Mediastinal Cyst

纵隔囊肿
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    文章类型: Case Reports
    A pericardial cyst is a rare and benign lesion, most commonly of congenital origin. A female patient of 35 years old was admitted to the emergency department of our institution, for non-irradiating thoracic pain associated with a dyspnea. A CT-Scan was performed, and a pericardial cyst of a large size was found. A surgical procedure through thoracoscopy was performed to enhance the symptomatology of the patient and to eradicate the cyst. The diagnosis of these lesions is most commonly sporadic after a radiography performed for other causes. Most of the time these lesions are asymptomatic (although thoracic pains, chronic cough and dyspnea amongst others may be observed). In case of suspicion (related to radiography or an eventual symptomatology) a thoracic scan is performed with a contrasting product for the confirmation and localization of the cyst. In addition to the diagnosis and the localization, it is best to perform a transthoracic ultrasound which enables a differential diagnosis with other lesions (lipoma, aortic aneurysm, solid tumour, and a left ventricle aneurysm etc.). A surgical treatment is recommended in symptomatic cases. In non-symptomatic cases, a transthoracic ultrasound is recommended.
    Le kyste péricardique est une lésion rare, bénigne et le plus souvent congénitale. Nous rapportons le cas d’une patiente de 35 ans admise aux urgences de notre institution dans le cadre d’une douleur thoracique associée à une dyspnée. La réalisation d’un scanner thoracique permet de mettre en évidence un kyste péricardique d’une grande taille. Une intervention par chirurgie thoracoscopique vidéo-assistée a été réalisée afin de mettre à plat le kyste et, ainsi, d’améliorer la symptomatologie de la patiente. Le diagnostic de ces lésions est le plus souvent fait de manière fortuite, sur une radiographie réalisée pour une autre raison. Il s’agit généralement de lésions asymptomatiques bien que des douleurs thoraciques, une toux chronique ou encore une dyspnée sont retrouvées dans certains cas. En cas de suspicion, un scanner thoracique avec produit de contraste permet de confirmer et localiser précisément la lésion. Une échographie trans-thoracique permet, en plus, de réaliser un diagnostic différentiel avec d’autres lésions (lipome, anévrysme aortique, tumeur solide, anévrysme du ventricule gauche, etc…). En cas de lésion symptomatique, une prise en charge chirurgicale est recommandée. Dans les cas asymptomatiques, un suivi par échographie trans-thoracique est recommandé.
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  • 文章类型: Case Reports
    纵隔甲状旁腺囊肿(MPCs)极为罕见,由甲状旁腺引起并位于胸腔内的良性病变。本研究旨在增进对MPC的理解,强调这种罕见疾病的准确诊断和管理方法。一名46岁女性出现吞咽困难一周。血液检查显示甲状旁腺激素(PTH)升高(112.8pg/mL)和血清钙正常(9.54mg/dL)。超声检查发现,明确的囊性结节,大小为46×30×25毫米,在胸部右上三分之一向胸骨后延伸。随后的胸部高分辨率计算机断层扫描扫描显示上纵隔有大的占位病变(47×43×31mm),在食道附近,提示食管重复囊肿或,不太可能,支气管囊肿.进行了电视辅助胸腔镜手术(VATS),整个囊肿被切除,组织学证实为纵隔甲状旁腺囊肿。由于PC的稀有性和多样化的临床表现,纵隔受累提出了诊断挑战。有症状的病例需要手术切除,随着VATS成为一种有利的方法。
    Mediastinal parathyroid cysts (MPCs) are extremely rare, benign lesions arising from the parathyroid glands and residing within the thoracic cavity. This study aims to advance understanding of MPC, emphasizing accurate diagnosis and management approaches for this rare condition. A 46-year-old woman presented with dysphagia for one week. Blood tests revealed elevated parathyroid hormone (PTH) (112.8 pg/mL) and normal serum calcium (9.54 mg/dL). Ultrasonography identified a large, well-defined cystic nodule measuring 46 × 30 × 25 mm, extending retro-sternally in the right upper third of the chest. A subsequent high-resolution computed tomography scan of the chest revealed a large space-occupying lesion (47 × 43 × 31 mm) in the superior mediastinum, near the esophagus, suggesting an esophageal duplication cyst or, less likely, a bronchogenic cyst. Video-assisted thoracoscopic surgery (VATS) was performed, and the entire cyst was excised, confirmed histologically as a mediastinal parathyroid cyst. Mediastinal involvement of PCs poses diagnostic challenges due to their rarity and diverse clinical presentations. Surgical excision is necessary for symptomatic cases, with VATS emerging as a favorable approach.
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  • 文章类型: Case Reports
    背景:原发性心脏肿瘤,虽然罕见,由于其不同的病理和表现,目前显著的临床挑战。肺癌经常转移到心脏;然而,在文献中,涉及不同来源的原发性心脏肿瘤以及原发性肺癌的病例极为罕见。
    方法:我们报告了一例53岁的女性咯血,随后被诊断为左心房粘液瘤,肺鳞状细胞癌,还有胸腺囊肿.单个患者中多种非同源肿瘤的共存极为罕见。
    结论:该病例强调了诊断和治疗多个不同肿瘤患者的复杂性。原发性心脏粘液瘤的同时发生,肺鳞状细胞癌,胸腺囊肿是前所未有的,为未来的临床实践提供有价值的见解。
    BACKGROUND: Primary cardiac tumors, while rare, present significant clinical challenges due to their diverse pathology and presentation. Lung cancer frequently metastasizes to the heart; however, cases involving primary cardiac tumors of different origins alongside primary lung cancer are exceedingly rare in the literature.
    METHODS: We report the case of a 53-year-old female who presented with hemoptysis and was subsequently diagnosed with a left atrial myxoma, pulmonary squamous cell carcinoma, and a thymic cyst. This coexistence of multiple non-homologous tumors in a single patient is exceedingly rare.
    CONCLUSIONS: This case underscores the complexity of diagnosing and managing patients with multiple distinct tumors. The simultaneous occurrence of a primary cardiac myxoma, pulmonary squamous cell carcinoma, and thymic cyst is unprecedented, providing valuable insights for future clinical practice.
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  • 文章类型: Journal Article
    介绍心包囊肿(PC)很少见,非恶性,和先天性异常。PC的识别和治疗仍然是一个重大挑战,对手术管理的研究有限。方法回顾性分析2002年2月至2022年12月在新疆医科大学第一附属医院接受手术治疗的PC患者。结果在研究期间,共有55例患者因PC而接受了手术治疗。31名女性,24名男性。患者的平均年龄为44.7±12.9(6至63岁)。在50例(90.9%)患者中,PC位于右半胸,在5例(9.1%)患者中,PC位于左半胸。方法采用电视胸腔镜手术(VATS)43例(78.2%),开胸手术11例(20%),1例(1.8%)胸骨正中切开术。术后平均住院时间为5.6天(2至14天)。3例患者出现术后并发症(2例胸腔积液,一种肺炎),而没有观察到任何患者因手术而死亡。41例(74.5%)患者术后随访3个月至8年,在此期间没有发现复发性囊肿。结论在这项单中心回顾性研究中,根据囊肿的特点,我们证明了心包囊肿的治疗是一种合适的手术。VATS已被证明对患有PC的患者非常有效和安全,提供有效降低术后发病率的优势。
    Introduction Pericardial cysts (PCs) are infrequent, non-malignant, and congenital abnormalities. The identification and treatment of PCs remain a significant challenge, with limited research on surgical management. Methods We performed a retrospective study of patients with PCs who underwent surgical intervention at the First Affiliated Hospital of Xinjiang Medical University from February 2002 to December 2022. Results A total of 55 patients underwent surgery due to PCs during the study period. Thirty-one were females and 24 were males. The average age of the patients was 44.7 ± 12.9 (six to 63 years old). PCs were located in the right hemithorax in 50 (90.9%) patients and left hemithorax in five (9.1%) patients. Approach methods were video-assisted thoracoscopic surgery (VATS) in 43 (78.2%) cases; thoracotomy in 11 (20%) cases, and median sternotomy in one (1.8%) cases. The average postoperative hospitalization period was 5.6 days (two to 14 days). Three patients developed postoperative complications (two pleural effusion, one pneumonia), whereas no mortality was observed in any patient due to the operation. Forty-one patients (74.5%) were followed up for three months to eight years postoperatively, during which no recurrent cysts were detected. Conclusion In this single-center retrospective study, we demonstrated that pericardial cyst cure is an appropriate operation according to cyst characteristics. VATS has been shown to be highly effective and safe in patients with PCs, offering the advantage of reducing postoperative morbidity efficiently.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    颈部肿块常见于儿童。鉴别诊断包括传染性,先天性和肿瘤性病变。我们报告了一例罕见的胸腺颈部肿块的男孩,在他的童年中期,有左前外侧颈部肿块的病史,与发烧无关。吞咽困难或呼吸急促。放射学评估显示有一张胸腺咽管囊肿的照片。胸腺残留和胸腺咽管囊肿是由闭塞失败引起的,在儿童中可能表现为颈外侧肿块。最有效的治疗方法是全手术切除。这种特殊情况凸显了临床医生在评估患有颈部肿块的儿科患者时,对广泛的鉴别诊断有高度怀疑的重要性。此外,我们强调始终将咽部囊肿作为鉴别诊断的重要性.
    Neck masses are frequently seen in children. The differential diagnosis includes infectious, congenital and neoplastic lesions. We report a case of rare thymic neck mass in a boy in his middle childhood presented with a history of a left anterolateral neck mass not associated with fever, dysphagia or shortness of breath. The radiographic evaluation showed a picture of a thymopharyngeal duct cyst. Thymic remnant and thymopharyngeal duct cyst are caused by the failure of obliteration and might appear as a lateral neck mass in children. The most effective treatment for a thymopharyngeal duct cyst is total surgical excision. This particular case highlights the importance for clinicians to have a high index of suspicion for a broad differential diagnosis when evaluating paediatric patients who present with neck mass. Additionally, we emphasise the importance of consistently considering thymopharyngeal cyst as differential diagnosis.
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  • 文章类型: Case Reports
    该病例报告详细介绍了一种罕见的胸腺基底细胞样癌,最初被误解为纵隔畸胎瘤,强调了这种肿瘤带来的诊断挑战。一名71岁的女性在常规健康检查中偶然发现了无症状的前纵隔肿瘤。手术干预,随后进行病理和免疫组织化学分析,包括CK-pan,p63、p40和CD117分子,导致对胸腺基底细胞样癌的明确诊断。该病例强调了纵隔病变鉴别诊断的重要性,尤其是胸部CT表现为多房性胸腺囊肿的患者。剑突下电视胸腔镜手术可实现完整的肿瘤切除,创伤最小,术后预后良好。患者选择不进行进一步的放疗或化疗,她已经存活了八个月以上,没有复发。此病例报告有助于人们对胸腺基底细胞样癌的认识,一种罕见且潜在侵袭性的胸腺癌亚型。它强调了精确的外科技术和增强心胸外科医生和肿瘤学家的诊断敏锐度的必要性。
    This case report details a rare thymic basaloid carcinoma initially misinterpreted as a mediastinal teratoma, underscoring the diagnostic challenges posed by such tumors. A 71-year-old female presented with an asymptomatic anterior mediastinal tumor discovered incidentally during a routine health examination. Surgical intervention, followed by pathological and immunohistochemical analysis including CK-pan, p63, p40, and CD117 molecules, led to a definitive diagnosis of basaloid carcinoma of the thymus. This case highlights the critical importance of differential diagnosis in mediastinal lesions, especially those presenting with multilocular thymic cysts on chest CT. The subxiphoid video-assisted thoracoscopic surgery enabled complete tumor resection with minimal trauma and favorable postoperative outcomes. The patient opted against further radiotherapy or chemotherapy and she has survived for over eight months without recurrence. This case report contributes to the growing understanding of thymic basaloid carcinoma, a rare and potentially aggressive thymic carcinoma subtype. It emphasizes the necessity for precise surgical techniques and enhanced diagnostic acumen among cardiothoracic surgeons and oncologists.
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  • 文章类型: Journal Article
    背景:支气管囊肿是由气管支气管树的先天性异常出芽引起的。通常建议切除以避免并发症。纵隔支气管囊肿由于靠近重要结构而提出了独特的挑战。这项研究的目的是回顾我们对纵隔支气管囊肿的经验。方法:单机构回顾性评估2012年1月至2022年11月间所有纵隔支气管囊肿切除术。对患者的人口统计学进行了评估,包括诊断时的年龄,出现症状,成像检查,和囊肿特征。操作方法,并发症,并报告手术病理。结果:确定了5例患者。诊断时的年龄为18至27个月。没有患者被诊断为产前。所有患者在诊断时都有症状,包括咳嗽,喘息,和呼吸窘迫。三个囊肿是气管旁的,还有两个是食道旁的.手术年龄为26至30个月。所有支气管囊肿均通过胸腔镜成功切除。个别技术挑战包括缩小主支气管,防止肺隔离,显著的纵隔炎症,需要进行囊肿排空以描绘囊肿的范围,囊肿壁粘附于支气管或气管,需要冷解剖,和与被截肢的隆突有密切联系的组织茎。术中、术后无并发症发生。在所有情况下,手术病理均与支气管囊肿一致。平均住院时间为两天。结论:胸腔镜是小儿纵隔支气管囊肿切除术安全有效的方法。突出了某些技术演习,这可能有助于切除。
    Background: Bronchogenic cysts result from a congenital anomalous budding of the tracheobronchial tree. Resection is usually recommended to avoid complications. Mediastinal bronchogenic cysts present a unique challenge due to their proximity to vital structures. The purpose of this study is to review our experience with mediastinal bronchogenic cysts. Methods: A single-institution retrospective review evaluated all mediastinal bronchogenic cyst excisions between January 2012 and November 2022. Patient demographics were assessed, including age at diagnosis, presenting symptoms, imaging workup, and cyst characteristics. Operative approach, complications, and surgical pathology were reported. Results: Five patients were identified. Age at diagnosis ranged from 18 to 27 months. No patient was diagnosed prenatally. All patients had symptoms at the time of diagnosis, including cough, wheezing, and respiratory distress. Three cysts were paratracheal, and two were paraesophageal. Age at surgery ranged from 26 to 30 months. All bronchogenic cysts were successfully resected thoracoscopically. Individual technical challenges included narrowing of the mainstem bronchus preventing lung isolation, significant mediastinal inflammation, the necessity for cyst evacuation to delineate the extent of the cyst, adherence of cyst wall to bronchus or trachea requiring cold dissection, and a stalk of tissue with an intimate connection to the carina that was amputated. No intraoperative or postoperative complication occurred. Surgical pathology was consistent with a bronchogenic cyst in all cases. Median length of hospital stay was two days. Conclusion: Thoracoscopy is a safe and effective procedure for mediastinal bronchogenic cyst excision in children. Certain technical maneuvers are highlighted, which may facilitate resection.
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