背景:最近,流产的发生率逐渐增加,药物流产是终止妊娠的常用方法。在药物流产的过程中,阴道大量出血,导致紧急手术止血。急诊手术可能产生感染和器官损伤。我们的研究旨在调查药物流产期间大出血的高危因素。
方法:共有1062名接受药物流产的漏诊流产患者参加了这项回顾性研究。根据出血量,患者分为大出血组和对照组.通过比较两组的一般情况,比如生育史,子宫手术史,子宫肌瘤,等。,确定了药物流产期间大出血的高危因素.
结果:相对于对照组,大出血组先前进行过人工流产的患者比例较高(51.9%vs.38.1%,P=0.001)。此外,大出血组首次怀孕的女性比例较低(32.1%vs.40.4%),怀孕间隔较短的女性比例较高(44.9%vs.33.1%,P=0.03)。此外,两组在最大肌瘤大小方面有显著差异,闭经的持续时间,孕周(P<0.05)。
结论:在这项研究中,我们确定,人工流产史和闭经时间>11周是药物流产期间阴道大量出血的高危因素.
BACKGROUND: Recently, the incidence of missed miscarriage has gradually increased, and medical abortion is a common method to terminate a pregnancy. In the process of medical abortion, massive vaginal bleeding takes place, leading to emergency surgical haemostasis. Emergency surgery may produce infection and organ damage. Our study aimed to investigate the high-risk factors for massive haemorrhage during a medical abortion.
METHODS: A total of 1062 missed miscarriage patients who underwent medical abortion participated in this retrospective study. According to the amount of bleeding, the patients were divided into a massive haemorrhage group and a control group. By comparing the general conditions of the two groups, such as fertility history, uterine surgery history, uterine fibroids, etc., the high-risk factors for massive haemorrhage during medical abortion were identified.
RESULTS: Relative to the control group, the massive haemorrhage group exhibited a higher proportion of patients with a previous artificial abortion (51.9% vs. 38.1%, P = 0.001). Additionally, the massive haemorrhage group had a lower percentage of first-time pregnant women (32.1% vs. 40.4%) and a higher proportion of women with shorter pregnancy intervals (44.9% vs. 33.1%, P = 0.03). Furthermore, there were notable differences between the two groups regarding maximum fibroid size, the duration of amenorrhea, and gestational week (P < 0.05).
CONCLUSIONS: In this study, we determined that a history of artificial abortion and an amenorrhea duration of > 11 weeks represented high-risk factors for massive vaginal bleeding during medical abortion in missed miscarriage patients.