{Reference Type}: Journal Article {Title}: Efficiency of Utilizing Bulls with High Immune Response (HIR) in Terms of Reproductive Traits of PHF Cows. {Author}: Sobczyński B;Piwczyński D;Siatka K;Sitkowska B;Kolenda M; {Journal}: Animals (Basel) {Volume}: 14 {Issue}: 15 {Year}: 2024 Jul 23 {Factor}: 3.231 {DOI}: 10.3390/ani14152144 {Abstract}: Reproductive traits in dairy cattle are crucial for herd productivity and profitability. This study investigates the influence of relatedness to high immune response (HIR) Immunity+ sires on reproductive performance indicators in Polish Holstein-Friesian cows. A total of 5094 cows were analyzed, categorized based on their relatedness to HIR Immunity+ sires, and assessed for various reproductive parameters, including age at first insemination, gestation length, days open, calving interval, and calving ease. The results showed that the level of relatedness to HIR Immunity+ sires influenced certain reproductive traits, such as service period, gestation length, and age at first and second calving. Additionally, cows related to HIR Immunity+ sires exhibited a higher frequency of twin pregnancies and more complicated births. While some benefits were observed in certain reproductive traits among cows related to HIR Immunity+ sires, such as reduced age at first insemination and shortened gestation length, the overall impact on reproductive efficiency remains inconclusive. Further studies are needed to fully elucidate the effects of using semen from HIR Immunity+ sires on reproductive performance in dairy cattle.