{Reference Type}: Journal Article {Title}: Plant-microbiome dynamics through spatial metatranscriptomics and network biology. {Author}: Thingujam D;Liu J;Majeed A;Mukhtar MS; {Journal}: Trends Plant Sci {Volume}: 0 {Issue}: 0 {Year}: 2024 Aug 12 {Factor}: 22.012 {DOI}: 10.1016/j.tplants.2024.07.007 {Abstract}: Climate change threatens global agriculture, impacting plant health and crop yield, while plant microbiomes offer potential solutions to enhance resilience. In this forum, we discuss the prospects of single cell multiome and network science in understanding intricate plant-microbe interactions, providing insights for sustainable agriculture and improved crop productivity for global food security.