{Reference Type}: Journal Article {Title}: Biomechanics of step-off drop landings are affected by limb dominance and lead limb in task initiation. {Author}: Kong PW;Tang Y;Lam WK; {Journal}: J Sports Sci {Volume}: 42 {Issue}: 12 {Year}: 2024 Jun 1 {Factor}: 3.943 {DOI}: 10.1080/02640414.2024.2386211 {Abstract}: This study examines the effects of limb dominance and lead limb in task initiation on the kinetics and kinematics of step-off drop landings. Nineteen male participants performed drop landings led by the dominant and non-dominant limbs at 45-cm and 60-cm drop heights. Ground reaction force (GRF) and lower body kinematic data were collected. Between-limb time differences at the initial ground contact were calculated to indicate temporal asymmetry. Statistical Parametric Mapping (SPM) was applied for waveform analysis while two-way repeated measures ANOVA was used for discrete parameters. SPM results revealed greater GRF and lesser ankle dorsiflexion in the lead limb compared to the trail limb in 3 out of 4 landing conditions. The dominant limb displayed a greater forefoot loading rate (45 cm: p=.009, ηp2 = 0.438; 60 cm: p=.035, ηp2 = 0.225) and greater ankle joint quasi-stiffness (45 cm: p < .001, ηp2 = 0.360; 60 cm: p < .001, ηp2 = 0.597) than the non-dominant limb. Not all 380 trials were lead-limb first landings, with a smaller between-limb time difference (p=.009, d = 0.60) at 60 cm (4.1 ± 2.3 ms) than 45 cm (5.6 ± 2.7 ms). In conclusion, the step-off drop landing is not an ideal protocol for examining bilateral asymmetry in lower limb biomechanics due to potential biases introduced by limb dominance and the step-off limb.