{Reference Type}: Journal Article {Title}: Application of Mixed/Augmented Reality in Interventional Cardiology. {Author}: Annabestani M;Olyanasab A;Mosadegh B; {Journal}: J Clin Med {Volume}: 13 {Issue}: 15 {Year}: 2024 Jul 26 {Factor}: 4.964 {DOI}: 10.3390/jcm13154368 {Abstract}: This review explores the transformative applications of augmented reality (AR) and mixed reality (MR) technologies in interventional cardiology. The integration of these cutting-edge systems offers unprecedented potential to enhance visualization, guidance, and outcomes during complex cardiac interventional procedures. This review examines four key domains: (1) medical AR/MR systems and technological foundations; (2) clinical applications across procedures like TAVI, PCI, and electrophysiology mapping; (3) ongoing technology development and validation efforts; and (4) educational and training applications for fostering essential skills. By providing an in-depth analysis of the benefits, challenges, and future directions, this work elucidates the paradigm shift catalyzed by AR and MR in advancing interventional cardiology practices. Through meticulous exploration of technological, clinical, and educational implications, this review underscores the pivotal role of these innovative technologies in optimizing procedural guidance, improving patient outcomes, and driving innovation in cardiovascular care.