{Reference Type}: Case Reports
{Title}: Deep brain stimulation for essential tremor in patients with ventriculomegaly.
{Author}: Bouttelgier R;Vandamme S;Ververken F;Maenhoudt W;Du Four S;Van Lerbeirghe J;Vanhauwaert D;Van Damme O;
{Journal}: Surg Neurol Int
{Volume}: 15
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.25259/SNI_979_2023
{Abstract}: <B>UNASSIGNED: </B>Deep brain stimulation of the nucleus ventralis intermedius (VIM-DBS) is considered a safe and effective treatment for medically intractable essential tremor (ET). However, ventriculomegaly can provide a surgical challenge, as there is an increased risk of breaching the ventricle during the procedure, with potential risk of intraventricular hemorrhage and target displacement.<BR><B>UNASSIGNED: </B>In this case series, we report successful bilateral VIM-DBS in a 72-year-old and 69-year-old female ET patient with significant ventriculomegaly. VIM-DBS therapy provided an excellent tremor response. After 5 years, a ventriculoperitoneal shunt was implanted in the first patient due to an incomplete Hakim-Adams triad, with significant improvement in gait and cognition.<BR><B>UNASSIGNED: </B>To the best of our knowledge, we present the first report on VIM-DBS in ET patients with ventriculomegaly and illustrate that VIM-DBS can provide an excellent tremor response in patients with medically intractable ET, even in the context of marked ventriculomegaly.