{Reference Type}: Journal Article {Title}: A review of the key ingredients in industrial formulations of baby wet wipes. {Author}: Petrović T;Poljarević J;Nikolić S;Stojković-Filipović J;Mihajlović-Lalić LE; {Journal}: Int J Dermatol {Volume}: 0 {Issue}: 0 {Year}: 2024 Jul 17 {Factor}: 3.204 {DOI}: 10.1111/ijd.17351 {Abstract}: The skin of newborns is classified as sensitive, with a higher risk of skin barrier disruption and irritation of a diapered area. Despite dermatologist recommendations to use only water and a cloth for cleaning, most of the population still relies on the comforts of modern parenting, which includes intensive daily usage of baby wet wipes. Novel baby formulations are designed following the concept of infant skin health, containing a gentle cleanser, suitable emollient, and buffer system enabling a slightly acidic pH value and they are free of ethyl alcohol. Thus, it is important to understand the chemical background of such a complex liquid formulation, with emphasis on its safety. In line with this, the present paper discusses the scientific background of various chemical compounds found in baby wipe formulations to improve the understanding of wet wipe designs and direct them toward more skin-friendly solutions.