{Reference Type}: Journal Article
{Title}: [A case of IgD-λ multiple myeloma with orbital apex, sieve sinus, and pterygoid sinus occupancy as the first symptom].
{Author}: Li CC;Zhao JH;Liu JF;
{Journal}: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
{Volume}: 59
{Issue}: 7
{Year}: 2024 Jul 7
暂无{DOI}: 10.3760/cma.j.cn115330-20240111-00020
{Abstract}: 本文报道1例以眶尖、筛窦、蝶窦为主要占位病变的IgD-λ型多发性骨髓瘤的病例。患者女，59岁，因“右眼坠胀感1个月余，加重伴视力下降1周”入院。患者鼻窦CT、鼻窦MRI和鼻咽部增强MRI检查均显示右侧眶尖、筛窦、蝶窦占位性病变，肿物呈侵袭性生长，边界不清，轻度骨质破坏。术前诊断为“右侧眶尖肿物”，行内镜经鼻筛窦蝶窦开放术、颅底眶尖肿瘤活检术，术后完善骨髓穿刺及基因检查，明确诊断为IgD-λ型多发性骨髓瘤。该病发病率极低，约占多发性骨髓瘤的1%~2%，耳鼻咽喉科医生遇到鼻窦颅底占位性病变时，须将多发性骨髓瘤纳入鉴别诊断，防止误诊及漏诊。.