{Reference Type}: Journal Article
{Title}: Glottic insufficiency caused by vocal fold atrophy with or without sulcus: systematic review of outcome measurements.
{Author}: van den Broek EMJM;Mes SD;Heijnen BJ;Langeveld APM;van Benthem PPG;Sjögren EV;
{Journal}: Eur Arch Otorhinolaryngol
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 18
{Factor}: 3.236
{DOI}: 10.1007/s00405-024-08751-5
{Abstract}: <B>OBJECTIVE: </B>Identifying outcome measurements instruments (OMIs) to evaluate treatment efficacy in patients with vocal fold atrophy and/or sulcus.<BR><B>METHODS: </B>Systematic review of records published before March 2021 by searching Pubmed and EMBASE. Included studies reported on adults (> 18 year) with dysphonia caused by glottic insufficiency due to vocal fold atrophy with or without sulcus, who were enrolled into a randomized controlled trial, a non-randomized controlled trial, a case-controlled study or a cohort study. All included studies described an intervention with at least one outcome measurement.<BR><B>RESULTS: </B>A total of 5456 studies were identified. After removing duplicates, screening title and abstract and full text screening of selected records, 34 publications were included in final analysis. From these 50 separate OMIs were recorded and categorized according to the ELS protocol by DeJonckere et al. (Eur Arch Otorhinolaryngol 258: 77-82, 2001). With most OMIs being used in multiple studies the total number of OMIs reported was 265. Nineteen (19) individual OMIs accounted for 80% of reports. The most frequently used OMIs according to category were: VHI and VHI-10 (subjective evaluation); G of GRBAS (perceptual evaluation); F0, Jitter and Shimmer (acoustic evaluation); MPT and MFR (aerodynamic evaluation) and glottic closure and mucosal wave (endoscopic evaluation). Of these OMIs VHI had a high percentage of significance of 90%.<BR><B>CONCLUSIONS: </B>This systematic review identifies the most used OMIs in patients with glottic incompetency due to vocal fold atrophy and/or sulcus as a step toward defining a Core Outcome Set (COS) for this population.<BR><B>UNASSIGNED: </B>238274.