Atrial tachycardia

心房心动过速
  • 文章类型: Journal Article
    背景:心外膜马歇尔束(MB)经常用于房颤(AF)消融后的左心房心动过速(LAT),并进行肺静脉隔离和基质修饰。
    目的:本研究试图对MB介导的LAT的不同激活模式以及相应的电生理特性进行分类。
    方法:自2019年至2021年,通过超高密度标测和夹带法诊断房颤消融术后房性心动过速(ATs)28例。在选定的病例中,还进行了马歇尔静脉(VOM)的插管和标测以及MB区域的心外膜标测,以进一步证明其机制。
    结果:通过MB确定了关键峡部的三种激活模式:1)二尖瓣周围宏观折返(PMLAT)(n=20,71.4%);2)左心耳(LAA)相关折返(n=5,17.9%);3)左肺静脉(LPV)相关折返(n=3,10.7%)。在18名患者中,沿着先前的心内膜LA脊阻断线观察到的特征性三电位由近场双电位和远场MB电位组成.在VOM插管(19例)或心外膜标测(5例)的24例患者中进一步描述了这些发现。VOM的乙醇输注导致20/28例患者的AT终止。
    结论:房颤消融术后不同类型的MB介导的LATs可通过超高密度标测进行鉴定。在VOM内注入乙醇可有效消除这些心动过速。
    BACKGROUND: Epicardial Marshall bundle (MB) are frequently utilized in left atrial tachycardias (LATs) post atrial fibrillation (AF) ablation with pulmonary vein isolation and substrate modification.
    OBJECTIVE: This study sought to classify different activation patterns of MB mediated LATs and the corresponding electrophysiological characteristics.
    METHODS: From 2019 to 2021, 28 cases of atrial tachycardias(ATs)post-AF-ablation were diagnosed as MB-mediated LATs by ultra-high density mapping and entrainment. Cannulation and mapping in the vein of Marshall (VOM) and epicardial mapping in the MB region were also performed in selected cases to further prove the mechanism.
    RESULTS: Three activation patterns were identified with a critical isthmus via MB: 1)peri-mitral macro-reentry (PM LAT) (n=20, 71.4%); 2) Left atrial appendage (LAA)-related reentry (n=5, 17.9%); and 3) Left pulmonary vein (LPV)-related reentry (n=3,10.7%). In 18 patients, a characteristic triple potential observed along the previously endocardial LA ridge block line was composed of near-field double potentials and far-field MB potential. These findings were further delineated in 24 patients with either cannulation in the VOM (19 patients) or epicardial mapping(5 patients). Ethanol infusion of the VOM resulted in AT termination in 20/28 patients.
    CONCLUSIONS: Different types of MB-Mediated LATs post AF-ablation could be identified by ultra- high density mapping. Ethanol infusion within the VOM was effective in eliminating these tachycardias.
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  • 文章类型: Journal Article
    目的:脉冲场消融(PFA)是一种新兴的肺静脉隔离(PVI)技术。初步数据显示高安全性和有效性。与已建立的PVI能源相比,长期PVI耐久性和再传导模式的数据很少。我们将第一次脉冲场消融(PFA)后重复消融程序的结果与第一次基于冷冻球囊消融(CBA)的PVI后重复消融程序的结果进行比较。
    方法:550例连续入组患者接受PFA或CBA指数PVI。分析了有症状的房性心律失常复发患者的重复消融。
    结果:共有22/191(12%)患者在指数PFA-PVI后和44/359(12%)患者在CBA-PVI后接受了重复消融。通过多极螺旋标测导管在每个PV处检测到任何肺静脉(PV)的重建,并仔细评估PV电位,并通过3D标测在PFA-PVI后的16/22患者(73%)和CBA-PVI后的33/44(75%)(p=1.000)。在PFA-PVI后最初分离的82个PV中,31例(38%)正在重新进行;在CBA-PVI后的169个孤立的PVs中,63例(37%)正在重新进行(p=0.936)。PFA(5/22;23%)和CBA(7/44;16%;p=0.515)后患者的临床房性心动过速发生相似。与CBA-PVI(5/44;11%;p=0.023)相比,PFA-(8/22;36%)后更频繁地设置屋顶线。重复消融时,重复手术持续时间(PFA:87[76,123]min;CBA:93[75,128]min;p=0.446)相似,透视时间(PFA:11[9,14]min;CBA:11[8,14]min;p=0.739)在重复消融时组间相等。
    结论:在先前基于PFA或CBA的PVI后重复消融期间,电PV复导率和模式相似。
    OBJECTIVE: Pulsed-field ablation (PFA) is an emerging technology to perform pulmonary vein isolation (PVI). Initial data demonstrated high safety and efficacy. Data on long-term PVI durability and reconduction patterns in comparison to established energy sources for PVI are scarce. We compare findings in repeat ablation procedures after a first PFA to findings in repeat ablation procedures after a first cryoballoon ablation (CBA) based PVI.
    RESULTS: A total of 550 consecutively enrolled patients underwent PFA or CBA index PVI. Repeat ablations in patients with symptomatic atrial arrhythmia recurrences were analysed. A total of 22/191 (12%) patients after index PFA-PVI and 44/359 (12%) after CBA-PVI underwent repeat ablation. Reconduction of any pulmonary vein (PV) was detected by multipolar spiral mapping catheter at each PV with careful evaluation of PV potentials and by 3D-mapping in 16/22 patients (73%) after PFA-PVI and in 33/44 (75%) after CBA-PVI (P = 1.000). Of 82 initially isolated PVs after PFA-PVI, 31 (38%) were reconducting; of 169 isolated PVs after CBA-PVI, 63 (37%) were reconducting (P = 0.936). Clinical atrial tachycardia occurred similarly in patients after PFA (5/22; 23%) and CBA (7/44; 16%; P = 0.515). Roof lines were set more often after PFA- (8/22; 36%) compared with CBA-PVI (5/44; 11%; P = 0.023). Repeat procedure duration [PFA: 87 (76, 123) min; CBA: 93 (75, 128) min; P = 0.446] was similar and fluoroscopy time [PFA: 11 (9, 14) min; CBA: 11 (8, 14) min; P = 0.739] equal between groups at repeat ablation.
    CONCLUSIONS: During repeat ablation after previous PFA- or CBA-based PVI, electrical PV-reconduction rates and patterns were similar.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    新生儿狼疮可能与严重的心脏传导问题有关,包括高度或完全房室传导阻滞,在新生儿期需要立即植入起搏器。然而,新生儿狼疮的心脏表现可能超出房室传导阻滞。我们的病例是一名足月女性新生儿,出生后出现胎儿心律失常和心动过缓,心率约为每分钟70-75次。由于母体和新生儿抗SSA/Ro抗体阳性,后来诊断为新生儿狼疮。最初考虑高度房室传导阻滞,但通过心电图的详细评估证实了伴有传导阻滞的双联性早搏(PAC)。表现为不固定的PP间期和固定的RR间期。新生儿23天时发生房性心动过速(AT)。区分高度AV阻滞与具有阻滞的PAC的关键点是PP间隔。PP间隔在高度AV阻滞中是固定的,在具有阻滞的PAC中是不固定的。对于患有心动过缓的新生儿,需要仔细的鉴别诊断,因为它可能导致非常不同的管理。我们的案例很好地说明了为什么需要区分这些心律失常。此外,我们的病例可能是新生儿狼疮合并AT的首例.
    Neonatal lupus may be associated with severe cardiac conduction problems, including high-degree or complete atrioventricular (AV) block, necessitating immediate pacemaker implantation during the neonatal period. However, cardiac manifestations of neonatal lupus may extend beyond AV block. Our case was a full-term female neonate, who presented with fetal arrhythmia and bradycardia with a heart rate of approximately 70-75 beats per minute after birth. Neonatal lupus was diagnosed later due to positive maternal and neonatal anti-SSA/Ro antibody. High-degree AV block was considered initially but bigeminy premature atrial contractions (PACs) with block was confirmed through a detailed evaluation of an electrocardiogram, which demonstrated unfixed PP intervals and fixed RR intervals. Atrial tachycardia (AT) developed when the neonate was 23 days old. The key point that differentiates high-degree AV block from PACs with block is the PP interval. The PP interval is fixed in high-degree AV block and unfixed in PACs with block. Careful differential diagnosis is required in neonates with bradycardia because it may lead to very different management. Our case presents a good illustration of why these arrhythmias need to be differentiated. Furthermore, our case may be the first of neonatal lupus with AT.
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  • 文章类型: Journal Article
    在心脏电生理学领域,有一个普遍的愿望:发现一种完美的室上性心动过速(SVT)的诊断方法。这不仅仅是一个愿望,而是一个共同的冒险之旅。为了提高诊断准确性并达到足够的灵敏度和特异性,已经提出了许多诊断策略。然而,每种方法都有其局限性,并促使人们寻找新的诊断技术.这种不断发现和完善的循环,我们将其命名为“SVTQuest”,并按时间顺序排列。这种诊断狭窄QRS心动过速的冒险分为3个步骤:步骤1涉及根据V-A-V或V-A-A-V反应等观察结果将房性心动过速与其他室上性心动过速区分开来。ΔAA间隔,VA连接,最后的夹带序列,以及对心房刺激的反应。步骤2的重点是根据观察结果,例如在His折射期间室性早搏后的心动过速重置,将直行的往复式心动过速与房室结折返性心动过速区分开。未校正/校正起搏后间期,不同的心室夹带,他的捕获,过渡带分析,和完全起搏早产。步骤3根据V-V-A反应等观察结果,表征了隐匿性结室/结束通路和His-心室通路相关的心动过速。Δ心房His间隔,和矛盾的复位现象。没有适合所有情况的单一诊断操作。因此,在病例中应用多次操作的能力使操作员能够积累证据以做出可能的诊断。让我们开始这次冒险吧!
    In the field of cardiac electrophysiology, there is a universal desire: the discovery of a flawless diagnostic maneuver for supraventricular tachycardias (SVTs). This is not merely a wish but a shared odyssey. To improve diagnostic accuracy and achieve sufficient sensitivity and specificity, numerous diagnostic maneuvers have been proposed. However, each has its limitations and prompts a search for new diagnostic techniques. This continuous cycle of discovery and refinement, which we titled \"SVT Quest\" is reviewed in chronological sequence. This adventure in diagnosing narrow QRS tachycardia unfolds in 3 steps: Step 1 involves differentiating atrial tachycardia from other SVTs based on the observations such as V-A-V or V-A-A-V response, ΔAA interval, VA linking, the last entrainment sequence, and response to the atrial extrastimulus. Step 2 focuses on differentiating orthodromic reciprocating tachycardia from atrioventricular nodal reentrant tachycardia based on the observations such as tachycardia reset upon the premature ventricular contraction during His refractoriness, uncorrected/corrected postpacing interval, differential ventricular entrainment, orthodromic His capture, transition zone analysis, and total pacing prematurity. Step 3 characterizes the concealed nodoventricular/nodofascicular pathway and His-ventricular pathway-related tachycardia based on observations such as V-V-A response, ΔatrioHis interval, and paradoxical reset phenomenon. There is no single diagnostic maneuver that fits all scenarios. Therefore, the ability to apply multiple maneuvers in a case allows the operator to accumulate evidence to make a likely diagnosis. Let\'s embark on this adventure!
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  • 文章类型: Case Reports
    背景:脉冲场消融(PFA)是一种新型的非热能,具有独特的功能,可以超越肺静脉消融,比如组织选择性或接近性,而不是接触依赖性。
    结果:我们报告了3例右局灶性房性心动过速,起因于上腔静脉交界处和冠状末端,与膈神经关系密切,使用设计用于肺静脉隔离的市售PFA导管有效消融,无附带损害。
    结论:PFA可用于治疗累及膈神经附近的右心房心动过速,避免需要复杂的神经保护策略。
    BACKGROUND: Pulsed-field ablation (PFA) is a novel nonthermal energy that shows unique features that can be of use beyond pulmonary vein ablation, like tissue selectivity or proximity rather than contact dependency.
    RESULTS: We report three cases of right focal atrial tachycardias arising from the superior cavoatrial junction and the crista terminalis, in close relationship with the phrenic nerve, effectively ablated using a commercially available PFA catheter designed for pulmonary vein isolation without collateral damage.
    CONCLUSIONS: PFA can be useful for treating right atrial tachycardias involving sites near the phrenic nerve, avoiding the need for complex nerve-sparing strategies.
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  • 文章类型: Journal Article
    导管消融(CA)被认为是根除持续性和异常心律失常的最有效方法之一。然而,在某些情况下,这些心律失常没有得到适当的治疗,导致它们复发。如果不及时治疗,它们可能会导致中风等并发症,心力衰竭,或死亡。直到最近,诊断CA后复发性心律失常的主要技术是在随访期间对心脏影像学和心电图上的心律失常引起的变化易感的发现。或患者在消融后报告心悸或胸部不适。然而,这些后续行动可能既耗时又昂贵,他们可能并不总是确定复发的根本原因。随着人工智能(AI)的引入,这些后续访问可以有效缩短,和改进的方法来预测他们的消融程序后复发心律失常的可能性可以开发。AI可以分为两类:机器学习(ML)和深度学习(DL),后者是ML的子集。ML和DL模型已在多项研究中使用,以证明其使用临床变量预测和识别心律失常的能力。电生理特性,和从成像数据中提取的趋势。由于AI能够计算大量数据并检测电信号和心脏图像的细微变化,因此已被证明是心脏病专家的宝贵帮助。这可能会增加CA后复发性心律失常的风险。尽管这些涉及人工智能的研究产生了与人类干预相当或优于人类干预的有希望的结果,他们主要关注心房颤动,而房扑(AFL)和房性心动过速(AT)是相对较少的AI研究.因此,这篇综述的目的是研究人工智能算法的相互作用,电生理特性,成像数据,风险评分计算器,和临床变量在预测消融术后的心律失常。这篇评论还将讨论这些算法的实现,以实现CA后AFL和AT复发的检测和预测。
    Catheter ablation (CA) is considered as one of the most effective methods technique for eradicating persistent and abnormal cardiac arrhythmias. Nevertheless, in some cases, these arrhythmias are not treated properly, resulting in their recurrences. If left untreated, they may result in complications such as strokes, heart failure, or death. Until recently, the primary techniques for diagnosing recurrent arrhythmias following CA were the findings predisposing to the changes caused by the arrhythmias on cardiac imaging and electrocardiograms during follow-up visits, or if patients reported having palpitations or chest discomfort after the ablation. However, these follow-ups may be time-consuming and costly, and they may not always determine the root cause of the recurrences. With the introduction of artificial intelligence (AI), these follow-up visits can be effectively shortened, and improved methods for predicting the likelihood of recurring arrhythmias after their ablation procedures can be developed. AI can be divided into two categories: machine learning (ML) and deep learning (DL), the latter of which is a subset of ML. ML and DL models have been used in several studies to demonstrate their ability to predict and identify cardiac arrhythmias using clinical variables, electrophysiological characteristics, and trends extracted from imaging data. AI has proven to be a valuable aid for cardiologists due to its ability to compute massive amounts of data and detect subtle changes in electric signals and cardiac images, which may potentially increase the risk of recurrent arrhythmias after CA. Despite the fact that these studies involving AI have generated promising outcomes comparable to or superior to human intervention, they have primarily focused on atrial fibrillation while atrial flutter (AFL) and atrial tachycardia (AT) were the subjects of relatively few AI studies. Therefore, the aim of this review is to investigate the interaction of AI algorithms, electrophysiological characteristics, imaging data, risk score calculators, and clinical variables in predicting cardiac arrhythmias following an ablation procedure. This review will also discuss the implementation of these algorithms to enable the detection and prediction of AFL and AT recurrences following CA.
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  • 文章类型: Journal Article
    对低电压区(LVZ)内的激活传播的误解会使房性心动过速(AT)机制分析复杂化,尤其是心房基质重塑患者。这项研究调查了低电压阈值调整(LVTA)对左心房(LA)心动过速激活图解释的影响。
    我们在42例因LA心动过速而接受导管消融术的患者中发现55例房性心动过速,平均LA电压<0.5mV。在LVTA之前和之后,使用LA或两个心房的激活作图来评估AT机制。手术后,患者接受了定期的临床随访。
    比较LVTA前后的激活标测显示了四个类别:(1)9例ATs中AT电路和消融设计的完全变化;(2)16例ATs中AT电路未改变,但需要定制消融设计;(3)3例ATs中旁观者间隙的识别;(4)27例ATs中AT电路和消融设计不变。有效消融,定义为AT终端或电路变化,通过靶向LVTA后激活作图确定的关键区域,在所有9种1型ATs和16种2型ATs中的15种获得。在中位随访16.5个月后,AT的累积自由度为69.3%。
    在LA电压低的患者中,隐藏在LVZ内的传导传播并不少见,但通常被排除在激活映射之外。LVTA可以以可靠的精度揭示这种微妙的传导传播,提高激活映射的准确性,并帮助指导后续消融。
    UNASSIGNED: The misinterpretation of activation propagation within low voltage zone (LVZ) can complicate atrial tachycardia (AT) mechanism analysis, especially in patients with remodeled atrial substrate. This study investigated the impact of low voltage threshold adjustment (LVTA) on left atrial (LA) tachycardia activation mapping interpretation.
    UNASSIGNED: We identified 55 ATs in 42 patients undergoing catheter ablation for LA tachycardia, with a mean LA voltage of < 0.5 mV. Activation mapping of LA or both atria was used to evaluate AT mechanisms before and after LVTA. Patients underwent regular clinic follow-up after the procedure.
    UNASSIGNED: Comparing activation mapping before and after LVTA revealed four categories: (1) complete change in AT circuit and ablation design in 9 ATs; (2) an unchanged AT circuit but tailored ablation design in 16 ATs; (3) identification of bystander gaps in 3 ATs; (4) an unchanged AT circuit and ablation design in 27 ATs. Effective ablation, defined as AT termination or circuit change, was obtained in all 9 Type 1 ATs and 15 of 16 Type 2 ATs by targeting the critical area identified by activation mapping after LVTA. After a median follow-up of 16.5 months, the cumulative freedom from AT was 69.3%.
    UNASSIGNED: In patients with low LA voltage, conduction propagation hidden within LVZ was not uncommon, but is often excluded from activation mapping. LVTA can uncover this subtle conduction propagation with reliable accuracy, improving the veracity of activation mapping, and helping guide subsequent ablation.
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  • 文章类型: Journal Article
    我们对慢通路(SP)和相关的非典型房室(AV)结折返性心动过速(NRT)的变体的理解仍在增长。我们已经确定了沿着三尖瓣环延伸到科赫三角形之外的变体,包括上级,上前和下外侧右心房SP和相关的非典型,快慢AVNRT。我们回顾了每个变体的历史,它们的电生理特征和相关的非典型AVNRT,以及通过导管消融治疗。我们集中力量整理发布的信息,以及一些未发表的,可靠的数据,并显示了电生理观察的陷阱,以及非典型AVNRT诊断的关键。上型的快慢AVNRT模拟了源自房室结附近的腺苷敏感性房性心动过速,可以通过消融周围区域右侧或Valsalva非冠状窦的上SP来成功治疗。使用上前或下外侧右心房SP的快慢AVNRT也模拟了源自三尖瓣环的房性心动过速。我们总结了SP的这些变体之间的相似性,房性心动过速的起源,包括它们的解剖分布和电生理和药理学特征。此外,根据最近的基础研究报告,在成人心脏中存在结节样房室环组织,我们提出术语“房室环心动过速”来指定共享房室环组织作为常见致心律失常底物的心动过速。这篇评论应该帮助读者认识到罕见类型的SP变异和相关的AVNRT,诊断和治愈这些复杂的心动过速。我们希望,有了这个统一的心动过速名称的建议,开启临床电生理学的新篇章.
    Our understanding of the variants of slow pathway (SP) and associated atypical atrioventricular (AV) nodal reentrant tachycardia (NRT) is still growing. We have identified variants extending outside Koch\'s triangle along the tricuspid annulus, including superior, superoanterior and inferolateral right atrial SP and associated atypical, fast-slow AVNRT. We review the history of each variant, their electrophysiological characteristics and related atypical AVNRT, and their treatment by catheter ablation. We focused our efforts on organizing the published information, as well as some unpublished, reliable data, and show the pitfalls of electrophysiological observations, along with keys to the diagnosis of atypical AVNRT. The superior-type of fast-slow AVNRT mimics adenosine-sensitive atrial tachycardia originating near the AV node and can be successfully treated by ablation of a superior SP form the right side of the perihisian region or from the non-coronary sinus of Valsalva. Fast-slow AVNRT using a superoanterior or inferolateral right atrial SP also mimics atrial tachycardia originating from the tricuspid annulus. We summarize the similarities among these variants of SP, and the origin of the atrial tachycardias, including their anatomical distributions and electrophysiological and pharmacological characteristics. Moreover, based on recent basic research reporting the presence of node-like AV ring tissue encircling the annuli in adult hearts, we propose the term \"AV ring tachycardia\" to designate the tachycardias that share the AV ring tissue as a common arrhythmogenic substrate. This review should help the readers recognize rare types of SP variants and associated AVNRT, and diagnose and cure these complex tachycardias. We hope, with this proposal of a unified tachycardia designation, to open a new chapter in clinical electrophysiology.
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