{Reference Type}: Journal Article
{Title}: Influence of casein on the degradation process of polylactide-casein coatings for resorbable alloys.
{Author}: Cesarz-Andraczke K;Staszuk M;Tunçay T;Woźniak A;Smok W;Tunçay B;
{Journal}: Sci Rep
{Volume}: 14
{Issue}: 1
{Year}: 2024 08 15
{Factor}: 4.996
{DOI}: 10.1038/s41598-024-69956-6
{Abstract}: This study used the dip-coating method to develop a new biocompatible coating composed of polylactide (PLA) and casein for ZnMg1.2 wt% alloy implants. It evaluated its impact on the alloy's degradation in a simulated body fluid. After 168 h of immersion in Ringer's solution, surface morphology analysis showed that the PLA-casein coatings demonstrated uniform degradation, with the corrosion current density measured at 48 µA/cm2. Contact angle measurements indicated that the average contact angles for the PLA-casein-coated samples were below 80°, signifying a hydrophilic nature that promotes cell adhesion. Fourier-transform infrared spectroscopy (FTIR) revealed no presence of lactic acid on PLA-casein coatings after immersion, in contrast to pure PLA coatings. Pull-off adhesion tests showed tensile strength values of 7.6 MPa for pure PLA coatings and 5 MPa for PLA-casein coatings. Electrochemical tests further supported the favorable corrosion resistance of the PLA-casein coatings, highlighting their potential to reduce tissue inflammation and improve the biocompatibility of ZnMg1.2 wt% alloy implants.