{Reference Type}: Journal Article {Title}: The impact of an anomalous third segment of the vertebral artery on bypass surgery: a case report and literature review. {Author}: Zhao Y;Liu F;Shen F;Liang J;Zhao X; {Journal}: Br J Hosp Med (Lond) {Volume}: 85 {Issue}: 7 {Year}: 2024 Jul 30 {Factor}: 1.286 {DOI}: 10.12968/hmed.2024.0252 {Abstract}: The horizontal part of the third segment (V3) of the vertebral artery (VA) is a critical anastomotic site for bypass procedures involving either donor or recipient vessels. It is rare for the V3 segment to deviate from its typical course of passing through the atlanto-transverse foramen. V3 anomaly encountered in occipital artery (OA)-V3 bypass surgery has not been previously reported. Here, we present a case involving a patient undergoing bypass surgery due to recurrent post-stent occlusion at the first segment (V1) of the left VA. During the operation, it was noted that the V3 horizontal segment could not be identified within the left VA groove, leading to initial suspicion of left V3 disuse atrophy attributed to prolonged chronic ischaemia. Consequently, there was a need to modify the operative method and to transition from an OA-V3 bypass to an OA-posterior inferior cerebellar artery bypass. Post-operative computed tomography angiography confirmed that indeed, the left V3 did not traverse through the transverse foramen of the atlas and instead entered the dural membrane between the first cervical vertebra (C1) and the second cervical vertebra (C2).