{Reference Type}: Journal Article
{Title}: Three montages for Transcranial electric stimulation in predicting the early post-surgery outcome of the facial nerve functioning.
{Author}: Izzo MGA;Rossi Sebastiano D;Catanzaro V;Melillo Y;Togni R;Visani E;Falco J;Casali C;Gemma M;Ferroli P;Gallone A;Cazzato D;Devigili G;Alverà S;Lanteri P;
{Journal}: Clin Neurophysiol
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 19
{Factor}: 4.861
{DOI}: 10.1016/j.clinph.2024.07.008
{Abstract}: <B>OBJECTIVE: </B>We assessed the Transcranial Electrical Stimulation (TES)-induced Corticobulbar-Motor Evoked Potentials (Cb-MEPs) evoked from Orbicularis Oculi (Oc) and Orbicularis Oris (Or) muscles with FCC5h/FCC6h-Mz, C3/C4-Cz and C5/C6/-Cz stimulation, during IntraOperative NeuroMonitoring (IONM) in 30 patients who underwent skull-base surgery.<BR><B>METHODS: </B>before (T0) and after (T1) the surgery, we compared the peak-to-peak amplitudes of Cb-MEPs obtained from TES with C3/C4-Cz, C5/C6-Cz and FCC5h/FCC6h-Mz. Then, we compared the response category (present, absent and peripheral) related to different montages. Finally, we classified the Cb-MEPs data from each patient for concordance with clinical outcome and we assessed the diagnostic measures for Cb-MEPs data obtained from FCC5h/FCC6h-Mz, C3/C4-Cz and C5/C6-Cz TES stimulation.<BR><B>RESULTS: </B>Both at T0 and T1, FCC5h/FCC6h-Mz stimulation evoked larger Cb-MEPs than C3/C4-Cz, less peripheral responses from direct activation of facial nerve than C5/C6-Cz. FCC5h/FCC6h-Mz stimulation showed the best accuracy and specificity of Cb-MEPs for clinical outcomes.<BR><B>CONCLUSIONS: </B>FCC5h/FCC6h-Mz stimulation showed the best performances for monitoring the facial nerve functioning, maintaining excellent diagnostic measures even at low stimulus voltages.<BR><B>CONCLUSIONS: </B>We demonstrated that FCC5h/FCC6h-Mz TES montage for Cb-MEPs in IONM has good accuracy in predicting the post-surgery outcome of facial nerve functioning.