{Reference Type}: Journal Article
{Title}: Chemical Constituents Isolated from the Lichen Biome of Selected Species Native to North America.
{Author}: Rakotondraibe HLR;Spjut RW;Addo EM;
{Journal}: Prog Chem Org Nat Prod
{Volume}: 124
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.1007/978-3-031-59567-7_3
{Abstract}: A lichen is a symbiotic association composed of a primary mycobionts and one or more photobionts living mutualistically together, forming a distinct morphological entity beneficial to their partnership and to other associated fungi, photobionts, and bacteria that collectively make up the lichen biome. The taxonomic identification of a lichen species often requires determination of the primary mycobiont's secondary metabolites, the key morphological characteristics of the thallus, and how it relates to other lichen species as seen in DNA phylogeny. This chapter covers lichens and their bionts, taxonomic identification, and their chemical constituents as exemplified by what is found in lichen biomes, especially those endemic to North America. Extraction and isolation, as well as updates on dereplication methods using mass spectrometric GNPS and NMR spectroscopic spin network fingerprint procedures, and marker-based techniques to identify lichens are discussed. The isolation and structure elucidation of secondary metabolites of an endolichenic Penicillium species that produces bioactive compounds will be described in detail.