■腹泻是第三世界的重要健康问题。确定引起腹泻的病原体对于预防和控制这种疾病的措施至关重要。苏丹也很少有腹泻的报道。我们的研究旨在确定特定原生动物病原体(溶组织内阿米巴,微小隐孢子虫。,和贾第虫)在喀土穆的儿童中,苏丹。
我们对2014年4月至12月间因急性腹泻住院的5岁以下儿童进行了横断面调查。收集腹泻粪便样本,C.parvum,使用多重实时PCR检查贾第鞭毛虫。
■本研究纳入了4137名急性腹泻儿童;腹泻患病率较高的是≤2岁以下(403,92.2%)。本研究中的男女比例为1:1.7。155例(35.5%)感染肠道寄生虫,合并感染16例(10.3%)。贾第鞭毛虫(18.8%)和小梭菌(15.8%)是最常见的寄生虫,其次是溶组织大肠杆菌(0.9)。2岁以下组(92.3%)和2-4岁组(7.3%)的寄生虫感染率最高,最低。男孩感染率(67.1%)高于女孩(32.9%)。雨季(8月至12月)原生动物感染发生率较高(92.2%),与旱季(4月至6月)相对应。(7.8%)。
■我们目前的研究表明,在喀土穆地区腹泻儿童中,贾第鞭毛虫和小梭菌的高患病率,以及多重实时方法在揭示病原原虫病原体方面的有用性。我们的结果强调了制定干预措施和控制策略以应对该地区儿童寄生虫性腹泻的必要性。
UNASSIGNED: Diarrhea is a significant health problem in the Third World. Identification of the pathogen that causes diarrhea is vital for measures to prevent and control this disease. There are also very few reports of diarrhea in Sudan. Our study aimed to determine the Prevalence of specific protozoan pathogens ( Entamoeba histolytica, Cryptosporidium parvum., and
Giardia spp) in children in Khartoum, Sudan.
UNASSIGNED: We conducted a cross-sectional survey among children under five years of age who were hospitalized with acute diarrhea between April and December 2014. Diarrheal stool samples were collected and E. histolytica, C. parvum, and
Giardia spp were examined using multiplex real-time PCR.
UNASSIGNED: Four hundred and thirty-seven children with acute diarrheawere included in this study; the higher Prevalence of diarrhea was in the age less than ≤ 2 years old (403,92.2%). The male-to-female ratio in this study was 1:1.7. infection with intestinal parasite was found in 155 (35.5%) cases, and co-infection was detected in 16 (10.3%) cases.
Giardia spp(18.8%) and C. parvum (15.8 %) were the most frequently identified parasites, followed by E. histolytica (0.9). The parasite infection rate was highest and lowest in the under 2-year-old group (92.3%) and the 2-4-year-old group (7.3%). The infection rate was higher in boys (67.1%) than in girls (32.9%). The incidence of protozoan infection was higher in the rainy season (August to December) (92.2%), corresponding with that in the dry Season (April to June). (7.8%).
UNASSIGNED: Our present study demonstrated the high prevalence of
Giardia spp and C. parvum in children with diarrhea in the Khartoum region and the usefulness of the multiplex real-time method in disclosing pathogenic protozoal agents. Our result highlighted the necessity of developing intervention measurement and control strategies to deal with childhood parasitic diarrhea in this region.