{Reference Type}: Journal Article
{Title}: Oncological outcomes of partial thickness calvarial resection for locally advanced scalp malignancies.
{Author}: Farsi S;Odom JQ;Gardner JR;Held M;King D;Sunde J;Vural E;Moreno MA;
{Journal}: Am J Otolaryngol
{Volume}: 45
{Issue}: 6
{Year}: 2024 Aug 2
{Factor}: 2.873
{DOI}: 10.1016/j.amjoto.2024.104456
{Abstract}: <B>OBJECTIVE: </B>Traditionally, locally advanced scalp malignancies have been managed through composite, full-thickness calvarial resection. The aim of this study is to explore the oncologic outcomes of partial calvarial resection for locally invasive scalp malignancies without medullary space invasion, employing a burr-down approach.<BR><B>METHODS: </B>Retrospective case series.<BR><B>METHODS: </B>Tertiary referral center.<BR><B>METHODS: </B>This study analyzed records of 26 adult patients diagnosed with scalp cancer that spread to the calvarial region. Data collected included demographics, medical history, adjuvant therapy details, imaging, surgical outcomes, and postoperative oncological results.<BR><B>RESULTS: </B>26 patients with cancerous scalp lesions necessitating calvarial resection for deep margin control were identified in 22 men and 4 women. Mean age at diagnosis was 72.7 years. The most common histopathological diagnosis was Squamous cell carcinoma (n = 16). Partial removal of the calvarial lesions was achieved in all patients without any intraoperative complications. Twelve patients received adjuvant therapy consisting of the following modalities: radiation (6), chemotherapy (1), immunotherapy (1), a combination of immunotherapy and radiation (2), and a combination of chemotherapy and radiotherapy (2). There was a total of 7 recurrences: local (n = 3,11.5 %), regional (n = 3,11.5 %), distal (n = 1,3.8 %). Long term local control was achieved in (n = 23,88.4 %) of patients. The mean time of follow-up was 19.1 months, and the mean time to recurrence was 15.1 months.<BR><B>CONCLUSIONS: </B>Partial calvarial resection represents a viable, safe, and effective surgical technique for cancerous tissue removal, reducing risks associated with full thickness calvarial resection, and enhancing soft tissue healing when compared to the established gold standard.