{Reference Type}: Letter {Title}: Effectiveness and safety of tenofovir amibufenamide in chronic hepatitis B patients. {Author}: Meng LY;Yang CT;Bao JF;Huang JS; {Journal}: World J Gastroenterol {Volume}: 30 {Issue}: 26 {Year}: 2024 Jul 14 {Factor}: 5.374 {DOI}: 10.3748/wjg.v30.i26.3261 {Abstract}: This letter to the editor relates to the study entitled "Tenofovir amibufenamide vs tenofovir alafenamide for treating chronic hepatitis B: A real-world study", which was recently published by Peng et al. Hepatitis B virus infection represents a significant health burden worldwide and can lead to cirrhosis and even liver cancer. The antiviral drugs currently used to treat patients with chronic hepatitis B infection still have many side effects, so it is crucial to identify safe and effective drugs to inhibit viral replication.