犬媒介传播疾病(CVBD)是由节肢动物媒介传播的多种病原体引起的一组传染病。临床症状通常包括发热等症状,厌食症,减肥,血液疾病,肝脾肿大,以及其他可能导致合并症狗死亡的人。一些导致CVBD的病原体由于其人畜共患传播而对人类健康构成严重威胁。本研究旨在确定人畜共患媒介传播疾病的患病率(立克次体立克次体,吞噬体,犬埃里希亚,汉塞巴尔通体,和婴儿利什曼原虫)在有或没有这些病原体的临床症状的国内撒丁岛犬中。从142只狗收集血清样品并通过血清学分析进行检查。还评估了提示这些病原体的临床体征。得到的结果表明,33(33/140;23.6%),22(22/134;16.4%),14(14/142;9.9%),20(20/66;30.3%),26只(26/108;24.1%)狗的立克次体血清呈阳性。,无菌血症。,埃里希亚sp.,巴尔通菌sp.,和利什曼尼亚。抗体,分别。在这些狗当中,12只狗至少有一个临床症状(8.5%),18例(12.7%)同时出现两种以上症状。此外,在无症状的狗中(93/142;65.5%),13%(n=12)的吞噬细胞菌检测呈阳性,12%(n=11)检测为阳性。9%(n=8)的犬大肠杆菌检测呈阳性,12%(n=11)的婴儿乳杆菌检测呈阳性,19%(n=18)的立克次生菌检测呈阳性。这项调查代表了第一项评估北撒丁岛犬中不同犬媒介传播病原体的研究。由于这里检测到的病原体代表了新出现的人畜共患疾病,这些结果突出表明,需要进行进一步研究,以增加对撒丁岛这些报道不足的媒介传播病原体的认识.
Canine vector-borne diseases (CVBDs) comprise a group of infectious diseases caused by a wide range of pathogens transmitted by arthropod vectors. Clinical signs commonly involve symptoms such as fever, anorexia, weight loss, blood disorders, hepatosplenomegaly, and others that can lead to death in dogs with comorbidities. Some pathogens responsible for CVBDs constitute a serious threat to human health due to their zoonotic transmission. This study aimed to determine the prevalence of zoonotic vector-borne diseases (Rickettsia rickettsii, Anaplasma phagocytophilum, Ehrlichia canis, Bartonella henselae, and Leishmania infantum) in domestic Sardinian dogs with and without clinical signs of these pathogens. Blood serum samples were collected from 142 dogs and examined through serological analysis. Clinical signs suggestive of these pathogens were also evaluated. The results obtained showed that 33 (33/140; 23.6%), 22 (22/134; 16.4%), 14 (14/142; 9.9%), 20 (20/66; 30.3%), and 26 (26/108; 24.1%) dogs were seropositive for Rickettsia sp., Anaplasma sp., Ehrlichia sp., Bartonella sp., and Leishmania sp. antibodies, respectively. Among these dogs, 12 dogs presented with at least one clinical sign (8.5%), while 18 (12.7%) showed more than two symptoms at the same time. Furthermore, among the asymptomatic dogs (93/142; 65.5%), 13% (n = 12) tested positive for A. phagocytophilum, 12% (n = 11) tested positive for B. henselae, 9% (n = 8) tested positive for E. canis, 12% (n = 11) tested positive for L. infantum, and 19% (n = 18) tested positive for R. rickettsii. This survey represents the first study assessing different canine vector-borne pathogens in dogs from North Sardinia. Since the pathogens detected here represent emerging zoonotic diseases, these results highlight the need to undertake further studies to increase the knowledge of these under-reported vector-borne pathogens in Sardinia.