{Reference Type}: Journal Article
{Title}: Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids.
{Author}: Noel A;Zhang J;Shen H;Saxena A;Groeltz-Thrush J;Li G;Rahe MC;
{Journal}: Viruses
{Volume}: 16
{Issue}: 7
{Year}: 2024 Jun 25
{Factor}: 5.818
{DOI}: 10.3390/v16071023
{Abstract}: A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia. Hypothesis-free metagenomics identified a previously unreported picornavirus (USA/IA26017/2023), and further phylogenetic analysis classified USA/IA26017/2023 as an aphthovirus related to bovine rhinitis B virus. Viral nucleic acid was localized to lesions of bronchitis using in situ hybridization. This marks the first report of a picornavirus putatively causing respiratory disease in goats and highlights the potential for cross-species transmission of aphthoviruses.