血管母细胞瘤(HBM)是一种以基质细胞和小血管的存在为特征的肿瘤。这些基质细胞代表干细胞,which,由于肿瘤的影响,增殖并分化为创造新血管的“血管形成要素”。血管母细胞瘤的影像学特征类似动静脉畸形(AVM),以明显的血管腮红为特征,存在多个喂食容器,数字减影血管造影(DSA)观察到明显的引流静脉。我们的研究提出了一个例HBM在右小脑半球模仿AVM。两年前,该患者在同一位置被诊断出患有AVM,并接受了血管内栓塞治疗。一个月前,患者经历了严重的头痛,不平衡,恶心,左耳丰满,视力模糊,还有高血压.成像特征提示HBM而非AVM。接下来,患者接受了枕下开颅手术和肿瘤切除术,并插入了外部脑室引流(EVD)。切除肿块的组织病理学报告证实为HBM。总之,AVM和HBM很少同时发生。最近的研究表明,HBM和AVM具有确切的胚胎起源,需要后期的遗传改变才能发展为有症状的病变。需要进一步的研究来澄清这些病变的罕见组合。
Hemangioblastoma (HBM) is a tumor distinguished by the presence of stromal cells and small vessels. These stromal cells represent stem cells, which, due to the influence of the neoplasm, proliferate and differentiate into \"vasoformative elements\" that create new blood vessels. Hemangioblastomas resemble arteriovenous malformation (
AVM) in imaging features, characterized by an apparent vascular blush, the presence of multiple feeding vessels, and evident draining veins observed on digital subtraction angiography (DSA). Our study presents a case of HBM in the right cerebellar hemisphere mimicking
AVM. The patient had been diagnosed with
AVM in the same location two years ago and managed with endovascular embolization. One month prior, the patient experienced severe headaches, imbalance, nausea, left ear fullness, blurry vision, and high blood pressure. The imaging feature suggests HBM rather than
AVM. The patient next underwent sub-occipital craniotomy and tumor resection with external ventricular drainage (EVD) insertion. The histopathological report of the excised mass confirmed HBM. In conclusion,
AVM and HBM rarely occur together. Recent research indicates that HBM and AVM have exact embryologic origins and need later genetic alterations to develop into symptomatic lesions. Further research is required to clarify the uncommon combination of these lesions.