{Reference Type}: Journal Article
{Title}: EVolution in ALS diagnosis: molecular markers in extracellular vesicles.
{Author}: Codron P;Millecamps S;Corcia P;
{Journal}: Trends Mol Med
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 27
{Factor}: 15.272
{DOI}: 10.1016/j.molmed.2024.07.006
{Abstract}: The identification of biomarkers for amyotrophic lateral sclerosis (ALS) is a central issue in disease research. In a recent article, Chatterjee et al. show that blood extracellular vesicles (EVs) with high levels of transactive response DNA-binding protein 43 (TDP-43) accurately discriminate patients with ALS from controls and correlate with disease severity, providing a promising biomarker for early diagnosis and monitoring.