{Reference Type}: Journal Article {Title}: Influences of bisphenol A on hydrogen production from food waste by thermophilic dark fermentation. {Author}: Yang YJ;Zhu MJ; {Journal}: Environ Res {Volume}: 260 {Issue}: 0 {Year}: 2024 Nov 1 {Factor}: 8.431 {DOI}: 10.1016/j.envres.2024.119625 {Abstract}: The extensive use of plastic products in food packaging and daily life makes them inevitably enter the treatment process of food waste (FW). Plasticizer as a new pollutant is threatening the dark fermentation of FW. Our study showed that bisphenol A (BPA) at > 250 mg/L had a significant inhibition on hydrogen production from FW by thermophilic dark fermentation. The endogenous ATP content and lactate dehydrogenase (LDH) release showed that high level of BPA not only inhibited the growth of hydrogen-producing consortium, but also led to cell death. In addition, BPA mainly affects the hydrogen-producing consortium by reducing cell membrane fluidity, damaging cell membrane integrity and reducing cell membrane potential, resulting in cell death. This study provides some new insights into the mechanism of the effect of BPA on hydrogen production from FW by thermophilic dark fermentation, and lays the foundation on the utilization of FW.