{Reference Type}: English Abstract {Title}: [Double diabetes mellitus. Double challenge for the exercise prescription. Systematic review]. {Author}: Trujillo LM;von Oetinger A; {Journal}: Rehabilitacion (Madr) {Volume}: 58 {Issue}: 4 {Year}: 2024 Aug 13 暂无{DOI}: 10.1016/j.rh.2024.100866 {Abstract}: Double diabetes (DD) refers to patients with type 1 diabetes who have developed insulin resistance. The objective of this review is to update relevant information on the prescription of physical activity, pharmacological adjustments and consumption of carbohydrates in DD. A systematic search for scientific articles was carried out in the following databases: PubMed, Cochrane, EBSCO, WoS, ScienceDirect and Medline. The evidence analyzed shows that both physical activity (PA) and physical exercise (PE) are essential to achieve metabolic control in people with DD. Physiological considerations such as: insulin adjustments, insulin injection sites, time to perform PA and PE, absolute and relative contraindications are essential to avoid complications, especially hypoglycemia.