{Reference Type}: Journal Article
{Title}: Intrasinusoidal bone marrow involvement in mantle cell lymphoma: a case series with review of the main differential diagnoses.
{Author}: Bonometti A;Tzankov A;Alborelli I;Russkamp NF;Dertinger S;Dirnhofer S;
{Journal}: Virchows Arch
{Volume}: 0
{Issue}: 0
{Year}: 2024 Aug 6
{Factor}: 4.535
{DOI}: 10.1007/s00428-024-03885-7
{Abstract}: Intrasinusoidal bone marrow involvement is an infrequent histological pattern observed in a limited number of B and T cell lymphomas. Mantle cell lymphoma is a biologically and prognostically heterogeneous B cell lymphoma that frequently involves the bone marrow, with interstitial, nodular-paratrabecular, or diffuse patterns. Intrasinusoidal bone marrow involvement has been described only anecdotally in this lymphoma. Here, we describe the clinical, histopathological, and molecular features of four patients diagnosed with advanced-stage mantle cell lymphoma, showing intrasinusoidal bone marrow involvement, and other peculiar immunophenotypical features. As similar cases may represent a relevant issue in bone marrow diagnostic histopathology, we also reviewed the literature to discuss differential diagnoses of B and T cell lymphomas with intrasinusoidal bone marrow involvement.