Cardioversion

心脏复律
  • 文章类型: Journal Article
    在孕妇中,心律失常是心血管疾病的重要原因。随着怀孕期间心律失常的发生率继续增加,护理产科患者的麻醉师应该是妊娠期心律失常的专家。本文探讨了怀孕期间最常见的心律失常,包括风险因素,诊断,和管理策略。讨论了围产期监测和分娩镇痛建议。此外,心脏复律的管理,起搏器和植入式心脏复律除颤器的管理,并回顾了怀孕期间的高级心脏生命支持。
    Cardiac arrhythmias are responsible for a significant portion of cardiovascular disease among pregnant people. As the incidence of arrhythmias in pregnancy continues to increase, anesthesiologists who care for obstetric patients should be experts managing arrhythmias in pregnancy. This article examines the most common arrhythmias encountered in pregnancy, including risk factors, diagnosis, and management strategies. Peripartum monitoring and labor analgesia recommendations are discussed. Additionally, management of cardioversion, management of pacemakers and implantable cardioverter-defibrillators, and advanced cardiac life support in the setting of pregnancy is reviewed.
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  • 文章类型: Journal Article
    背景:直流电复律通常用于使心房颤动(AF)患者恢复窦性心律。心脏复律期间的胸压可以通过降低经胸阻抗和增加心脏能量递送来提高心脏复律的功效。
    目的:本研究旨在评估前后垫定位的房颤直流电复律期间前胸压的有效性和安全性。
    方法:这是一个多中心,调查员发起的,双盲,随机临床试验。招聘发生在2021年至2023年。随访直到出院。在新南威尔士州的3个中心进行了招聘,澳大利亚。纳入标准为年龄≥18岁,房颤复律转诊,抗凝治疗3周或经食管超声心动图排除左心耳血栓。排除标准是其他需要复律的心律失常,如房扑和房性心动过速。在第一次电击的心脏复律过程中,干预臂接受了胸压。主要疗效结果是每次患者相遇所需的总焦耳数。次要疗效结果包括首次电击成功,经胸阻抗,心脏复律成功,和复律后30分钟的窦性心律。
    结果:共有311名患者被随机分组,153控制,158干预。控制臂与干预臂每次相遇施加的总焦耳数没有差异(355.0±301Jvs413.8±347J;P=0.19)。第一次电击成功没有区别,提供的总冲击,平均阻抗,和心脏复律成功。
    结论:本研究不支持常规应用胸压在心房颤动中的直流电复律(PRESSURE-AF[研究胸压在心房颤动中直流电复律的疗效:一项随机对照试验];ACTRN12620001028998)。
    BACKGROUND: Direct current cardioversion is frequently used to return patients with atrial fibrillation (AF) to sinus rhythm. Chest pressure during cardioversion may improve the efficacy of cardioversion through decreasing transthoracic impedance and increasing cardiac energy delivery.
    OBJECTIVE: This study aimed to assess the efficacy and safety of upfront chest pressure during direct current cardioversion for AF with anterior-posterior pad positioning.
    METHODS: This was a multicenter, investigator-initiated, double-blinded, randomized clinical trial. Recruitment occurred from 2021 to 2023. Follow-up was until hospital discharge. Recruitment occurred across 3 centers in New South Wales, Australia. Inclusion criteria were age ≥18 years, referred for cardioversion for AF, and anticoagulation for 3 weeks or transesophageal echocardiography excluding left atrial appendage thrombus. Exclusion criteria were other arrhythmias requiring cardioversion, such as atrial flutter and atrial tachycardia. The intervention arm received chest pressure during cardioversion from the first shock. The primary efficacy outcome was total joules required per patient encounter. Secondary efficacy outcomes included first shock success, transthoracic impedance, cardioversion success, and sinus rhythm at 30 minutes post cardioversion.
    RESULTS: A total of 311 patients were randomized, 153 to control and 158 to intervention. There was no difference in total joules applied per encounter in the control arm vs intervention arm (355.0 ± 301 J vs 413.8 ± 347 J; P = 0.19). There was no difference in first shock success, total shocks provided, average impedance, and cardioversion success.
    CONCLUSIONS: This study does not support the routine application of chest pressure for direct current cardioversion in atrial fibrillation (PRESSURE-AF [Investigating the Efficacy of Chest Pressure for Direct Current Cardioversion in Atrial Fibrillation: A Randomized Controlled Trial]; ACTRN12620001028998).
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  • 文章类型: Case Reports
    心房颤动(AF)是在其他健康的新生马驹中很少报道的心律失常,文献中描述的使用普鲁卡因胺给药的单例心脏复律。由于尝试护理时不规则的快速性心律失常和闭锁不良,两只新生儿纯种小马被送到了一家马医院。历史,体检,包括心电图和超声心动图在内的初始诊断测试证实房颤无结构性心脏病。第1只马驹在静脉注射美托洛尔和奎尼丁治疗后转变为正常窦性心律。第二只马驹在单次静脉注射美托洛尔后转变为正常窦性心律,用于速率控制。转换后,情绪和护理行为明显改善。2只小马驹的心率和窦性心律正常,持续6周,直到第1只小马驹安乐死,第2只小马驹持续2年。心率控制和心脏复律应被视为新生儿马驹持续性单发房颤的治疗方法。
    Atrial fibrillation (AF) is a rarely reported arrhythmia in otherwise healthy newborn foals, with a single case of cardioversion using procainamide administration described in the literature. Two neonatal Thoroughbred colts were presented to an equine hospital because of an irregularly irregular tachyarrhythmia and poor latching when trying to nurse. History, physical examination, and initial diagnostic testing including ECG and echocardiography confirmed AF without structural heart disease. The 1st foal converted into normal sinus rhythm after treatment with IV metoprolol and quinidine. The 2nd foal converted to normal sinus rhythm after a single IV dose of metoprolol, intended for rate control. Demeanor and nursing behavior improved markedly after conversion. The 2 foals had normal heart rates and sinus rhythm that persisted for 6 weeks until euthanasia in the 1st foal and for 2 years in the 2nd foal. Rate control and cardioversion should be considered as a treatment for persistent lone AF in neonatal foals.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    尽管在房颤(AF)患者中恢复和维持窦性心律(SR)具有长期益处,很少有研究调查SR恢复后立即对急性血流动力学的益处.因此,我们调查了从AF复律至SR后最初几分钟内是否发生了血流动力学变化.
    我们回顾性招募了145例房颤患者,并将他们分为房颤前的组,其中包括在肺静脉隔离期间通过电复律恢复SR的患者(PVI;n=74)和对照组,其中包括在整个手术期间处于SR的患者(n=71)。根据房颤分类将房颤前期组细分为亚组(阵发性房颤(PAF),持久性AF(PerAF),和长期持续性房颤(LSPAF)),并根据房颤心率(HR)分为四分位数。经中隔穿刺(预先测量)和PVI后从左心房撤出(后测量)后立即测量平均动脉压(MAP)和左心房压(LAP)。通过从测量后(MAPpost和LAPpost)中减去测量前(MAPpre和LAPpre)来计算测量前和测量后(ΔMAP和ΔLAP)之间的MAP和LAP的变化。
    在预AF组中,从复律到测量后的时间为19±16分钟.当ΔMAP和ΔLAP与对照组比较时,ΔMAP明显较小(4.9±17.8vs.11.0±14.2mmHg,分别为;P=0.025),两组间ΔLAP无显著差异。在亚组分析中,尽管ΔLAP在AF类型之间没有显着差异,与PerAF和LSPAF组相比,PAF组的ΔMAP显着增加(24.0±18.5vs.3.1±16.8和4.5±18.1mmHg,分别;P=0.042)。最低四分位数中的HRpre,第二,第三,最高的AF-HR约为每分钟58、74、86和109次(bpm),分别。AF-HR四分位数组之间的ΔLAP和ΔMAP没有显着差异。
    在PAF患者中,心房收缩可能很快恢复,这导致SR恢复后立即改善血液动力学。至于AF-HR,在大约<109bpm时,心室舒张充盈没有明显损害。
    UNASSIGNED: Although the restoration and maintenance of sinus rhythm (SR) in patients with atrial fibrillation (AF) have long-term benefits, few studies have investigated the acute hemodynamic benefits immediately after SR restoration. Therefore, we investigated whether hemodynamic changes occurred in the first few minutes after cardioversion from AF to SR.
    UNASSIGNED: We retrospectively enrolled 145 patients with AF and divided them into a pre-AF group comprising patients in whom SR was restored by electrical cardioversion during pulmonary vein isolation (PVI; n = 74) and a control group comprising patients who were in SR throughout the procedure (n = 71). The pre-AF group was subdivided into subgroups according to AF classification (paroxysmal AF (PAF), persistent AF (PerAF), and long-standing persistent AF (LSPAF)) and into quartiles based on the AF-heart rate (HR). The mean arterial pressure (MAP) and left atrial pressure (LAP) were measured immediately after transseptal puncture (pre-measurement) and before withdrawal from the left atrium after PVI (post-measurement). The changes in MAP and LAP between the pre- and post-measurement (ΔMAP and ΔLAP) were calculated by subtracting the pre-measurements (MAPpre and LAPpre) from the post-measurements (MAPpost and LAPpost).
    UNASSIGNED: In the pre-AF group, the time from cardioversion to post-measurement was 19 ± 16 min. When ΔMAP and ΔLAP were compared with the control group, ΔMAP was significantly smaller (4.9 ± 17.8 vs. 11.0 ± 14.2 mm Hg, respectively; P = 0.025), and ΔLAP was not significantly different between the groups. In the subgroup analyses, although ΔLAP was not significantly different among AF types, ΔMAP was significantly increased in the PAF group compared to the PerAF and LSPAF groups (24.0 ± 18.5 vs. 3.1 ± 16.8 and 4.5 ± 18.1 mm Hg, respectively; P = 0.042). The HRpre in the quartiles with the lowest, second, third, and highest AF-HR were approximately 58, 74, 86, and 109 beats per minute (bpm), respectively. The ΔLAP and ΔMAP were not significantly different among the AF-HR quartile groups.
    UNASSIGNED: In patients with PAF, atrial contractions may resume quickly, which leads to hemodynamic improvement immediately after SR restoration. As for AF-HR, there was no significant impairment of ventricular diastolic filling at approximately < 109 bpm.
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  • 文章类型: Journal Article
    目的:治疗近期房颤(AF)是通过心脏复律(CV)达到窦性心律(SR)。然而,SR通常是自发恢复的,使预定的入院不必要,并导致医疗资源的滥用。新兴的医疗技术允许准确的心律监测。这项研究在这些患者中评估了这项技术,防止不必要的录取,并提供更早的管理。
    方法:设计了一项多中心研究,包括计划进行选择性电CV的房颤患者。患者每天向中央CoreLab提交心电图记录,一天两次,每当他们出现症状时,直到CV(自发或预定)和一周后。每当检测到自发转化为SR时,研究者被联系以确认SR并中止入院.使用感知效用测试评估患者满意度,便利性,和可访问性。
    结果:纳入74例患者(年龄62±10岁)。22例患者(30%)表现为自发转换为SR。总共阻止了22例入院和16例经食管超声心动图检查。在52例因CV入院的患者中,45(88%)在SR中出院。在转换为SR(自发或电)后的随访期间,房颤复发24例(34%).在随访结束时,51例患者(69%)仍处于SR状态。CoreLab接受了93%的预期ECG传输。患者的总体满意度评分为9.1/10。
    结论:用于心律监测的数字设备可以优化安排择期CV的房颤患者的管理,防止不必要的入院,并提供更合理的医疗资源使用。
    OBJECTIVE: Management in recent-onset atrial fibrillation (AF) is to achieve sinus rhythm (SR) by cardioversion (CV). However, frequently SR is spontaneously restored, making scheduled admission unnecessary and causing misutilization of healthcare resources. Emerging medical technology allows accurate heart rhythm monitoring. This study evaluated this technology in these patients, preventing unnecessary admission and providing an earlier management.
    METHODS: A multicenter study was designed including patients with AF scheduled for elective electrical CV. Patients submitted ECG recordings to a central CoreLab daily, twice a day and whenever they present symptoms, until CV (spontaneous or scheduled) and a week afterwards. Whenever a spontaneous conversion to SR was detected, investigators were contacted to confirm SR and abort admission. Patients\' satisfaction was evaluated using a test for perceived utility, convenience, and accessibility.
    RESULTS: 74 patients were enrolled (age 62±10 years). Twenty-two patients (30%) showed spontaneous conversion to SR. A total of 22 admissions and 16 transesophageal echocardiograms were prevented. Among 52 patients admitted for CV, 45 (88%) were discharged in SR. During follow-up after conversion to SR (spontaneous or electrical), recurrences of AF occurred in 24 patients (34%). At the end of the follow-up 51 patients (69%) remained in SR. The CoreLab received 93% of the expected ECG transmissions. Patient\'s overall satisfaction score was 9.1 over 10.
    CONCLUSIONS: Digital devices for heart rhythm monitoring can optimize the management of AF patients scheduled for elective CV, preventing unnecessary admissions and providing a more rational use of healthcare resources.
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  • 文章类型: Journal Article
    心房颤动(AF)是术后最常见的心律失常。我们旨在调查术后房颤(POAF)的发生率并确定其预测因子,特别关注炎症标志物。
    我们进行了一项回顾性单三级中心队列研究,包括2016年1月至2020年1月期间接受大手术的连续成年患者。根据手术类型将患者分为四个亚组。
    在53,387名患者中(79.4%为男性,年龄64.5±9.5岁),POAF发生在570例(1.1%),术后平均潜伏期为3.4±2.6天。平均13.7±8.4天后,90例患者死亡(0.17%)。接受肺和心血管手术的患者的28天无心律失常生存率较低(p<.001)。发生POAF的患者C反应蛋白(CRP)水平较高(0.70±0.03vs.0.40±0.01log10毫克/分升;p<.001)。在多变量Cox回归分析中,调整混杂因素,CRP是POAF的独立预测因子[HR每1mg/dL增加的对数标度=1.81(95%CI1.18-2.79);p=.007]。此外,POAF的独立预测因素也是年龄(HR/1年增加=1.06(95%CI1.04-1.08);I<.001),肺和心血管手术(HR23.62;(95%CI5.65-98.73);p<.001),腹部和食管手术(HR6.26;95%CI1.48-26.49;p=.013)。
    肺和心血管手术的POAF风险最高。CRP是POAF的独立预测因子,术后炎症可能是心律失常病理生理学的主要驱动因素。
    UNASSIGNED: Atrial fibrillation (AF) represents the most common arrhythmia in the postoperative setting. We aimed to investigate the incidence of postoperative AF (POAF) and determine its predictors, with a specific focus on inflammation markers.
    UNASSIGNED: We performed a retrospective single tertiary center cohort study including consecutive adult patients who underwent a major surgical procedure between January 2016 and January 2020. Patients were divided into four subgroups according to the type of surgery.
    UNASSIGNED: Among 53,387 included patients (79.4% male, age 64.5 ± 9.5 years), POAF occurred in 570 (1.1%) with a mean latency after surgery of 3.4 ± 2.6 days. Ninety patients died (0.17%) after a mean of 13.7 ± 8.4 days. The 28-day arrhythmia-free survival was lower in patients undergoing lung and cardiovascular surgery (p < .001). Patients who developed POAF had higher levels of C-reactive protein (CRP) (0.70 ± 0.03 vs. 0.40 ± 0.01 log10 mg/dl; p < .001). In the multivariable Cox regression analysis, adjusting for confounding factors, CRP was an independent predictor of POAF [HR per 1 mg/dL increase in log-scale = 1.81 (95% CI 1.18-2.79); p = .007]. Moreover, independent predictors of POAF were also age (HR/1 year increase = 1.06 (95% CI 1.04-1.08); I < .001), lung and cardiovascular surgery (HR 23.62; (95% CI 5.65-98.73); p < .001), and abdominal and esophageal surgery (HR 6.26; 95% CI 1.48-26.49; p = .013).
    UNASSIGNED: Lung and cardiovascular surgery had the highest risk of POAF in the presented cohort. CRP was an independent predictor of POAF and postsurgery inflammation may represent a major driver in the pathophysiology of the arrhythmia.
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  • 文章类型: Case Reports
    Takotsubo心肌病,也被称为应激性心肌病或“心碎综合征”,“是一种罕见且可逆的疾病,其特征是短暂性左心室功能障碍。它通常是由急性情绪或身体压力引发的。这里,我们介绍了一例独特的中医病例,该病例发生在1名77岁女性因持续性和有症状的心房颤动复律后.患者接受了简单的心脏复律,最近的影像学显示完整的整体收缩功能。她在手术后四天出现了胸痛,呼吸急促,和外周水肿。重复超声心动图显示心脏功能显着下降,射血分数为20-25%。患者再次入院,并接受静脉利尿剂治疗。症状在三天内缓解,患者出院前影像学显示心功能改善。
    Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy or \"broken heart syndrome,\" is a rare and reversible condition characterized by transient left ventricular dysfunction. It is typically triggered by acute emotional or physical stressors. Here, we present a unique case of TCM occurring in a 77-year-old woman following cardioversion for persistent and symptomatic atrial fibrillation. The patient underwent uncomplicated cardioversion with recent imaging showing intact global systolic function. She presented four days post-procedure for chest pain, shortness of breath, and peripheral edema. A repeat echocardiogram showed a marked decrease in cardiac function evidenced by an ejection fraction of 20-25%. The patient was readmitted and managed with IV diuretics. Symptoms resolved within three days and the patient showed improved cardiac function on imaging prior to discharge.
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  • 文章类型: Journal Article
    直流电复律(DCCV)用作房颤(AF)的选择性和紧急心律控制。我们旨在探讨使用体表标测(BSM)在窦性心律期间测量的P波参数在预测12个月时持续性房颤(persAF)的成功DCCV中的作用。
    这项病例对照研究包括56名18岁以上的男性,他们接受了DCCV治疗。使用128个单极性引线进行AF的DCCV后的P波参数收集。使用1-50Hz的带通滤波器。校正P波持续时间(PWDc),P波振幅,测量P波离散度以预测12个月的结局和复发时间。
    平均年龄为64±4岁,23例(44%)患者服用胺碘酮。12个月的成功率为44%(n=23),其余患者在2.6±0.4个月后恢复为房颤。整个队列中成功和失败的DCCV与未使用胺碘酮的患者之间的参数相当。服用胺碘酮的患者,手臂失败的患者的PWDc高于手臂成功的患者(188vs.150ms,P=0.04)。胺碘酮队列中PWDc的受试者操作员特征曲线分析显示,曲线下面积(AUC)为0.75,P=0.049。>161ms的复发截止具有69%的灵敏度和100%的特异性,风险比为10.7,P=0.004。这些参数不能预测复发时间。
    服用胺碘酮的患者,使用BSM测得的PWDc升高与因persAF而在DCCV后12个月时房颤复发率升高相关。
    UNASSIGNED: Direct current cardioversion (DCCV) is used as elective and emergency rhythm control for atrial fibrillation (AF). We aimed to explore the role of P-wave parameters measured during sinus rhythm using body surface mapping (BSM) in predicting successful DCCV for persistent atrial fibrillation (persAF) at 12 months.
    UNASSIGNED: This case-control study included 56 males >18 years old who underwent DCCV for persAF. P-wave parameter collection after DCCV for AF was done using 128 unipolar leads. A band-pass filter of 1-50 Hz was utilised. Corrected P-wave duration (PWDc), P-wave amplitude, and P-wave dispersion were measured to predict 12-month outcomes and time of recurrence.
    UNASSIGNED: The mean age was 64 ± 4 years, and 23 patients (44%) were on amiodarone. The 12-month success rate was 44% (n = 23), while the rest reverted to AF after 2.6 ± 0.4 months. The parameters were comparable between successful and failed DCCV in the entire cohort and patients not on amiodarone. In patients on amiodarone, patients with failed arms had higher PWDc than those with successful arms (188 vs. 150 ms, P = 0.04). Receiver operator characteristic curve analysis for PWDc in the amiodarone cohort showed an area under the curve (AUC) of 0.75 and P = 0.049. A recurrence cut-off >161 ms had a sensitivity of 69% and a specificity of 100%, with a hazard ratio of 10.7, P = 0.004. The parameters were not predictive of the time of recurrence.
    UNASSIGNED: In patients on amiodarone, increased PWDc measured using BSM was associated with higher AF recurrence at 12 months following DCCV for persAF.
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  • 文章类型: Case Reports
    心房颤动(AF)是一种以不规则心律为特征的普遍心脏疾病。传统的非侵入性诊断技术,虽然有用,在为治疗计划提供全面信息方面存在局限性。为了解决这个差距,机电周期长度映射(ECLM),一种基于非侵入性超声心动图的技术,已经成为一种有希望的方法。机电周期长度标测提供了对心房机电激活率标测的定量和空间特异性见解。从而提高我们对房颤患者心律失常疾病进展的认识。
    在这种情况下,我们介绍了2例患者病例,证明ECLM在监测和评估房性心律失常治疗反应方面的潜在效用.第一例涉及一名患有持续性房颤的61岁男性,他接受了多次手术,包括直流电复律(DCCV)和射频消融。在三次不同的DCCV遭遇中,术前和术后进行ECLM扫描,结果显示DCCV后心律失常触发因素的定位和不完全消除,作为房颤复发的早期指标。第二例涉及一名71岁的男性阵发性房颤,他也接受了心脏复律和消融手术。机电周期长度标测成像显示每次相遇后心律失常触发因素的逐渐减少和消除,导致窦性心律的长期维持。
    本病例系列的研究结果凸显了ECLM作为一种非侵入性成像工具的潜力,用于长期监测和评估房颤患者的即时和长期治疗反应。ECLM与标准超声心动图的整合有望指导临床决策并改善患者治疗房颤的结果。
    UNASSIGNED: Atrial fibrillation (AF) is a prevalent cardiac condition characterized by irregular heart rhythm. Conventional non-invasive diagnostic techniques, while useful, have limitations in providing comprehensive information for treatment planning. To address this gap, electromechanical cycle length mapping (ECLM), a non-invasive echocardiography-based technique, has emerged as a promising approach. Electromechanical cycle length mapping offers quantitative and spatially specific insights into atrial electromechanical activation rate mapping, thereby enhancing our understanding of arrhythmia disease progression in AF patients.
    UNASSIGNED: In this case series, we present two patient cases demonstrating the potential utility of ECLM in monitoring and evaluating treatment responses in atrial arrhythmia. The 1st case involved a 61-year-old male with persistent AF who underwent multiple procedures, including direct current cardioversion (DCCV) and radiofrequency ablation. Over three different DCCV encounters, pre- and post-procedure ECLM scans were performed, and the results showed the localization and incomplete elimination of arrhythmic triggers post-DCCV, which were used as early indicators of AF recurrence. The 2nd case involved a 71-year-old male with paroxysmal AF who also underwent cardioversion and ablation procedures. Electromechanical cycle length mapping imaging demonstrated a progressive reduction and elimination of arrhythmia triggers after each encounter, resulting in long-term maintenance of sinus rhythm.
    UNASSIGNED: The findings from this case series highlight the potential of ECLM as a non-invasive imaging tool for long-term monitoring and evaluating immediate and long-term treatment responses in AF patients. The integration of ECLM with standard echocardiograms holds promise in guiding clinical decisions and improving patient outcomes in managing atrial fibrillation.
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