non-suppurative inflammation. The results of this work provide a contribution to the EEG characterisation in ovine hydrocephalus cases; nevertheless further multidisciplinary studies of a larger number of sheep could permit to better characterise the EEG pattern in ovine hydrocephalus cases.