{Reference Type}: Journal Article
{Title}: Evidence-based review on symptomatic management of Huntington's disease.
{Author}: Shin JH;Yang HJ;Ahn JH;Jo S;Chung SJ;Lee JY;Kim HS;Kim M; ;
{Journal}: J Mov Disord
{Volume}: 0
{Issue}: 0
{Year}: 2024 Aug 9
{Factor}: 4.229
{DOI}: 10.14802/jmd.24140
{Abstract}: Huntington's disease (HD) is a neurodegenerative disorder with a significant impact on patients' quality of life, characterized by motor, behavioral, and cognitive impairments. This evidence-based review, conducted by the Korean Huntington Disease Society (KHDS) task force, systematically examines current pharmacological and non-pharmacological interventions for symptomatic management of HD. Following PRISMA guidelines, databases were searched for studies up to August 2022, focusing on 23 symptoms across four domains: motor, neuropsychological, cognition, and others. This review provides a comprehensive and systematic approach to the management of HD, highlighting the need for more high-quality clinical trials to develop robust evidence-based guidelines.