Reconstructive surgery

重建手术
  • 文章类型: Journal Article
    目的:灌注不足是乳房切除术后乳房再造术组织转移中部分皮瓣丢失的最常见原因。当前最先进的技术使用计算机断层扫描血管造影(CTA)来定位最佳的穿孔器。不幸的是,这些技术既昂贵又耗时,而且在手术过程中无法执行.动态红外热成像(DIRT)可以为这些缺点提供解决方案。
    方法:该研究提出了将DIEP皮瓣乳房重建过程中的热成像检查与使用卷积神经网络的自动分割方法相结合。传统的分割技术和外科医生的注释用于创建用于训练的自动标签。
    结果:用于图像注释的网络能够在最少的硬件上实时标记,并且创建的标签可用于定位和量化穿孔器候选,以在2分钟后获得0.8的骰子得分准确度,在4分钟后获得0.9的骰子得分准确度。
    结论:这些结果允许一种计算系统,该系统可以在手术期间就地使用,以提高手术成功率。跟踪和测量穿孔器及其灌注面积的能力允许较少的主观结果,并帮助外科医生为DIEP皮瓣乳房重建选择最合适的穿孔器。
    OBJECTIVE: Inadequate perfusion is the most common cause of partial flap loss in tissue transfer for post-mastectomy breast reconstruction. The current state-of-the-art uses computed tomography angiography (CTA) to locate the best perforators. Unfortunately, these techniques are expensive and time-consuming and not performed during surgery. Dynamic infrared thermography (DIRT) can offer a solution for these disadvantages.
    METHODS: The research presented couples thermographic examination during DIEP flap breast reconstruction with automatic segmentation approach using a convolutional neural network. Traditional segmentation techniques and annotations by surgeons are used to create automatic labels for the training.
    RESULTS: The network used for image annotation is able to label in real-time on minimal hardware and the labels created can be used to locate and quantify perforator candidates for selection with a dice score accuracy of 0.8 after 2 min and 0.9 after 4 min.
    CONCLUSIONS: These results allow for a computational system that can be used in place during surgery to improve surgical success. The ability to track and measure perforators and their perfused area allows for less subjective results and helps the surgeon to select the most suitable perforator for DIEP flap breast reconstruction.
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  • 文章类型: Case Reports
    本文报道了面动脉(FA)的一种罕见解剖变体-即,双FA模式-在广泛的外科和美学医学学科中具有重要意义。
    该研究涉及FA及其变体的病例报告和文献综述。这种情况是61岁的女性尸体,在解剖解剖过程中发现了单侧FA变异分支模式。
    解剖显示,上颌动脉两侧的两个独立分支对典型FA分布的异常供应。第一个分支,称为FA1,遵循一个典型的FA过程,从外颈动脉通过舌侧供应面部的下部,下唇,和精神动脉分支。第二个分支,称为FA2,出现在典型的面横动脉起源附近的上颌动脉上方,通过上唇供应面部的上部,鼻侧,和有角的动脉分支。通过解剖未观察到两个分支之间的直接联系。观察到的分支模式以前没有在文献中报道过,并且对手术计划和干预具有重要意义。
    这项研究强调了在需要对面部动脉供应的精确解剖学知识的程序中理解变体FA解剖结构的重要性。重复和/或次级面部动脉需要仔细考虑它们对头颈部手术成功的潜在影响。真皮填充剂,和鼻出血栓塞术。
    UNASSIGNED: This paper reports a rare anatomical variant of the facial artery (FA) - namely, a double FA pattern - which has significant implications in a wide range of surgical and aesthetic medicine disciplines.
    UNASSIGNED: The study involves a case report and literature review of the FA and its variants. The case is that of a 61-year-old female cadaver with a unilateral FA variant branching pattern discovered during a cadaveric dissection for an anatomy course.
    UNASSIGNED: The dissection revealed an unusual supply of the typical FA distribution by two separate branches from either side of the maxillary artery. The first branch, termed FA1, followed a typical FA course arising from the external carotid to supply the lower portion of the face via lingual, inferior labial, and mental arterial branches. The second branch, termed FA2, arose superior to the maxillary artery near the origin of a typical transverse facial artery, to supply the upper portion of the face via superior labial, lateral nasal, and angular arterial branches. No direct communication between the two branches was observed grossly via dissection. The observed branching pattern has not previously been reported in literature and has critical implications for surgical planning and intervention.
    UNASSIGNED: This study emphasizes the importance of understanding variant FA anatomy in procedures requiring precise anatomical knowledge of arterial supply to the face. Duplicate and/or secondary facial arteries necessitate careful consideration for their potential consequences on the success of surgery of the head and neck, dermal fillers, and embolization for epistaxis procedures.
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  • 文章类型: Case Reports
    该病例显示了一名57岁的男性在右侧腹区患有脂肪肉瘤。该病例的手术治疗包括广泛局部切除术(WLE),使用肋间后动脉螺旋桨皮瓣重建后采取。术后护理包括定期检查重复的迹象。与类似病例的比较突出了脂肪肉瘤的临床引入和手术方法的可变性。这个案例强调了方便诊断的意义,严格的外科手术,以及在监督脂肪肉瘤方面的成功重建。本病例报告强调了临床用药,外科手术调解,和术后护理包括治疗巨大脂肪肉瘤,并将此病例与类似病例进行比较,以强调治疗脂肪肉瘤的挑战和程序。
    This case shows the administration of a 57-year-old male with liposarcoma within the right flank region. Surgical treatment of the case included wide local excision (WLE), taken after reconstruction utilizing a posterior intercostal artery propeller flap. Postoperative care included regular checking for signs of repeat. Comparison with similar cases highlights the changeability in clinical introduction and surgical approaches for liposarcomas. This case emphasizes the significance of convenient diagnosis, fastidious surgical procedures, and successful reconstruction in overseeing liposarcomas. This case report points to highlights the clinical administration, surgical intercession, and postoperative care included in treating a giant liposarcoma and compares this case with similar instances to emphasize the challenges and procedures in treating liposarcomas.
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  • 文章类型: Systematic Review
    背景:机器人辅助手术(RAS)在许多外科专业领域取得了重大进展,尽管机器人在整形和重建手术中的应用仍有待广泛建立。本系统评价旨在评估RAS在整形和重建手术中的作用。
    方法:审查方案已发布,并事先注册为CRD42024507420。在MEDLINE进行了相关研究的全面电子搜索,Embase和谷歌学者数据库。
    结果:总体而言,最初确定了132项研究,其中,44项研究满足资格标准,累计239例患者。RAS在微血管手术中显示出高度的手术成功和吻合通畅性。机器人和手动程序之间的围手术期不良事件没有显着差异。
    结论:RAS可以在整形和重建手术中实施,具有良好的疗效和安全性,特别是显微外科吻合和经口手术。
    BACKGROUND: Robotic assisted surgery (RAS) has seen significant advancement in many surgical specialties, although the application of robotics in plastic and reconstructive surgery remains to be widely established. This systematic review aims to assess the role of RAS in plastic and reconstructive surgery.
    METHODS: The review protocol was published and registered a priori as CRD42024507420. A comprehensive electronic search for relevant studies was performed in MEDLINE, Embase and Google scholar databases.
    RESULTS: Overall, 132 studies were initially identified, of which, 44 studies satisfied the eligibility criteria with a cumulative total of 239 patients. RAS demonstrated a high degree of procedural success and anastomotic patency in microvascular procedures. There was no significant difference in periprocedural adverse events between robotic and manual procedures.
    CONCLUSIONS: RAS can be feasibly implemented in plastic and reconstructive surgery with a good efficacy and safety profile, particularly for microsurgical anastomosis and trans-oral surgery.
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  • 文章类型: Journal Article
    3D生物打印领域在再生医学领域迅速兴起,在处理器官短缺问题方面提供了巨大的潜力。尽管处于早期阶段,它有可能准确地复制组织结构,为重建手术提供新的潜在解决方案。这篇综述探讨了3D生物打印在再生医学中的各种应用。制药,和食品工业,特别关注耳朵,皮肤,和骨组织,因为它们在该领域的独特挑战和影响。耳重建中软骨和骨支架的制造取得了重大进展,然而,在功能成熟的挑战仍然存在。最近的进步凸显了患者专用耳朵替代品的潜力,强调需要进行广泛的临床试验。在皮肤再生中,3D生物打印解决了现有模型中的限制,提供改善伤口愈合和现实皮肤模型的机会。虽然存在挑战,生物材料和原位生物打印的进展充满希望。在骨骼再生中,3D生物打印为缺陷提供个性化解决方案,但支架设计的完善和解决监管和伦理方面的考虑是至关重要的。3D生物打印在医学领域的变革潜力有望重新定义治疗方法并提供个性化治疗和功能组织。跨学科合作对于充分实现3D生物打印功能至关重要。这篇综述详细分析了当前的方法,挑战,以及耳朵3D生物打印的前景,皮肤,和骨组织再生。
    The field of 3D bioprinting is rapidly emerging within the realm of regenerative medicine, offering significant potential in dealing with the issue of organ shortages. Despite being in its early stages, it has the potential to replicate tissue structures accurately, providing new potential solutions for reconstructive surgery. This review explores the diverse applications of 3D bioprinting in regenerative medicine, pharmaceuticals, and the food industry, specifically focusing on ear, skin, and bone tissues due to their unique challenges and implications in the field. Significant progress has been made in cartilage and bone scaffold fabrication in ear reconstruction, yet challenges in functional maturation persist. Recent advancements highlight the potential for patient-specific ear substitutes, emphasizing the need for extensive clinical trials. In skin regeneration, 3D bioprinting addresses limitations in existing models, offering opportunities for improved wound healing and realistic skin models. While challenges exist, progress in biomaterials and in-situ bioprinting holds promise. In bone regeneration, 3D bioprinting presents personalized solutions for defects, but scaffold design refinement and addressing regulatory and ethical considerations are crucial. The transformative potential of 3D bioprinting in the field of medicine holds the promise of redefining therapeutic approaches and delivering personalized treatments and functional tissues. Interdisciplinary collaboration is essential for fully realizing the capabilities of 3D bioprinting. This review provides a detailed analysis of current methodologies, challenges, and prospects in 3D bioprinting for ear, skin, and bone tissue regeneration.
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  • 文章类型: Journal Article
    目前在临床实践中尚未实施机器灌注器官或转位自体组织的连续氧合监测。氧合是可用于验证组织活力和指导矫正干预的关键参数。如灌注机参数或手术翻修。这项工作提出了一种基于氧敏感的创新技术,磷光金属卟啉允许对离体灌注的血管化筋膜皮瓣进行连续和非侵入性的氧气监测。该方法包括一个小的,低能量光学经皮氧传感器应用于皮瓣的皮肤桨以及放置在管道中的氧传感装置。设计间歇性灌注设置以研究该技术在总共54个灌注循环中的响应时间和准确性。我们进一步评估了连续氧测量值与金标准灌注活力指标(如血管阻力)之间的相关性。具有很好的一致性,表明有可能以高频率监测移植物的活力,开辟了未来采用反馈控制算法的可能性。这项概念验证研究在灌注机快速临床采用时,在重建手术和移植中开辟了一系列研究和临床应用,有可能改善各种外科手术的结果,并显着增加获得移植药物的机会。
    Continuous oxygenation monitoring of machine-perfused organs or transposed autologous tissue is not currently implemented in clinical practice. Oxygenation is a critical parameter that could be used to verify tissue viability and guide corrective interventions, such as perfusion machine parameters or surgical revision. This work presents an innovative technology based on oxygen-sensitive, phosphorescent metalloporphyrin allowing continuous and non-invasive oxygen monitoring of ex-vivo perfused vascularized fasciocutaneous flaps. The method comprises a small, low-energy optical transcutaneous oxygen sensor applied on the flap\'s skin paddle as well as oxygen sensing devices placed into the tubing. An intermittent perfusion setting was designed to study the response time and accuracy of this technology over a total of 54 perfusion cycles. We further evaluated correlation between the continuous oxygen measurements and gold-standard perfusion viability metrics such as vascular resistance, with good agreement suggesting potential to monitor graft viability at high frequency, opening the possibility to employ feedback control algorithms in the future. This proof-of-concept study opens a range of research and clinical applications in reconstructive surgery and transplantation at a time when perfusion machines undergo rapid clinical adoption with potential to improve outcomes across a variety of surgical procedures and dramatically increase access to transplant medicine.
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  • 文章类型: Case Reports
    这项工作得到了海军医科大学和上海理工大学联合项目(2020-RZ04)的支持,上海长征医院创新临床研究项目(2020YLCYJ-Y16),海军医科大学学术项目(2022QN073)。作者没有利益冲突要声明。
    UNASSIGNED: This work was supported by the Naval Medical University and the University of Shanghai for Science and Technology Joint Projects (2020-RZ04), the Innovative Clinical Research Program of Shanghai Changzheng Hospital (2020YLCYJ-Y16), and the academic project of Naval Medical University (2022QN073). The authors have no conflicts of interest to declare.
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  • 文章类型: Journal Article
    烧伤重建结果是一个越来越多的调查领域。尽管有证据表明激光治疗后疤痕特征的物理改善,关于患者报告结果的信息很少.这项研究的目的是比较有和没有激光治疗的烧伤幸存者的患者报告结果。该研究包括烧伤模型系统国家数据库中一个中心的参与者;将接受烧伤疤痕门诊激光治疗的参与者与未接受激光治疗的烧伤幸存者进行比较。检查了以下结果:对生活量表的满意度,退伍军人兰德调查的心理和身体成分摘要,和PROMIS疼痛强度量表。回归分析在12个月和24个月时检查了激光治疗与每个结果之间的关联。研究人群包括287名成年烧伤幸存者(65名激光组,222对照组)。两组之间的显着差异包括:烧伤大小(激光:14.9,13.5SD,对照:8.9,11.1SD;p<0.001),保险类型(p=0.036),吸入性损伤(激光:17.2%,对照:2.7%;p<0.001),和呼吸机要求(激光:27.7%,控制:13.5%;p=0.013)。在两个随访时间点,激光治疗与任何结果无关。需要进一步的研究来开发患者报告的结果指标,这些指标对接受激光治疗的烧伤幸存者所经历的临床变化更敏感。
    Burn reconstruction outcomes are an area of growing investigation. Although there is evidence of measured physical improvements in scar characteristics after laser treatment, there is little information on patient reported outcomes. The purpose of this study is to compare patient reported outcomes between burn survivors with and without laser treatment. The study included participants in the Burn Model Systems National Database at a single center; participants that received outpatient laser treatment for burn scars were compared to a matched group of burn survivors that did not receive laser. The following outcomes were examined: Satisfaction With Life Scale, Mental and Physical Component Summary of the Veterans Rand Survey, and the PROMIS Pain Intensity Scale. Regression analyses examined the associations between laser treatment and each outcome at 12 and 24 months. The study population included 287 adult burn survivors (65 laser group, 222 control group). The significant differences found between the two groups included: burn size (laser: 14.9, 13.5 SD, control: 8.9, 11.1 SD; p<0.001), insurance type (p=0.036), inhalation injury (laser: 17.2%, control: 2.7%; p<0.001), and ventilator requirement (laser: 27.7%, control: 13.5%; p=0.013). Laser treatment was not associated with any of the outcomes at both follow-up time points. Further research is needed to develop patient reported outcome measures that are more sensitive to the clinical changes experienced by burn survivors receiving laser treatment.
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  • 文章类型: Journal Article
    目的:患有Kienbock病的患者可表现为冠状骨折和月骨近端塌陷(统一B2/Bain1级,2B级)。传统上,这被认为是无法挽救的。然而,股骨内侧滑车(MFT)骨软骨重建,用来重建月近表面,可以与冠状平面骨折的复位和修复配对,从而恢复了腕骨中部。这项研究的目的是报告MFT骨软骨重建时的月冠状骨折固定后的影像学和临床结果。
    方法:这是一项在单一机构进行的回顾性研究。我们确定了2014年至2023年接受MFT骨软骨重建的Kienbock病患者。如果患者在手术时固定了月球远端关节面的冠状骨折,则将其包括在内。评估影像学和临床参数,包括腕骨高度比,联合汇率,异位骨化的存在,需要翻修手术,和患者报告的结果指标。
    结果:包括33例患者,平均年龄27.5岁(范围:15-41);19(58%)是女性。平均影像学随访时间为5.8个月,平均临床随访时间为22.6个月。在30/33例患者中实现了联合(91%)。腕骨高度比从1.32提高到1.4。两名患者(6%)需要再次手术,一种用于去除异位骨化,另一种用于转换为近排腕骨切除术。患者在简短的密歇根手问卷和患者报告的结果测量信息上肢评分中表现出有意义的改善。手术前后的活动范围相似。
    结论:MFT骨软骨重建的Lunate冠状骨折固定术代表了Kienbock病患者的另一种治疗选择。该技术可在月肉重建期间恢复腕中关节,并可使患者避免抢救程序。早期影像学和临床结果是有希望的。
    方法:治疗IV。
    OBJECTIVE: Patients with Kienbock disease can present with coronal fracture and collapse of the proximal lunate (Unified B2/Bain grade 1, 2B). Traditionally, this was considered unsalvageable. However, medial femoral trochlea (MFT) osteochondral reconstruction, used to recreate the proximal lunate surface, can be paired with reduction and repair of the coronal plane fracture, thus restoring midcarpal congruity. The purpose of this study was to report radiographic and clinical outcomes following lunate coronal fracture fixation at the time of MFT osteochondral reconstruction.
    METHODS: This was a retrospective study performed at a single institution. We identified patients with Kienbock disease who underwent MFT osteochondral reconstruction from 2014 to 2023. Patients were included if they had a coronal fracture of the lunate distal articular surface fixed at the time of surgery. Radiographic and clinical parameters were evaluated, including carpal height ratio, union rate, presence of heterotopic ossification, need for revision surgery, and patient-reported outcome measures.
    RESULTS: Thirty-three patients were included, with a mean age of 27.5 years (range: 15-41); 19 (58%) were women. Mean radiographic follow-up time was 5.8 months, and mean clinical follow-up time was 22.6 months. Union was achieved in 30/33 patients (91%). Carpal height ratio improved from 1.32 to 1.4. Two patients (6%) required reoperation, one for removal of heterotopic ossification and another for conversion to proximal row carpectomy. Patients demonstrated meaningful improvement in brief Michigan Hand Questionnaire and Patient-Reported Outcomes Measurement Information Upper Extremity scores. Range of motion before and after surgery was similar.
    CONCLUSIONS: Lunate coronal fracture fixation with MFT osteochondral reconstruction represents an additional management option in select patients with Kienbock disease. This technique restores the midcarpal joint during lunate reconstruction and may allow patients to avoid salvage procedures. Early radiographic and clinical outcomes are promising.
    METHODS: Therapeutic IV.
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  • 文章类型: Journal Article
    背景和目标:大型语言模型(LLM)正在成为整形外科中的有价值的工具,有可能降低外科医生的认知负荷并改善患者的预后。本研究旨在评估和比较两种最常见和最容易获得的LLM的当前状态,打开AI的ChatGPT-4和Google的GeminiPro(1.0Pro),在整形和重建外科手术中提供术中决策支持。材料和方法:我们为每个LLM提供了跨越5个程序的32个独立的术中场景。我们使用5分和3分的李克特量表进行医疗准确性和相关性,分别。我们使用Flesch-Kincaid等级(FKGL)和Flesch阅读轻松(FRE)评分确定了响应的可读性。此外,我们测量了模型的响应时间。我们使用曼-惠特尼U检验和学生t检验比较了性能。结果:ChatGPT-4在提供准确(3.59±0.84vs.3.13±0.83,p值=0.022)和相关(2.28±0.77vs.1.88±0.83,p值=0.032)响应。或者,双子座提供了更简洁易读的回答,平均FKGL(12.80±1.56)显著低于ChatGPT-4(15.00±1.89)(p<0.0001)。然而,FRE评分无差异(p=0.174).此外,双子座的平均反应时间(8.15±1.42s)明显快于ChatGPT-4(13.70±2.87s)(p<0.0001)。结论:尽管ChatGPT-4提供了更准确和相关的响应,两种模型均显示出作为术中工具的潜力.然而,它们在不同手术中的表现不一致,强调需要进一步的培训和优化,以确保它们作为术中决策支持工具的可靠性.
    Background and Objectives: Large language models (LLMs) are emerging as valuable tools in plastic surgery, potentially reducing surgeons\' cognitive loads and improving patients\' outcomes. This study aimed to assess and compare the current state of the two most common and readily available LLMs, Open AI\'s ChatGPT-4 and Google\'s Gemini Pro (1.0 Pro), in providing intraoperative decision support in plastic and reconstructive surgery procedures. Materials and Methods: We presented each LLM with 32 independent intraoperative scenarios spanning 5 procedures. We utilized a 5-point and a 3-point Likert scale for medical accuracy and relevance, respectively. We determined the readability of the responses using the Flesch-Kincaid Grade Level (FKGL) and Flesch Reading Ease (FRE) score. Additionally, we measured the models\' response time. We compared the performance using the Mann-Whitney U test and Student\'s t-test. Results: ChatGPT-4 significantly outperformed Gemini in providing accurate (3.59 ± 0.84 vs. 3.13 ± 0.83, p-value = 0.022) and relevant (2.28 ± 0.77 vs. 1.88 ± 0.83, p-value = 0.032) responses. Alternatively, Gemini provided more concise and readable responses, with an average FKGL (12.80 ± 1.56) significantly lower than ChatGPT-4\'s (15.00 ± 1.89) (p < 0.0001). However, there was no difference in the FRE scores (p = 0.174). Moreover, Gemini\'s average response time was significantly faster (8.15 ± 1.42 s) than ChatGPT\'-4\'s (13.70 ± 2.87 s) (p < 0.0001). Conclusions: Although ChatGPT-4 provided more accurate and relevant responses, both models demonstrated potential as intraoperative tools. Nevertheless, their performance inconsistency across the different procedures underscores the need for further training and optimization to ensure their reliability as intraoperative decision-support tools.
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