{Reference Type}: Journal Article
{Title}: Diabetes mellitus and the risk of spontaneous bacterial peritonitis in patients with liver cirrhosis: a systematic review and meta-analysis.
{Author}: Alhajaji R;Samkari MM;Althobaiti MA;Al-Ahmadi BR;Bugis AM;Bugis AM;Sabbagh FY;Althobaiti SA;Bukari AS;Alqurashi SM;Mshrai HA;Abdelwahab OA;
{Journal}: Ann Saudi Med
{Volume}: 44
{Issue}: 4
{Year}: 2024 Jul-Aug
{Factor}: 1.707
{DOI}: 10.5144/0256-4947.2024.272
{Abstract}: <B>UNASSIGNED: </B>Spontaneous bacterial peritonitis (SBP) represents a critical and potentially lethal condition that typically develops in individuals with liver cirrhosis. This meta-analysis aimed to assess diabetes mellitus (DM) as a risk factor for SBP in liver cirrhotic patients.<BR><B>UNASSIGNED: </B>Following PRISMA guidelines, fifteen studies were included, for a total of 76 815 patients. The risk of bias was assessed using the Newcastle-Ottawa scale (NOS). We represented the results as risk ratios (RR) with the corresponding 95% confidence intervals (CI) using RevMan software. Additionally, we pooled the hazard ratios (HR) for developing SBP in patients with DM from the included studies.<BR><B>UNASSIGNED: </B>The meta-analysis shows a significantly increased risk of SBP in cirrhotic patients with DM (HR: 1.26; 95% CI [1.05-1.51], P=.01; HR: 1.70; 95% CI [1.32-2.18], P<.001).<BR><B>UNASSIGNED: </B>The study signifies that DM is an independent risk factor for SBP, emphasizing the need for targeted preventive measures in this specific population.