{Reference Type}: Journal Article
{Title}: STX-bpc: "Brightening" the path to neuronal inhibition.
{Author}: Wan J;Li Y;
{Journal}: Cell Chem Biol
{Volume}: 31
{Issue}: 7
{Year}: 2024 Jul 18
{Factor}: 9.039
{DOI}: 10.1016/j.chembiol.2024.06.008
{Abstract}: In this issue of Cell Chemical Biology, Elleman et al.1 introduce a transformative chemical approach to control neuronal activity with high spatial and temporal resolution. The authors present STX-bpc, a potent neurotoxin that naturally inhibits voltage-gated sodium channels (NaVs), complementing available optogenetic methods for manipulating neuronal activity, cellular communication, and behavior.