{Reference Type}: Journal Article
{Title}: Superior vena cava isolation using a pentaspline pulsed-field ablation catheter: feasibility and safety in patients undergoing atrial fibrillation catheter ablation.
{Author}: Ollitrault P;Chaumont C;Font J;Manninger M;Conti S;Matusik PT;Mulder BA;Ferchaud V;Pellissier A;Al Khoury M;Milliez P;Champ-Rigot L;Anselme F;
{Journal}: Europace
{Volume}: 26
{Issue}: 7
{Year}: 2024 Jul 2
{Factor}: 5.486
{DOI}: 10.1093/europace/euae160
{Abstract}: <B>OBJECTIVE: </B>Superior vena cava (SVC) isolation during atrial fibrillation catheter ablation is limited by the risk of collateral damage to the sinus node and/or the phrenic nerve. Due to its tissue-specificity, we hypothesized the feasibility and safety of pulsed-field ablation (PFA)-based SVC isolation.<BR><B>RESULTS: </B>One hundred and five consecutive patients undergoing PFA-based AF catheter ablation were prospectively included. After pulmonary vein isolation (±posterior wall isolation and electrical cardioversion), SVC isolation was performed using a standardized workflow. Acute SVC isolation was achieved in 105/105 (100%) patients after 6 ± 1 applications. Transient phrenic nerve stunning occurred in 67/105 (64%) patients but without phrenic nerve palsy at the end of the procedure and at hospital discharge. Transient high-degree sinus node dysfunction occurred in 5/105 (4.7%) patients, with no recurrence at the end of the procedure and until discharge. At the 3-month follow-up visit, no complication occurred.<BR><B>CONCLUSIONS: </B>SVC isolation using a pentaspline PFA catheter is feasible and safe.