■习惯性必需氨基酸(EAA)摄入量与身体成分之间的关系,肌肉力量,美国老年人的身体功能并不明确。
■这项横断面研究评估了通常的EAA摄入量与身体成分之间的关联,肌肉力量,
■2001-2018年饮食研究食品和营养数据库(FNDDS)与美国农业部标准参考数据库链接,以访问FNDDS成分的现有氨基酸组成数据。将没有现有氨基酸组成数据的FNDDS成分与具有可用数据的相似成分代码匹配。通常的EAA,亮氨酸,赖氨酸,和含硫氨基酸(SAA;蛋氨酸+半胱氨酸)摄入量(g/d)来自2001-2018年国家健康和营养检查调查计算的个体≥65岁(n=10,843)。因变量包括通过等距握力测试测量的肌肉力量,体重指数(BMI),腰围,双能X线骨密度仪测量的四肢瘦肉量和全身脂肪量,和自我报告的身体功能(即,日常生活任务)。回归分析用于确定EAA,亮氨酸,赖氨酸,和SAA摄入量和功能健康结果。P<0.0013被认为是显著的。
■EAA,亮氨酸,赖氨酸,和SAA摄入量,与体力活动水平和通常的蛋白质摄入量,与男性或女性的肌肉力量或自我报告的身体功能或男性的身体组成无关。女性EAA摄入量与腰围呈正相关(β±SEM,2.1±0.6cm,P=0.0007)。赖氨酸摄入量与BMI(3.0±0.7kg/m2,P<0.0001)和腰围(7.0±1.7cm,P=0.0001)在女性中。
■习惯性EAA,亮氨酸,赖氨酸,和SAA摄入量,与体力活动水平和通常的蛋白质摄入量,与瘦体重无关,肌肉力量,或成人≥65岁的身体机能。然而,EAA摄入量,特别是赖氨酸,与老年女性肥胖程度呈正相关。该试验已在开放科学框架(https://doi.org/10.17605/OSF)中注册。IO/25V63)作为osf.io/25v63)。
UNASSIGNED: The relationships between habitual essential amino acid (EAA) intake and body composition, muscle strength, and physical function in older US adults are not well defined.
UNASSIGNED: This cross-sectional study evaluated associations between usual EAA intakes and body composition, muscle strength, and physical function in US adults ≥65 y.
UNASSIGNED: The Food and Nutrient Database for Dietary Studies (FNDDS) 2001-2018 was linked to the US Department of Agriculture Standard Reference database to access existing amino acid composition data for FNDDS ingredients. FNDDS ingredients without existing amino acid composition data were matched to similar ingredient codes with available data. Usual EAA, leucine, lysine, and sulfur-containing amino acid (SAA; methionine + cysteine) intakes (g/d) from National Health and Nutrition Examination Survey 2001-2018 were calculated for individuals ≥65 y (n = 10,843). Dependent variables included muscle strength measured by isometric grip test, body mass index (BMI), waist circumference, dual-energy X-ray absorptiometry-measured appendicular lean mass and whole-body fat mass, and self-reported physical function (that is, tasks of daily living). Regression analyses were used to determine covariate-adjusted relationships between EAA, leucine, lysine, and SAA intake and functional health outcomes. P < 0.0013 was considered significant.
UNASSIGNED: EAA, leucine, lysine, and SAA intakes, covaried with physical activity level and usual protein intake, were not associated with muscle strength or self-reported physical function in males or females or with body composition in males. EAA intakes were positively associated with waist circumference in females (β ± SEM, 2.1 ± 0.6 cm, P = 0.0007). Lysine intakes were positively associated with BMI (3.0 ± 0.7 kg/m2, P < 0.0001) and waist circumference (7.0 ± 1.7 cm, P = 0.0001) in females.
UNASSIGNED: Habitual EAA, leucine, lysine, and SAA intakes, covaried with physical activity level and usual protein intake, were not associated with lean mass, muscle strength, or physical function in adults ≥65 y. However, EAA intakes, particularly lysine, were positively associated with measures of adiposity in older females.This trial was registered with the Open Science Framework (https://doi.org/10.17605/OSF.IO/25V63) as osf.io/25v63).