{Reference Type}: Journal Article
{Title}: Chiral bifunctional sulfide-catalyzed enantioselective bromolactonizations of α- and β-substituted 5-hexenoic acids.
{Author}: Sumida S;Okuno K;Mori T;Furuya Y;Shirakawa S;
{Journal}: Beilstein J Org Chem
{Volume}: 20
{Issue}: 0
{Year}: 2024
{Factor}: 2.544
{DOI}: 10.3762/bjoc.20.158
{Abstract}: Enantioselective halolactonizations of sterically less hindered alkenoic acid substrates without substituents on the carbon-carbon double bond have remained a formidable challenge. To address this limitation, we report herein the asymmetric bromolactonization of 5-hexenoic acid derivatives catalyzed by a BINOL-derived chiral bifunctional sulfide.