{Reference Type}: Journal Article
{Title}: Macroporous polymeric resin for the purification of flavonoids from medicinal plants: A review.
{Author}: Aljawarneh RYA;Che Zain MS;Zakaria F;
{Journal}: J Sep Sci
{Volume}: 47
{Issue}: 15
{Year}: 2024 Aug
{Factor}: 3.614
{DOI}: 10.1002/jssc.202400372
{Abstract}: The purification of flavonoids using the macroporous polymer resin method has gained attention in recent years due to its simplicity, precision, cost-effectiveness, and the ability to separate flavonoids from other constituents. Several studies have been conducted to investigate the efficiency and effectiveness of macroporous polymer resin in purifying flavonoids from various plant sources. This review aims to evaluate the existing literature on macroporous polymer resin purification of flavonoids and provide a comprehensive analysis of the current research trends and advancements in this field. It also highlights the importance of optimizing the adsorption parameters and conditions such as resin type, resin concentration, pH, and temperature for efficient purification of flavonoids using macroporous polymer resin. The key findings of this review reveal that macroporous resins with weak polarity, large surface areas, and pore diameters have a stronger adsorption capacity for flavonoids compared to polar resins. Furthermore, ultrasonic-solvent assisted extraction often combines with macroporous resin for effective the extraction and purification of flavonoids.