{Reference Type}: Journal Article
{Title}: 4 vs 7 points self-monitoring blood glucose in gestational diabetes mellitus on diet modification: randomised clinical trial in a single tertiary centre in Malaysia.
{Author}: Berohan ND;Alias H;Ishak S;Mohammed Nawi A;Azman N;Sohaimi D;Kamisan Atan I;Abd Wahab N;Kalok AH;Mohamad AS;Abd Rahman R;
{Journal}: Arch Gynecol Obstet
{Volume}: 0
{Issue}: 0
{Year}: 2024 Aug 7
{Factor}: 2.493
{DOI}: 10.1007/s00404-024-07661-5
{Abstract}: <B>OBJECTIVE: </B>There is no standardized best method on monitoring of patients with gestational diabetes on diet modification in the country. This study aims to investigate the optimum method of self-monitoring blood glucose.<BR><B>METHODS: </B>This is a randomized clinical trial in a single tertiary centre involving patients with gestational diabetes mellitus (GDM) diagnosed based on NICE guideline on diet modification. The patients are randomized in 1:1 ratio to 4 or 7 points self-monitoring blood glucose. The monitoring was required to be done monthly with ultrasound for fetal growth. Blood was taken at recruitment for measurement of serum HbA1c and fructosamine.<BR><B>RESULTS: </B>A total of 200 patients were recruited. There were significantly more Malay patients in the 7 points group (88.9% vs 78.2%, p = 0.033). Multiparous patients were significantly more in the 4 points group (82.2% vs 68.7%, p = 0.033). Both groups were similar in clinical characteristics. There was no statistical difference in the neonatal outcome particularly fetal macrosomia and admission to neonatal intensive care unit.<BR><B>CONCLUSIONS: </B>In patients with GDM on diet modification, self-blood glucose monitoring using either 4 or 7 points resulted in similar maternal and perinatal outcomes. The research was registered under ClinicalTrials.gov (NCT04101396) on 17/9/2019 ( https://register.<BR><B>RESULTS: </B>gov/prs/app/action/SelectProtocol?sid=S00098EN&selectaction=Edit&uid=U0004RD4&ts=2&cx=-qlk1w2 ).