{Reference Type}: Letter
{Title}: Letter to the editor regarding "Induction chemotherapy regimes in first-line treatment for locoregionally advanced nasopharyngeal carcinoma: A network meta-analysis and cost-effectiveness analysis.
{Author}: Ganesh PS;Pathoor NN;Gopal RK;
{Journal}: Oral Oncol
{Volume}: 157
{Issue}: 0
{Year}: 2024 Oct 23
{Factor}: 5.972
{DOI}: 10.1016/j.oraloncology.2024.106954
{Abstract}: The research paper offers a detailed analysis of induction chemotherapy regimens for locoregionally advanced nasopharyngeal carcinoma (LA-NPC), assessing their effectiveness and cost-effectiveness. It presents important data on disease-free survival and overall survival outcomes. However, this letter suggests several improvements. It advocates for the inclusion of patient-centered outcomes such as quality of life and functional status to better gauge treatment impacts on daily living. Additionally, it calls for a more thorough investigation into long-term adverse effects and the role of biomarkers in tailoring treatments. It also recommends a comparative analysis of cost-effectiveness across various healthcare systems and the creation of practical guidelines for regimen selection. These proposed changes aim to enhance the study's practical relevance and clinical applicability.